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Ischemic Cerebrovascular Complications of Pregnancy

Ischemic Cerebrovascular Complications of Pregnancy Abstract • Pregnancy increases the risk of focal ischemic cerebrovascular events, apparently to about 13 times the expected rate outside of pregnancy in the case of cerebral infarction. The distribution of the underlying pathophysiologic mechanisms causing the cerebrovascular symptoms in pregnant patients differs considerably from the distribution in the general population. Although most focal ischemic lesions that occur during pregnancy seem to be the result of arterial occlusion, cerebral venous thrombosis is still a prominent factor in causing such lesions. Arterial occlusions tend to occur during the second and third trimesters of pregnancy and during the first week after delivery, whereas the venous occlusions tend to occur one to four weeks after childbirth. When possible, treatment of patients with focal ischemic neurologic symptoms is based on a precise definition of the underlying pathophysiologic mechanism and its appropriate treatment. When this is not possible, patients are treated according to categorization based on the temporal profile of the focal deficit. References 1. Jennett WB, Cross JN: Influence of pregnancy and oral contraception on the incidence of strokes in women of childbearing age . Lancet 1967;1:1019-1023.Crossref 2. Schoenberg BS, Whisnant JP, Taylor WF, et al: Strokes in women of childbearing age: A population study . Neurology 1970;20:181-189.Crossref 3. Huggenberg HR, Kesselring F.: Postpartuale cerebrale komplikationen . Gynaecologia 1958; 146:312-315. 4. Lorincz AB, Moore RY: Puerperal cerebral venous thrombosis . Am J Obstet Gynecol 1962;83:311-318. 5. Goldman JA, Eckerling B, Gans B: Intracranial venous sinus thrombosis in pregnancy and puerperium: Report of 15 cases . 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Ischemic Cerebrovascular Complications of Pregnancy

Archives of Neurology , Volume 42 (11) – Nov 1, 1985

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References (198)

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American Medical Association
Copyright
Copyright © 1985 American Medical Association. All Rights Reserved.
ISSN
0003-9942
eISSN
1538-3687
DOI
10.1001/archneur.1985.04060100092030
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Abstract

Abstract • Pregnancy increases the risk of focal ischemic cerebrovascular events, apparently to about 13 times the expected rate outside of pregnancy in the case of cerebral infarction. The distribution of the underlying pathophysiologic mechanisms causing the cerebrovascular symptoms in pregnant patients differs considerably from the distribution in the general population. Although most focal ischemic lesions that occur during pregnancy seem to be the result of arterial occlusion, cerebral venous thrombosis is still a prominent factor in causing such lesions. Arterial occlusions tend to occur during the second and third trimesters of pregnancy and during the first week after delivery, whereas the venous occlusions tend to occur one to four weeks after childbirth. When possible, treatment of patients with focal ischemic neurologic symptoms is based on a precise definition of the underlying pathophysiologic mechanism and its appropriate treatment. 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Journal

Archives of NeurologyAmerican Medical Association

Published: Nov 1, 1985

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