Clomiphene as an Anticonvulsant Drug: A Case Report
Abstract
Abstract The effect of sex steroids on seizure disorders is controversial. Two controlled trials showed no effect1,2; however, there are other descriptions of patients whose attacks were aggravated by oral contraceptives.3,4 Some experimental evidence suggests that estrogens increase the electrical excitability of the brain.5 Clomiphene citrate, an antiestrogen drug, has been used to treat oligospermia and asthenospermia.6-8 In contrast to its use in women for infertility, where the drug is...