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Retinal Vein Occlusion and Traditional Risk Factors for Atherosclerosis

Retinal Vein Occlusion and Traditional Risk Factors for Atherosclerosis EPIDEMIOLOGY Retinal Vein Occlusion and Traditional Risk Factors for Atherosclerosis Paul R. A. O’Mahoney; David T. Wong, MD, FRCSC; Joel G. Ray, MD, MSc, FRCPC Objective: To determine whether retinal vein occlu- the association was less pronounced for diabetes mellitus sion (RVO) is related to systemic hypertension, diabe- (OR, 1.5; 95% CI, 1.1-2.0). Similar results were found in tes mellitus, and hyperlipidemia. cases with central RVO and branch RVO. The percentage of cases with any form of RVO attributed to hypertension Methods: We systematically retrieved all studies pub- was 47.9% (95% CI, 31.2%-63.1%), to diabetes mellitus was lished between January 1985 and July 2007 that com- 4.9% (95% CI, 0.8%-11.5%), and to hyperlipidemia was pared cases with any form of RVO, including central and 20.1% (95% CI, 5.9%-43.8%). branch RVO, with controls. We generated pooled odds ratios (ORs) and estimates of the population- Conclusions: Hypertension and hyperlipidemia are com- attributable risk percentages for systemic hypertension, mon risk factors for RVO in adults, and diabetes melli- diabetes mellitus, and hyperlipidemia. tus is less so. It remains to be determined whether low- ering blood pressure and/or serum lipid levels can improve Results: Of 21 studies, including 2916 cases and 28 646 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Ophthalmology American Medical Association

Retinal Vein Occlusion and Traditional Risk Factors for Atherosclerosis

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References (39)

Publisher
American Medical Association
Copyright
Copyright 2008 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6165
eISSN
2168-6173
DOI
10.1001/archopht.126.5.692
pmid
18474782
Publisher site
See Article on Publisher Site

Abstract

EPIDEMIOLOGY Retinal Vein Occlusion and Traditional Risk Factors for Atherosclerosis Paul R. A. O’Mahoney; David T. Wong, MD, FRCSC; Joel G. Ray, MD, MSc, FRCPC Objective: To determine whether retinal vein occlu- the association was less pronounced for diabetes mellitus sion (RVO) is related to systemic hypertension, diabe- (OR, 1.5; 95% CI, 1.1-2.0). Similar results were found in tes mellitus, and hyperlipidemia. cases with central RVO and branch RVO. The percentage of cases with any form of RVO attributed to hypertension Methods: We systematically retrieved all studies pub- was 47.9% (95% CI, 31.2%-63.1%), to diabetes mellitus was lished between January 1985 and July 2007 that com- 4.9% (95% CI, 0.8%-11.5%), and to hyperlipidemia was pared cases with any form of RVO, including central and 20.1% (95% CI, 5.9%-43.8%). branch RVO, with controls. We generated pooled odds ratios (ORs) and estimates of the population- Conclusions: Hypertension and hyperlipidemia are com- attributable risk percentages for systemic hypertension, mon risk factors for RVO in adults, and diabetes melli- diabetes mellitus, and hyperlipidemia. tus is less so. It remains to be determined whether low- ering blood pressure and/or serum lipid levels can improve Results: Of 21 studies, including 2916 cases and 28 646

Journal

JAMA Ophthalmology – American Medical Association

Published: May 1, 2008

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