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Optimizing the Hachinski Ischemic Scale

Optimizing the Hachinski Ischemic Scale SPECIAL ARTICLE Vladimir Hachinski, MD, FRCPC, DSc; Shahram Oveisgharan, MD; A. Kimball Romney, PhD; William R. Shankle, MS, MD Background: Vascular causes and factors remain the Results: Two optimized HIS versions were identified that most significant preventable component of cognitive dis- classify patients with vascular dementia vs those with non- orders of elderly individuals. The Hachinski Ischemic vascular dementia as well as or more accurately than the Score (HIS) is the questionnaire most commonly used original HIS instrument. Assuming the HIS instrument mea- for diagnosis of vascular dementia. sures only a single dimension, correspondence analysis iden- tified the 7 most discriminative HIS items. Binary scoring Objective: To consolidate and further validate the HIS. (0, 1) of these items led to a 7-item HIS model that classi- fied as well as the original 13-item HIS instrument. By merg- Design: The Canadian Study for Health and Aging was ing highly similar HIS items and applying correspon- used for this study. It was a cohort study conducted in 3 dence analysis, a 5-item composite HIS model was created waves in 1991, 1996-1997, and 2001-2002. The HIS con- that measures 2 meaningful dimensions of information and taining 13 items was subjected to correspondence http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Neurology American Medical Association

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References (17)

Publisher
American Medical Association
Copyright
Copyright 2012 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6149
eISSN
2168-6157
DOI
10.1001/archneurol.2011.1698
pmid
21987392
Publisher site
See Article on Publisher Site

Abstract

SPECIAL ARTICLE Vladimir Hachinski, MD, FRCPC, DSc; Shahram Oveisgharan, MD; A. Kimball Romney, PhD; William R. Shankle, MS, MD Background: Vascular causes and factors remain the Results: Two optimized HIS versions were identified that most significant preventable component of cognitive dis- classify patients with vascular dementia vs those with non- orders of elderly individuals. The Hachinski Ischemic vascular dementia as well as or more accurately than the Score (HIS) is the questionnaire most commonly used original HIS instrument. Assuming the HIS instrument mea- for diagnosis of vascular dementia. sures only a single dimension, correspondence analysis iden- tified the 7 most discriminative HIS items. Binary scoring Objective: To consolidate and further validate the HIS. (0, 1) of these items led to a 7-item HIS model that classi- fied as well as the original 13-item HIS instrument. By merg- Design: The Canadian Study for Health and Aging was ing highly similar HIS items and applying correspon- used for this study. It was a cohort study conducted in 3 dence analysis, a 5-item composite HIS model was created waves in 1991, 1996-1997, and 2001-2002. The HIS con- that measures 2 meaningful dimensions of information and taining 13 items was subjected to correspondence

Journal

JAMA NeurologyAmerican Medical Association

Published: Feb 1, 2012

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