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M. Yahr, R. Duvoisin, M. Schear, R. Barrett, M. Hoehn (1969)
Treatment of parkinsonism with levodopa.Archives of neurology, 21 4
Ralph Druckmax, D. Seelinger, B. Thulin (1962)
CHRONIC INVOLUNTARY MOVEMENTS INDUCED BY PHENOTHIAZINESThe Journal of Nervous and Mental Disease, 135
R. Stolze, G. Ule (1957)
[Significance of trigeminal degeneration in speech disorders in hereditary ataxia].Der Nervenarzt, 28 1
Nickey WM Dill RE (1968)
Dyskinesias in rats following chemical stimulation of the neostriatumTexas Rep Biol Med, 26
G. Crane (1968)
Tardive dyskinesia in patients treated with major neuroleptics: a review of the literature.The American journal of psychiatry, 124 8
D. Greenblatt, J. Dominick, B. Stotsky, A. Dimascio (1968)
PHENOTHIAZINE‐INDUCED DYSKINESIA IN NURSING‐HOME PATIENTS *Journal of the American Geriatrics Society, 16
H. Sutcher, R. Underwood, R. Beatty, O. Sugar (1971)
Orofacial dyskinesia. A dental dimension.JAMA, 216 9
J. Simpson (1971)
PSYCHOTROPIC DRUGS AND DYSFUNCTIONS OF THE BASAL GANGLIAJournal of Neurology, Neurosurgery & Psychiatry, 34
J. Demars (1966)
NEUROMUSCULAR EFFECTS OF LONG‐TERM PHENOTHIAZINE MEDICATION, ELECTROCONVULSIVE THERAPY AND LEUCOTOMYThe Journal of Nervous and Mental Disease, 143
B. Hughes (1965)
Involuntary movements following stereotactic operations for Parkinsonism with special reference to hemi-chorea (ballismus)Journal of Neurology, Neurosurgery & Psychiatry, 28
B. Nashold, D. Slaughter (1969)
Effects of stimulating or destroying the deep cerebellar regions in man.Journal of neurosurgery, 31 2
E. Christensen, J. Moller, A. Faurbye (1970)
NEUROPATHOLOGICAL INVESTIGATION OF 28 BRAINS FROM PATIENTS WITH DYSKINESIAActa Psychiatrica Scandinavica, 46
K. Heinrich, I. Wegener, H. Bender (1968)
Späte extrapyramidale Hyperkinesen bei neuroleptischer LangzeittherapiePharmacopsychiatrie, 1
Paulson Gw (1968)
An evaluation of the permanence of the "tardive dyskinesias".Diseases of the nervous system, 29
A. Faurbye, P. Rasch, P. Petersen, G. Brandborg, H. Pakkenberg (1964)
NEUROLOGICAL SYMPTOMS IN PHARMAGOTHERAPY OF PSYCHOSESActa Psychiatrica Scandinavica, 40
A. Greenhouse (1966)
On Chorea, Lupus Erythematosus, and Cerebral ArteritisJAMA Internal Medicine, 117
Richard Hunter, C. Earl, S. Thornicroft (1964)
AN APPARENTLY IRREVERSIBLE SYNDROME OF ABNORMAL MOVEMENTS FOLLOWING PHENOTHIAZINE MEDICATION.Proceedings of the Royal Society of Medicine, 57
Carpenter MB (1966)
Brain stem nuclei in studies of experimental dyskinesiaJ Neurosurg, 24
Stern F (1922)
Die Epidemische Encephalitis
J. Sigwald, D. Bouttier, C. Raymondeaud, C. Piot (1959)
[4 Cases of facio-bucco-linguo-masticatory dyskinesis of prolonged development following treatment with neuroleptics].Revue neurologique, 100
W. Schmidt, L. Jarcho (1966)
Persistent dyskinesias following phenothiazine therapy. Report of five cases and a review of the literature.Archives of neurology, 14 4
M. Ke (1962)
Tetanus-like reactions to the phenothiazine drugs; "the grimacing syndrome".The New Zealand Medical Journal, 61
Greenhouse AH (1966)
On chorea, lupus erythematous, and cerebral arteritisArch Intern Med, 117
O. Appenzeller, J. Biehl (1968)
Mouthing in the elderly: a cerebellar sign.Journal of the neurological sciences, 6 2
L. Hurwitz, D. Montgomery (1965)
Persistent choreo-athetotic movements in liver disease.Archives of neurology, 13 4
H. Siede, H. Müller (1967)
CHOREIFORM MOVEMENTS AS SIDE EFFECTS OF PHENOTHIAZINE MEDICATION IN GERIATRIC PATIENTSJournal of the American Geriatrics Society, 15
Thiebaut F (1968)
Diseases of the Basal Ganglia
G. Crane (1970)
High doses of trifluperazine and tardive dyskinesia.Archives of neurology, 22 2
Van Bogaert L (1934)
Syndrome extrapyramidal au cours d'une maladie de PickJ Belg Neurol Psychiat, 34
Bouttier D Sigwald J (1959)
Quatre cas de dyskinésie facio-bucco-linguo-masticatrice á èvolution prolongée secondaire á un traitment par les neuroleptiquesRev Neurol, 100
Deniker P Delay J (1967)
Syndrome choreique idiopathique rappelant la sémiologie d' imprégnation chronique par les neuroleptiquesAnn Medicopsych, 125
Schonecker M (1957)
Ein eigentumliches Syndrom im ovalen Bereich bei Megaphen ApplikationNervenarzt, 28
Levy G Marie P (1920)
Le Syndrome Excito-Moteur de L'Encephalite EpidemiqueRev Neurol, 36
Abstract Oral-facial dyskinesia is not uncommonly encountered as side-effect of chronic phenothiazine treatment or levodopa therapy, is less commonly seen during the course of known hereditary or acquired basal ganglia diseases, and is rarely seen under other circumstances. Two cases of spontaneous oral-facial dyskinesia are described. The pathology and pathophysiology of this type of involuntary movement disorder are unknown, and the prognosis is uncertain. No effective treatment is yet available. References 1. Schonecker M: Ein eigentumliches Syndrom im ovalen Bereich bei Megaphen Applikation . Nervenarzt 28:35-42, 1957. 2. Sigwald J, Bouttier D, Raymondeaud C, et al: Quatre cas de dyskinésie facio-bucco-linguo-masticatrice á èvolution prolongée secondaire á un traitment par les neuroleptiques . Rev Neurol 100:751-755, 1959. 3. Druckman R, Seelinger D, Thulin B: Chronic involuntary movements induced by phenothiazines . J Nerv Ment Dis 135:69-76, 1962.Crossref 4. Faurbye A, Rasch PJ, Petersen PB, et al: Neurological symptoms in pharmacotherapy of psychoses . Acta Psychiat Scand 40:10-27, 1964.Crossref 5. Hunter R, Earl CJ, Thornicroft S: An apparently irreversible syndrome of abnormal movements following phenothiazine medication . Proc Roy Soc Med 57:758-762, 1964. 6. Schmidt WR, Jarcho LW: Persistent dyskinesias following phenothiazine therapy: Report of five cases and a review of the literature . Arch Neurol 14:369-377, 1966.Crossref 7. Siede H, Müller HF: Choreiform movements as side effects of phenothiazine medication in geriatric patients . J Amer Geriat Soc 15:517-522, 1967. 8. Crane GE: Tardive dyskinesia in patients treated with major neuroleptics: A review of the literature . Amer J Psychiat 124( (suppl) ):40-48, 1968. 9. Heinrich K, Wegener I, Bender HJ: Spate Extrapyramidale hyperkinesen bei Neuroleptischer Langzeittherapie . Pharmakopsychiat Neuropsychopharm 1:169-195, 1968.Crossref 10. Crane GE: High Doses of trifluperazine and tardive dyskinesia . Arch Neurol 22:176-180, 1970.Crossref 11. Yahr MD, Duvoisin RC, Schear MJ, et al: Treatment of parkinsonism with levodopa . Arch Neurol 21:343-354, 1969.Crossref 12. Bruyn GW: Huntington's chorea , in Vinken PJ, Bruyn GW (eds): Diseases of the Basal Ganglia . New York, Elsevier Publishing Co, 1968. 13. Thiebaut F: Sydenham's chorea , Vinken PJ, Bruyn GW (eds): Diseases of the Basal Ganglia . New York, Elsevier Publishing Co, 1968. 14. Degwitz R: Extrapyramidal motor disorders following long-term treatment with neuroleptic drugs , in Psychotropic Drugs and Dysfunctions of the Basal Ganglia , bulletin 1938, Public Health Service, 1969. 15. Marie P, Levy G: Le Syndrome Excito-Moteur de L'Encephalite Epidemique . Rev Neurol 36:513-536, 1920. 16. Stern F: Die Epidemische Encephalitis . Berlin, Springer Verlag, 1922. 17. Sutcher HD, Underwood RB, Beatty RA, et al: Orofacial dyskinesia a dental dimension . JAMA 216:1459-1463, 1971.Crossref 18. Appenzeller O, Biehl JP: Mouthing in the elderly: A cerebellar sign . J Neurol Sci 6:249-260, 1968.Crossref 19. Greenhouse AH: On chorea, lupus erythematous, and cerebral arteritis . Arch Intern Med 117:389-393, 1966.Crossref 20. Hurwitz LJ, Montgomery DAO: Persistent choreo-athetotic movements in liver disease . Arch Neurol 13:421-426, 1965.Crossref 21. Van Bogaert L: Syndrome extrapyramidal au cours d'une maladie de Pick . J Belg Neurol Psychiat 34:315-320, 1934. 22. Greenblatt L, Dominick JR, Stotsky BA, et al: Phenothiazine-induced dyskinesia in nursinghome patients . J Amer Geriat Soc 16:27-34, 1968. 23. Delay J, Deniker P, Dalle B, et al: Syndrome choreique idiopathique rappelant la sémiologie d' imprégnation chronique par les neuroleptiques . Ann Medicopsych 125:784-788, 1967. 24. Paulson GW: An evaluation of the permanence of the "tardive dyskinesias." Dis Nerv Syst 29:692-694, 1968. 25. Degwitz R: in discussion, Psychotropic Drugs and Dysfunctions of the Basal Ganglia , bulletin 1938, Public Health Service, 1969, p 32. 26. Baker AB: in discussion, Degwitz R: Psychotropic Drugs and Dysfunctions of the Basal Ganglia , bulletin 1938, Public Health Service, 1969, p 29, 44. 27. Demars J: Neuromuscular effects of longterm phenothiazine medication, electroconvulsive therapy and leucotomy . J Nerv Ment Dis 143:73-79, 1966.Crossref 28. Melvin KEW: Tetanus-like reactions of the phenothiazine drugs, "The Grimacing Syndrome." New Zeal Med J 61:90-92, 1962. 29. Carpenter MB: Brain stem nuclei in studies of experimental dyskinesia . J Neurosurg 24( (suppl) ): 185-190, 1966. 30. Hughes B: Involuntary movements following stereotaxic operations for parkinsonism with special reference to hemichorea (ballismus) . J Neurol Neurosurg Psychiat 28:291-303, 1965.Crossref 31. Van Buren JM: in discussion, Degwitz R: Psychotropic Drugs and Dysfunctions of the Basal Ganglia , bulletin 1938, Public Health Service, 1969, p 169. 32. Papavasiliou P: in discussion, Psychotropic Drugs and Dysfunctions of the Basal Ganglia , bulletin 1938, Public Health Service, 1969, p 145. 33. Dill RE, Nickey WM, Little MD: Dyskinesias in rats following chemical stimulation of the neostriatum . Texas Rep Biol Med 26:101-106, 1968. 34. Nashold BS, Slaughter DG: Effects of stimulating or destroying deep cerebellar regions in man . J Neurosurg 31:172-186, 1969.Crossref 35. Nashold BS: The effects of central tegmental lesions on tardive dyskinesia , in Degwitz R: Psychotropic Drugs and Dsyfunctions of the Basal Ganglia , bulletin 1938, Public Health Service, 1969. 36. Christensen E, Moller JE, Faurbye A: Neuropathological investigation of 28 brains from patients with dyskinesia . Acta Psychiat Scand 46:14-23, 1970.Crossref 37. Cammermeyer, J: Neuropathological study of rhesus chronically treated with chlorpromazine , in Degwitz R: Psychotropic Drugs and Dysfunctions of the Basal Ganglia , bulletin 1938, Public Health Service, 1969, pp 19-20.
Archives of Neurology – American Medical Association
Published: Jun 1, 1972
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