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T. Putnam (1937)
EVIDENCES OF VASCULAR OCCLUSION IN MULTIPLE SCLEROSIS AND ENCEPHALOMYELITISJournal of Nervous and Mental Disease, 37
F. Wohlwill (1928)
Ueber Encephalomyelitis bei MasernZtschr. f. d. ges. Neurol. u. Psychiat., 112
T. Putnam (1935)
STUDIES IN MULTIPLE SCLEROSIS: IV. ENCEPHALITIS AND SCLEROTIC PLAQUES PRODUCED BY VENULAR OBSTRUCTIONJournal of Nervous and Mental Disease, 33
R. Pfeifer, S. Parker (1932)
GRUNDLEGENDE UNTERSUCHUNGEN FÜR DIE ANGIO-ARCHITEKTONIK DES MENSCHLICHEN GEHIRNSJournal of Nervous and Mental Disease, 75
G. Ward (1929)
ENCEPHALOMYELITIS FOLLOWING VACCINATION.The Lancet, 214
W. Spielmeyer (1928)
Local VulnerabilityZtschr. f. d. ges. Neurol. u. Psychiat., 118
Franz Lucksch (1932)
Ueber Enzephalitis nach Varicellae, Variola, nach Vaccination und nach MorbilliMed. Klin., 28
F. Wohlwill (1928)
Über Encephalomyelitis bei MasernZeitschrift für die gesamte Neurologie und Psychiatrie, 112
Abstract The characteristic pathologic changes uniformly present in the acute stage of vaccinal encephalitis, first seen by Turnbull1 and described by Lucksch,2 encephalitis associated with variola (fig. 1 A), as described by Lucksch, and encephalitis following measles (fig. 1 B), as first described by Wohlwill,3 include a pathologic reaction not recognized before the last decade. This focal change is the perivascular, extra-adventitial and progressive glial reaction and demyelinization which occur along the course of veins for variable distances. In the present study small and large veins were involved but the medium and large vessels presented a marked glial reaction. Study of serial sections stained by the Nissl method showed that the small branches of a vein have no or a minimal glial reaction. As one follows the branch through to vessels of larger caliber the microglial collar about the vein becomes progressively more marked and more widespread. As References 1. Turnbull, H. M., and McIntosh, J.: Encephalomyelitis Following Vaccination , Brit. J. Exper. Path. 7:181, 1926. 2. Lucksch, Franz: Ueber Enzephalitis nach Varicellae, Variola, nach Vaccination und nach Morbilli , Med. Klin. 28:1554 ( (Nov. 4) ) 1932. 3. Wohlwill, F.: Ueber Encephalomyelitis bei Masern , Ztschr. f. d. ges. Neurol. u. Psychiat. 112:20, 1928.Crossref 4. Spielmeyer, W.: Local Vulnerability , Ztschr. f. d. ges. Neurol. u. Psychiat. 118:1 ( (Dec.) ) 1928Crossref 5. abstr., Arch. Neurol. & Psychiat. 23:161 ( (Jan.) ) 1930. 6. Putnam, Tracy J.: Studies in Multiple Sclerosis: IV. "Encephalitis" and Sclerotic Plaques Produced by Venular Obstruction , Arch. Neurol. & Psychiat. 33:929 ( (May) ) 1935. 7. Pfeifer, R. A.: Grundlegende Untersuchungen für die Angioarchitektonik des menschlichen Gehirns , Berlin, Julius Springer, 1930. 8. Personal observation on material in the Brain Anatomical Institute, University of Leipzig. 9. Adamkiewicz, Albert: Die Blutgefässe des menschlichen Rückenmarkes , Sitzungsb. d. k. Akad. d. Wissensch., Math.-naturw. Cl. 84:469, 1882. 10. Kadyi, H.: Ueber die Blutgefässe des menschlichen Rückenmarkes , Lemberg, Gubynowicz & Schmidt, 1889. 11. Personal communication to the author. 12. Putnam, Tracy J.: Evidences of Vascular Occlusion in Multiple Sclerosis and "Encephalomyelitis," Arch. Neurol. & Psychiat. , to be published.
Archives of Neurology & Psychiatry – American Medical Association
Published: Mar 1, 1937
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