Effect of Baclofen on Seizure Frequency
Abstract
Abstract To the Editor —The conclusion of Terrence et al1 that baclofen in usual therapeutic doses does not seem to be epileptogenic may be based on chance observations. The epilepsy of their six controlled patients usually had a good spontaneous prognosis and was not suitable for pharmacologic treatment. One of these six patients showed a major change in seizure frequency concurrent with baclofen administration, yet previous monthly variation of seizure frequency was not described,...