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BACTERIOPHAGE THERAPY OF STAPHYLOCOCCIC SEPTIC OBSTRUCTION OF THE CAVERNOUS SINUS: II. REPORT OF CASES

BACTERIOPHAGE THERAPY OF STAPHYLOCOCCIC SEPTIC OBSTRUCTION OF THE CAVERNOUS SINUS: II. REPORT OF... Abstract In the present paper we purpose to consider the 45 patients whose records have been accessioned to our bacteriophage files who presented evidence of an impending or well established septic obstruction of the cavernous sinus : first, the 14 patients who survived ; second, the 23 patients who died within five days after the initiation of bacteriophage therapy, and, third, the 8 patients who succumbed after an interval varying from eight days to five months. We do not include as a survivor any patient known to have succumbed to a sequel to this disease, even though he was discharged from the hospital "improved" or "cured." Such patients have been classed among those who died. We include in this report, however, a few patients who because of lack of positive blood cultures were not accepted for our staphylococcemia series. The case numbers in parentheses refer to that series.1 A patient whose case References 1. MacNeal, W. J.; Frisbee, F. C., and McRae, M. A.: Staphylococcemia 1931 to 1940: Five Hundred Patients , Am. J. Clin. Path. 12:281-294 ( (June) ) 1942. 2. MacNeal, W. J., and Frisbee, F. C.: Bacteriophage as a Therapeutic Agent in Staphylococcus Bacteremia , J. A. M. A. 99:1150-1155 ( (Oct. 1) ) 1932.Crossref 3. MacNeal, W. J.: Recent Developments in Bacteriophage Therapy , New York State J. Med. 41:1531-1536 ( (Aug. 1) ) 1941. 4. Smith, C. H.: An Observation on the Treatment of Osteomyelitis of the Skull, with Report of a Case , Laryngoscope 45:703-711 ( (Sept.) ) 1935. 5. MacNeal, W. J.; Frisbee, F. C., and McRae, M. A.: Bacteriophage Service in Staphylococcal Infections , Am. J. Clin. Path. 11:549-561 ( (July) ) 1941. 6. Eagleton, W. P. : Cavernous Sinus Thrombophlebitis , New York, The Macmillan Company, 1926. 7. Hyde, W. H.: Pericoronal Infection Leading to Cavernous Sinus Thrombosis , Am. J. Orthodontics 24:393-394 ( (April) ) 1938.Crossref 8. Mainzer, F. S.: Cavernous Sinus Thrombosis , Pennsylvania M. J. 34: 38-43 ( (Oct.) ) 1930. 9. J. A. M. A. 117:111 [ (July 12) ] 1941Crossref 10. Dr. Wells P. Eagleton and Dr. William H. Hahn furnished the records of this patient. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

BACTERIOPHAGE THERAPY OF STAPHYLOCOCCIC SEPTIC OBSTRUCTION OF THE CAVERNOUS SINUS: II. REPORT OF CASES

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References (8)

Publisher
American Medical Association
Copyright
Copyright © 1943 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1943.00880150015001
Publisher site
See Article on Publisher Site

Abstract

Abstract In the present paper we purpose to consider the 45 patients whose records have been accessioned to our bacteriophage files who presented evidence of an impending or well established septic obstruction of the cavernous sinus : first, the 14 patients who survived ; second, the 23 patients who died within five days after the initiation of bacteriophage therapy, and, third, the 8 patients who succumbed after an interval varying from eight days to five months. We do not include as a survivor any patient known to have succumbed to a sequel to this disease, even though he was discharged from the hospital "improved" or "cured." Such patients have been classed among those who died. We include in this report, however, a few patients who because of lack of positive blood cultures were not accepted for our staphylococcemia series. The case numbers in parentheses refer to that series.1 A patient whose case References 1. MacNeal, W. J.; Frisbee, F. C., and McRae, M. A.: Staphylococcemia 1931 to 1940: Five Hundred Patients , Am. J. Clin. Path. 12:281-294 ( (June) ) 1942. 2. MacNeal, W. J., and Frisbee, F. C.: Bacteriophage as a Therapeutic Agent in Staphylococcus Bacteremia , J. A. M. A. 99:1150-1155 ( (Oct. 1) ) 1932.Crossref 3. MacNeal, W. J.: Recent Developments in Bacteriophage Therapy , New York State J. Med. 41:1531-1536 ( (Aug. 1) ) 1941. 4. Smith, C. H.: An Observation on the Treatment of Osteomyelitis of the Skull, with Report of a Case , Laryngoscope 45:703-711 ( (Sept.) ) 1935. 5. MacNeal, W. J.; Frisbee, F. C., and McRae, M. A.: Bacteriophage Service in Staphylococcal Infections , Am. J. Clin. Path. 11:549-561 ( (July) ) 1941. 6. Eagleton, W. P. : Cavernous Sinus Thrombophlebitis , New York, The Macmillan Company, 1926. 7. Hyde, W. H.: Pericoronal Infection Leading to Cavernous Sinus Thrombosis , Am. J. Orthodontics 24:393-394 ( (April) ) 1938.Crossref 8. Mainzer, F. S.: Cavernous Sinus Thrombosis , Pennsylvania M. J. 34: 38-43 ( (Oct.) ) 1930. 9. J. A. M. A. 117:111 [ (July 12) ] 1941Crossref 10. Dr. Wells P. Eagleton and Dr. William H. Hahn furnished the records of this patient.

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Mar 1, 1943

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