Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Trauma and Multiple Sclerosis

Trauma and Multiple Sclerosis those associated with recent MS exac- vate MS, nor is it now universally ac- ences, New Jersey Medical School, Uni- erbations would be expected to resolve cepted that BBB abnormalities are the versity of Medicine and Dentistry of in this time. Only one large prospec- first changes seen in an active MS le- New Jersey, 185 S Orange Ave, Room tive study of this type has been carried sion. In fact, recent evidence from MRI H506, Newark, NJ 07013-2714. out to date, but unfortunately, MRI spectroscopy and MRI diffusion stud- scans were not routinely performed. ies indicates that abnormalities can oc- REFERENCES In this study, Sibley et al observed 170 cur in normal-appearing white matter patients with MS for up to 8 years. No before gadolinium enhancement is de- 1. Goodin DS, Ebers GC, Johnson KP, Rodriguez MD, significant correlation was found be- tected, suggesting that brain inflam- Sibley WA, Wolinsky JS. The relationship of MS to physical trauma and psychological stress: re- tween mechanical trauma and MS ex- mation may cause a secondary change port of the Therapeutics and Technology Assess- acerbations or progression. However, in the BBB rather than the opposite. ment Subcommittee of the American Academy http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Neurology American Medical Association

Trauma and Multiple Sclerosis

Hachinski, Vladimir
JAMA Neurology , Volume 57 (7) – Jul 1, 2000
Download PDF
1 page

Trauma and Multiple Sclerosis

Abstract

those associated with recent MS exac- vate MS, nor is it now universally ac- ences, New Jersey Medical School, Uni- erbations would be expected to resolve cepted that BBB abnormalities are the versity of Medicine and Dentistry of in this time. Only one large prospec- first changes seen in an active MS le- New Jersey, 185 S Orange Ave, Room tive study of this type has been carried sion. In fact, recent evidence from MRI H506, Newark, NJ 07013-2714. out to date, but unfortunately, MRI...
Loading next page...
 
/lp/american-medical-association/trauma-and-multiple-sclerosis-K0YXe13uKe

References (7)

Publisher
American Medical Association
Copyright
Copyright 2000 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6149
eISSN
2168-6157
DOI
10.1001/archneur.57.7.1078
Publisher site
See Article on Publisher Site

Abstract

those associated with recent MS exac- vate MS, nor is it now universally ac- ences, New Jersey Medical School, Uni- erbations would be expected to resolve cepted that BBB abnormalities are the versity of Medicine and Dentistry of in this time. Only one large prospec- first changes seen in an active MS le- New Jersey, 185 S Orange Ave, Room tive study of this type has been carried sion. In fact, recent evidence from MRI H506, Newark, NJ 07013-2714. out to date, but unfortunately, MRI spectroscopy and MRI diffusion stud- scans were not routinely performed. ies indicates that abnormalities can oc- REFERENCES In this study, Sibley et al observed 170 cur in normal-appearing white matter patients with MS for up to 8 years. No before gadolinium enhancement is de- 1. Goodin DS, Ebers GC, Johnson KP, Rodriguez MD, significant correlation was found be- tected, suggesting that brain inflam- Sibley WA, Wolinsky JS. The relationship of MS to physical trauma and psychological stress: re- tween mechanical trauma and MS ex- mation may cause a secondary change port of the Therapeutics and Technology Assess- acerbations or progression. However, in the BBB rather than the opposite. ment Subcommittee of the American Academy

Journal

JAMA Neurology – American Medical Association

Published: Jul 1, 2000

There are no references for this article.