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CONTINUOUS INTRAVENOUS INJECTION OF TYPHOID VACCINE IN TREATMENT OF CERTAIN OPHTHALMIC DISEASES

CONTINUOUS INTRAVENOUS INJECTION OF TYPHOID VACCINE IN TREATMENT OF CERTAIN OPHTHALMIC DISEASES Abstract FOR MANY years artificial fever, induced in the hypertherm cabinet or by single injections of foreign protein or typhoid vaccine, has been used in the treatment of various diseases of the eye. In the past decade attention has been directed particularly toward the use of single, rapid intravenous injections of typhoid vaccine. A drawback of this type of therapy is the unpredictable febrile reaction. In some cases extremely severe chills and high fever occur, whereas in others several injections are required, over a period of days, before the proper degree of fever is secured. Moreover, typhoid therapy is frequently withheld from elderly patients or persons with heart disease because of the risk entailed in a severe reaction. Solomon and Somkin1 in 1942 introduced the method of controlled hyperpyrexia by the continous intravenous administration of typhoid vaccine. It occurred to us that this type of therapy might well be applied References 1. Solomon, H. A., and Somkin, E.: An Improved Method of Obtaining Sustained Controlled Hyperpyrexia with Triple Typhoid Vaccine , Am. J. M. Sc. 203:736, 1942.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

CONTINUOUS INTRAVENOUS INJECTION OF TYPHOID VACCINE IN TREATMENT OF CERTAIN OPHTHALMIC DISEASES

Archives of Ophthalmology , Volume 42 (2) – Aug 1, 1949

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References (1)

Publisher
American Medical Association
Copyright
Copyright © 1949 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1949.00900050128002
Publisher site
See Article on Publisher Site

Abstract

Abstract FOR MANY years artificial fever, induced in the hypertherm cabinet or by single injections of foreign protein or typhoid vaccine, has been used in the treatment of various diseases of the eye. In the past decade attention has been directed particularly toward the use of single, rapid intravenous injections of typhoid vaccine. A drawback of this type of therapy is the unpredictable febrile reaction. In some cases extremely severe chills and high fever occur, whereas in others several injections are required, over a period of days, before the proper degree of fever is secured. Moreover, typhoid therapy is frequently withheld from elderly patients or persons with heart disease because of the risk entailed in a severe reaction. Solomon and Somkin1 in 1942 introduced the method of controlled hyperpyrexia by the continous intravenous administration of typhoid vaccine. It occurred to us that this type of therapy might well be applied References 1. Solomon, H. A., and Somkin, E.: An Improved Method of Obtaining Sustained Controlled Hyperpyrexia with Triple Typhoid Vaccine , Am. J. M. Sc. 203:736, 1942.Crossref

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Aug 1, 1949

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