Disease Course of Charcot-Marie-Tooth Disease Type 2 and Comorbidity—Reply
Abstract
In reply We thank Gemignani and Marbini for their important comments on our 5-year prospective study of disease course in CMT2. First, it is unlikely that comorbidity played an important role in the neurological deterioration of our patients; comorbidity causing polyneuropathy was scarce in our cohort. Two patients had previously been treated for hypothyroid disease. During follow-up, 2 other patients developed type 2 diabetes mellitus. Second, as the authors mention, sensory complaints and...