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R. Caplan, G. Dobben (1969)
Endocrine studies in patients with the "empty sella syndrome".Archives of internal medicine, 123 6
D. Charles, D. Snell (1979)
Cerebrospinal fluid rhinorrheaThe Laryngoscope, 89
R. Mortara, H. Norrell (1970)
Consequences of a deficient sellar diaphragm.Journal of neurosurgery, 32 5
T. Sutton, J. Vézina (1974)
Co-existing pituitary adenoma and intrasellar arachnoid invagination.The American journal of roentgenology, radium therapy, and nuclear medicine, 122 3
C. Fager (1973)
Nature and treatment of cerebrospinal fluid rhinorrhea in pituitary tumors.The Surgical clinics of North America, 53 2
E. Macgee, J. Cauthen, C. Brackett (1970)
Meningitis following acute traumatic cerebrospinal fluid fistula.Journal of neurosurgery, 33 3
A. Ommaya (1964)
Cerebrospinal fluid rhinorrheaNeurology, 14
A. Nutkiewicz, D. Defeo, R. Kohut, S. Fierstein (1980)
Cerebrospinal fluid rhinorrhea as a presentation of pituitary adenoma.Neurosurgery, 6 2
A. Ommaya (1976)
Spinal fluid fistulae.Clinical neurosurgery, 23
Abstract Cerebrospinal fluid rhinorrhea is a rare complication of untreated pituitary adenoma. The case presented exemplifies many of the features typical of this condition, including the potential for late-developing bacterial meningitis. REPORT OF A CASE A 24-year-old man had a five-day history of productive cough, sore throat, and general malaise. On the day of admission to the hospital, he experienced a severe generalized headache, nausea, vomiting, and photophobia. There was a ten-year history of intermittent issue of clear fluid from the nose, attributed to chronic sinusitis.The patient was alert, fully oriented, and in obvious pain from headache. Clear fluid dripped from both nostrils. He was afebrile. There was mild pain with full neck flexion. The examination results were otherwise unremarkable.Lumbar puncture showed clear CSF under a pressure of 170 mm H2O and the following values: glucose, 106 mg/dL; protein, 59 mg/dL; and WBCs, 7/cu mm (82% segmented References 1. Charles D, Snell D: Cerebrospinal fluid rhinorrhea . Laryngoscope 1979;89:822-826.Crossref 2. Ommaya A: Cerebrospinal fluid rhinorrhea . Neurology 1964;14:106-113.Crossref 3. Fager C: Nature and treatment of cerebrospinal fluid rhinorrhea in pituitary tumors . Surg Clin North Am 1973;53:283-290. 4. Nutkiewicz A, DeFeo DR, Kohut RI, et al: Cerebrospinal fluid rhinorrhea as a presentation of pituitary adenoma . Neurosurgery 1980;6:195-197.Crossref 5. Sutton T, Vezina J: Co-existing pituitary adenoma and intrasellar arachnoid invagination . AJR 1974;122:508-510.Crossref 6. Caplan R, Dobben G: Endocrine studies in patients with the 'empty sella syndrome.' Arch Intern Med 1969;123:611-619.Crossref 7. Mortara R, Norrell H: Consequences of a deficient sellar diaphragm . J Neurosurg 1970;32:565-573.Crossref 8. Ommaya A: Spinal fluid fistulae . Clin Neurosurg 1976;23:363-392. 9. MacGee E, Cauthen J, Brackett C: Meningitis following acute traumatic cerebrospinal fluid fistula . J Neurosurg 1970;33:312-316.Crossref
Archives of Neurology – American Medical Association
Published: Jul 1, 1982
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