Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Acute Dysautonomia and Polyneuropathy

Acute Dysautonomia and Polyneuropathy Abstract • A patient experienced an acute dysautonomia manifested by an inability to eat without vomiting, severe constipation, dry mouth, and orthostatic hypotension. One month later, a severe polyneuropathy supervened. The patient subsequently experienced an atonic bladder. Biopsy specimens obtained from the bowel wall disclosed an inflammatory infiltrate within the autonomic nerves consisting of lymphocytes and plasma cells. To our knowledge, this is the first time that inflammatory infiltrates have been demonstrated within the autonomic nerves in a patient with an acute dysautonomia, suggesting a relationship between this illness and the inflammatory polyneuropathies. The patient subsequently had a severe polyneuropathy, lending support to this conclusion. References 1. Young RR, Asbury AK, Adams RD, et al: Pure dysautonomia with recovery . Trans Am Neurol Assoc 1969;94:355-357. 2. Hopkins A, Neville B, Bannister A: Autonomic neuropathy of acute onset . Lancet 1974;1:769-771.Crossref 3. Low PA, Dych PJ, Lambert EH, et al: Acute panautonomic neuropathy . Ann Neurol 1983; 13:412-417.Crossref 4. Lichtenfeld P: Autonomic dysautonomia in the Guillain-Barré syndrome . Am J Med 1971;56:772-780.Crossref 5. Appenzeller O, Kornfeld M: Acute pandysautonomia . Arch Neurol 1973;29:334-339.Crossref 6. Colan RV, Snead OC, Oh JJ, et al: Acute autonomic and sensory neuropathy . Ann Neurol 1980;8:441-444.Crossref 7. Feit H, Glasberg M, Ireton C, et al: Peripheral neuropathy and starvation after gastric partitioning for morbid obesity . Ann Intern Med 1982;96:453-455.Crossref 8. Eisen A, Humphrey P: The Guillain-Barré syndrome . Arch Neurol 1974;30:438-443.Crossref 9. Asbury AK, Arnason BG, Adams RD: The inflammatory lesion in idiopathic polyneuritis: Its role in pathogenesis . Medicine 1969;48:173-215.Crossref 10. Matsuyami H, Haymaker W: Distribution of lesions in the Landry-Guillain-Barré syndrome, with emphasis on involvement of the sympathetic system . Acta Neuropathol 1967; 8:230.Crossref 11. Dyck PJ: Chronic inflammatory polyradiculoneuropathy . Mayo Clin Proc 1975;50:621-637. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Neurology American Medical Association

Acute Dysautonomia and Polyneuropathy

Archives of Neurology , Volume 41 (10) – Oct 1, 1984

Loading next page...
 
/lp/american-medical-association/acute-dysautonomia-and-polyneuropathy-zUwWk5Bi23

References (13)

Publisher
American Medical Association
Copyright
Copyright © 1984 American Medical Association. All Rights Reserved.
ISSN
0003-9942
eISSN
1538-3687
DOI
10.1001/archneur.1984.04050210102025
Publisher site
See Article on Publisher Site

Abstract

Abstract • A patient experienced an acute dysautonomia manifested by an inability to eat without vomiting, severe constipation, dry mouth, and orthostatic hypotension. One month later, a severe polyneuropathy supervened. The patient subsequently experienced an atonic bladder. Biopsy specimens obtained from the bowel wall disclosed an inflammatory infiltrate within the autonomic nerves consisting of lymphocytes and plasma cells. To our knowledge, this is the first time that inflammatory infiltrates have been demonstrated within the autonomic nerves in a patient with an acute dysautonomia, suggesting a relationship between this illness and the inflammatory polyneuropathies. The patient subsequently had a severe polyneuropathy, lending support to this conclusion. References 1. Young RR, Asbury AK, Adams RD, et al: Pure dysautonomia with recovery . Trans Am Neurol Assoc 1969;94:355-357. 2. Hopkins A, Neville B, Bannister A: Autonomic neuropathy of acute onset . Lancet 1974;1:769-771.Crossref 3. Low PA, Dych PJ, Lambert EH, et al: Acute panautonomic neuropathy . Ann Neurol 1983; 13:412-417.Crossref 4. Lichtenfeld P: Autonomic dysautonomia in the Guillain-Barré syndrome . Am J Med 1971;56:772-780.Crossref 5. Appenzeller O, Kornfeld M: Acute pandysautonomia . Arch Neurol 1973;29:334-339.Crossref 6. Colan RV, Snead OC, Oh JJ, et al: Acute autonomic and sensory neuropathy . Ann Neurol 1980;8:441-444.Crossref 7. Feit H, Glasberg M, Ireton C, et al: Peripheral neuropathy and starvation after gastric partitioning for morbid obesity . Ann Intern Med 1982;96:453-455.Crossref 8. Eisen A, Humphrey P: The Guillain-Barré syndrome . Arch Neurol 1974;30:438-443.Crossref 9. Asbury AK, Arnason BG, Adams RD: The inflammatory lesion in idiopathic polyneuritis: Its role in pathogenesis . Medicine 1969;48:173-215.Crossref 10. Matsuyami H, Haymaker W: Distribution of lesions in the Landry-Guillain-Barré syndrome, with emphasis on involvement of the sympathetic system . Acta Neuropathol 1967; 8:230.Crossref 11. Dyck PJ: Chronic inflammatory polyradiculoneuropathy . Mayo Clin Proc 1975;50:621-637.

Journal

Archives of NeurologyAmerican Medical Association

Published: Oct 1, 1984

There are no references for this article.