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LIPIDS AND PROTEINS OF PLASMA IN PATIENTS WITH DISEASES OF THE NERVOUS SYSTEM

LIPIDS AND PROTEINS OF PLASMA IN PATIENTS WITH DISEASES OF THE NERVOUS SYSTEM Abstract THE BIOCHEMICAL defects in neurological and psychotic disorders are poorly understood. A recent review1 indicates that investigators do not agree on the changes in the lipid constituents of blood plasma associated with epilepsy and the psychoses. Information concerning the effect of nervous diseases on plasma proteins is limited. The data presented in this paper are concerned with analyses of plasma lipids and proteins in patients with a variety of disorders of the nervous system. METHODS AND MATERIAL Twenty-six male medical students and staff members served as controls. The patients were divided into three groups: (a) neurological patients with and without complications; (b) psychotic patients with and without complications, and (c) subjects with a variety of medical and surgical disorders. The neurological diseases with complications included infections and inflammatory reactions (12 patients), neoplasms of the brain (2 patients), circulatory disturbances (11 patients), degenerative or demyelinating diseases (7 patients), metabolic or References 1. Peters, J. P., and Van Slyke, D. D.: Quantitative Clinical Chemistry Interpretations , Ed. 2, Baltimore, Williams & Wilkins Company, 1946. 2. Longsworth, L. G.: Observations of Electrophoretic Boundaries , Ann. New York Acad. Sc. 39:187-202, 1939.Crossref 3. Sperry, W. M., and Brand, F. C.: Colorimetric Determination of Cholesterol , J. Biol. Chem. 150:315-324, 1943. 4. Allen, R. J. L.: Estimation of Phosphorus , Biochem. J. 34:858-865, 1940. 5. Schmidt, G.; Bennotti, J.; Hershman, B., and Thannhauser, S. J.: A Micromethod for Quantitative Partition of Phospholipide Mixtures into Monoaminophosphatides and Sphingomyelin , J. Biol. Chem. 166:505-511, 1946. 6. Thannhauser, S. J.: Medical Progress: Serum Lipids and Their Value in Diagnosis , New England J. Med. 237:515-522, 546-552, 1947.Crossref 7. Keys, A.; Brozek, J.; Henschel, A.; Mickelsen, O., and Taylor, H. L.: The Biology of Human Starvation , Minneapolis, University of Minnesota Press, 1950. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Neurology & Psychiatry American Medical Association

LIPIDS AND PROTEINS OF PLASMA IN PATIENTS WITH DISEASES OF THE NERVOUS SYSTEM

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References (8)

Publisher
American Medical Association
Copyright
Copyright © 1952 American Medical Association. All Rights Reserved.
ISSN
0096-6886
DOI
10.1001/archneurpsyc.1952.02320150065006
Publisher site
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Abstract

Abstract THE BIOCHEMICAL defects in neurological and psychotic disorders are poorly understood. A recent review1 indicates that investigators do not agree on the changes in the lipid constituents of blood plasma associated with epilepsy and the psychoses. Information concerning the effect of nervous diseases on plasma proteins is limited. The data presented in this paper are concerned with analyses of plasma lipids and proteins in patients with a variety of disorders of the nervous system. METHODS AND MATERIAL Twenty-six male medical students and staff members served as controls. The patients were divided into three groups: (a) neurological patients with and without complications; (b) psychotic patients with and without complications, and (c) subjects with a variety of medical and surgical disorders. The neurological diseases with complications included infections and inflammatory reactions (12 patients), neoplasms of the brain (2 patients), circulatory disturbances (11 patients), degenerative or demyelinating diseases (7 patients), metabolic or References 1. Peters, J. P., and Van Slyke, D. D.: Quantitative Clinical Chemistry Interpretations , Ed. 2, Baltimore, Williams & Wilkins Company, 1946. 2. Longsworth, L. G.: Observations of Electrophoretic Boundaries , Ann. New York Acad. Sc. 39:187-202, 1939.Crossref 3. Sperry, W. M., and Brand, F. C.: Colorimetric Determination of Cholesterol , J. Biol. Chem. 150:315-324, 1943. 4. Allen, R. J. L.: Estimation of Phosphorus , Biochem. J. 34:858-865, 1940. 5. Schmidt, G.; Bennotti, J.; Hershman, B., and Thannhauser, S. J.: A Micromethod for Quantitative Partition of Phospholipide Mixtures into Monoaminophosphatides and Sphingomyelin , J. Biol. Chem. 166:505-511, 1946. 6. Thannhauser, S. J.: Medical Progress: Serum Lipids and Their Value in Diagnosis , New England J. Med. 237:515-522, 546-552, 1947.Crossref 7. Keys, A.; Brozek, J.; Henschel, A.; Mickelsen, O., and Taylor, H. L.: The Biology of Human Starvation , Minneapolis, University of Minnesota Press, 1950.

Journal

A.M.A. Archives of Neurology & Psychiatry – American Medical Association

Published: Mar 1, 1952

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