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Lupus Anticoagulant and Stroke-Reply

Lupus Anticoagulant and Stroke-Reply Abstract In Reply. —We thank Drs Levine and Welch for their interest, for their letter, and for sharing with us a preprint of their article1 on the subject of the lupuslike anticoagulant or lupus inhibitor and its presumptive association with cerebral infarcts. Our recent publication2 agrees with the concluding paragraph of their letter: the lupuslike anticoagulant appears to be associated with an increased risk for stroke, and other factors (perhaps even those as yet unknown) may contribute to this risk. Since it is theoretically impossible to ever know all of the potential risk factors for stroke, their last point—that it is unclear if the presence of the lupuslike anticoagulant alone, in the absence of other risk factors, can increase the probability of cerebral infarction—seems obvious. Our case report presented a young (31-year-old) man with a stroke who had a lupuslike anticoagulant in the absence of other known risk factors for infarction; References 1. Levine SR, Welch KMA: Cerebrovascular ischemia associated with lupus anticoagulant . Stroke 1987;18:257-263.Crossref 2. Tabachnik-Schor NF, Lipton SA: Association of lupuslike anticoagulant and nonvasculitic cerebral infarction . Arch Neurol 1986;43:851-852.Crossref 3. Tan EM, Cohen AS, Fries JF: The 1982 revised criteria for the classification of systemic lupus erythematosus . Arthritis Rheum 1982;25:1271-1277.Crossref 4. Dosekun A, Pollack VE, Glas-Greenwalt P, et al: Ancrod in systemic lupus erythematosus with thrombosis: Clinical and fibrinolysis effects . Arch Intern Med 1984;144:37-42.Crossref 5. Bonita R, Scragg R, Stewart A, et al: Cigarette smoking and risk of premature stroke in men and women . Br Med J 1986;293:6-8.Crossref 6. Hart RG, Miller VT, Coull BM, et al: Cerebral infarction associated with lupus anticoagulants: Preliminary report . Stroke 1984;15:114-118.Crossref 7. Fisher M, McGehee W: Cerebral infarct, TIA, and lupus inhibitor . Neurology 1986;36:1234-1237.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Neurology American Medical Association

Lupus Anticoagulant and Stroke-Reply

Lipton, Stuart A.; Schor, Nina F.
Archives of Neurology , Volume 44 (7) – Jul 1, 1987
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References (7)

Publisher
American Medical Association
Copyright
Copyright © 1987 American Medical Association. All Rights Reserved.
ISSN
0003-9942
eISSN
1538-3687
DOI
10.1001/archneur.1987.00520190007005
Publisher site
See Article on Publisher Site

Abstract

Abstract In Reply. —We thank Drs Levine and Welch for their interest, for their letter, and for sharing with us a preprint of their article1 on the subject of the lupuslike anticoagulant or lupus inhibitor and its presumptive association with cerebral infarcts. Our recent publication2 agrees with the concluding paragraph of their letter: the lupuslike anticoagulant appears to be associated with an increased risk for stroke, and other factors (perhaps even those as yet unknown) may contribute to this risk. Since it is theoretically impossible to ever know all of the potential risk factors for stroke, their last point—that it is unclear if the presence of the lupuslike anticoagulant alone, in the absence of other risk factors, can increase the probability of cerebral infarction—seems obvious. Our case report presented a young (31-year-old) man with a stroke who had a lupuslike anticoagulant in the absence of other known risk factors for infarction; References 1. Levine SR, Welch KMA: Cerebrovascular ischemia associated with lupus anticoagulant . Stroke 1987;18:257-263.Crossref 2. Tabachnik-Schor NF, Lipton SA: Association of lupuslike anticoagulant and nonvasculitic cerebral infarction . Arch Neurol 1986;43:851-852.Crossref 3. Tan EM, Cohen AS, Fries JF: The 1982 revised criteria for the classification of systemic lupus erythematosus . Arthritis Rheum 1982;25:1271-1277.Crossref 4. Dosekun A, Pollack VE, Glas-Greenwalt P, et al: Ancrod in systemic lupus erythematosus with thrombosis: Clinical and fibrinolysis effects . Arch Intern Med 1984;144:37-42.Crossref 5. Bonita R, Scragg R, Stewart A, et al: Cigarette smoking and risk of premature stroke in men and women . Br Med J 1986;293:6-8.Crossref 6. Hart RG, Miller VT, Coull BM, et al: Cerebral infarction associated with lupus anticoagulants: Preliminary report . Stroke 1984;15:114-118.Crossref 7. Fisher M, McGehee W: Cerebral infarct, TIA, and lupus inhibitor . Neurology 1986;36:1234-1237.Crossref

Journal

Archives of Neurology – American Medical Association

Published: Jul 1, 1987

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