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Periodic Alternating Nystagmus

Periodic Alternating Nystagmus This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract To the Editor.—Recently, Keane described periodic alternating nystagmus (PAN) associated with down-beating nystagmus in a 54-year-old woman with demyelinating disease, who had undergone autopsy (Arch Neurol 30:399, 1974). It was suggested that the pertinent lesion lay in the vestibular nuclei along the floor of the fourth ventricle, although other sites of demyelination involved the periaqueductal gray matter, both medial longitudinal fasciculi, both restiform bodies, and the spinal cord. The following case of PAN in an 11-yearold girl was associated with unilateral seeding by astrocytoma cells in the vestibular nuclei at the pontomedullary level. Report of a Case.—An 11-year-old girl had a left frontal astrocytoma partially resected, followed by radiation therapy and administration of vincristin. Eleven months later she was cachectic and had a spastic quadriparesis. The left pupil was 1 mm larger than the right, and both were briskly reactive. Nystagmus was present with the following characteristics. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Neurology American Medical Association

Periodic Alternating Nystagmus

Archives of Neurology , Volume 32 (6) – Jun 1, 1975

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Publisher
American Medical Association
Copyright
Copyright © 1975 American Medical Association. All Rights Reserved.
ISSN
0003-9942
eISSN
1538-3687
DOI
10.1001/archneur.1975.00490480088015
Publisher site
See Article on Publisher Site

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract To the Editor.—Recently, Keane described periodic alternating nystagmus (PAN) associated with down-beating nystagmus in a 54-year-old woman with demyelinating disease, who had undergone autopsy (Arch Neurol 30:399, 1974). It was suggested that the pertinent lesion lay in the vestibular nuclei along the floor of the fourth ventricle, although other sites of demyelination involved the periaqueductal gray matter, both medial longitudinal fasciculi, both restiform bodies, and the spinal cord. The following case of PAN in an 11-yearold girl was associated with unilateral seeding by astrocytoma cells in the vestibular nuclei at the pontomedullary level. Report of a Case.—An 11-year-old girl had a left frontal astrocytoma partially resected, followed by radiation therapy and administration of vincristin. Eleven months later she was cachectic and had a spastic quadriparesis. The left pupil was 1 mm larger than the right, and both were briskly reactive. Nystagmus was present with the following characteristics.

Journal

Archives of NeurologyAmerican Medical Association

Published: Jun 1, 1975

There are no references for this article.