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Achievements of the Last Century in Neurosurgery and a View to the 21st Century

Achievements of the Last Century in Neurosurgery and a View to the 21st Century dures, and endoscopy was matched by the introduction for the last disease was the molecular pathogenesis well by neurologists of high-tech treatments for neuromuscu- understood. During the Decade of the Brain (1991- lar diseases, cancer, stroke, and immune-mediated dis- 2000), there were great advances in molecular genetics eases of the nervous system. Prion proteins were found and understanding the pathogenesis of neurologic dis- to be responsible for Creutzfeldt-Jakob disease, kuru, eases, preparing the way for novel treatments, including and other neurologic conditions, leading to the award of gene therapy, in the new millennium. Nobel Prizes for Carleton Gajdusek, MD, in 1976 and Stanley Prusiner, MD, in 1997. By century’s end, there were advances in understanding the pathogenesis of the Corresponding author: Thomas R. Swift, MD, Department notorious “big five” neurological diseases: multiple scle- of Neurology, Medical College of Georgia, 1459 Laney rosis, Parkinson disease, Alzheimer disease, amyotro- Walker Blvd, Augusta, GA 30912 (e-mail: tswift phic lateral sclerosis, and muscular dystrophy, but only @neuro.mcg.edu). SPECIAL MILLENNIUM ARTICLE Achievements of the Last Century in Neurosurgery and a View to the 21st Century James I. Ausman, MD, PhD he beginning of the 20th century was marked by biology. The use of computers http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Neurology American Medical Association

Achievements of the Last Century in Neurosurgery and a View to the 21st Century

Ausman, James I.
JAMA Neurology , Volume 57 (1) – Jan 1, 2000
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Publisher
American Medical Association
Copyright
Copyright 2000 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6149
eISSN
2168-6157
DOI
10.1001/archneur.57.1.61
Publisher site
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Abstract

dures, and endoscopy was matched by the introduction for the last disease was the molecular pathogenesis well by neurologists of high-tech treatments for neuromuscu- understood. During the Decade of the Brain (1991- lar diseases, cancer, stroke, and immune-mediated dis- 2000), there were great advances in molecular genetics eases of the nervous system. Prion proteins were found and understanding the pathogenesis of neurologic dis- to be responsible for Creutzfeldt-Jakob disease, kuru, eases, preparing the way for novel treatments, including and other neurologic conditions, leading to the award of gene therapy, in the new millennium. Nobel Prizes for Carleton Gajdusek, MD, in 1976 and Stanley Prusiner, MD, in 1997. By century’s end, there were advances in understanding the pathogenesis of the Corresponding author: Thomas R. Swift, MD, Department notorious “big five” neurological diseases: multiple scle- of Neurology, Medical College of Georgia, 1459 Laney rosis, Parkinson disease, Alzheimer disease, amyotro- Walker Blvd, Augusta, GA 30912 (e-mail: tswift phic lateral sclerosis, and muscular dystrophy, but only @neuro.mcg.edu). SPECIAL MILLENNIUM ARTICLE Achievements of the Last Century in Neurosurgery and a View to the 21st Century James I. Ausman, MD, PhD he beginning of the 20th century was marked by biology. The use of computers

Journal

JAMA Neurology – American Medical Association

Published: Jan 1, 2000

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