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Personality (MMPI) and Cognitive (WAIS) Changes After Levodopa Treatment: Occurrence in Patients With Parkinson's Disease

Personality (MMPI) and Cognitive (WAIS) Changes After Levodopa Treatment: Occurrence in Patients... Abstract A group of patients receiving levodopa was given psychometric (Wechsler Adult Intelligence Scale) and personality (Minnesota Multiphasic Personality Inventory [MMPI]) measures at one and six months, and then were compared with a control group who had received traditional treatment (anticholinergic drugs and/or thalamotomies) over a similar time period. Generally, on the Wechsler intelligence quotients test patient performances on the control group declined, and performances on the levodopa group improved. Practical and statistically significant group differences were obtained on verbal (9.6 IQ points), performance (7.7), and full scale (9.0) IQ's at six months. No consistent group differences over the six-month period were obtained on the MMPI, but the typical elevation of scale 3 (depression) found on neurologically impaired patients occurred. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Neurology American Medical Association

Personality (MMPI) and Cognitive (WAIS) Changes After Levodopa Treatment: Occurrence in Patients With Parkinson's Disease

Archives of Neurology , Volume 25 (2) – Aug 1, 1971

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Publisher
American Medical Association
Copyright
Copyright © 1971 American Medical Association. All Rights Reserved.
ISSN
0003-9942
eISSN
1538-3687
DOI
10.1001/archneur.1971.00490020063007
Publisher site
See Article on Publisher Site

Abstract

Abstract A group of patients receiving levodopa was given psychometric (Wechsler Adult Intelligence Scale) and personality (Minnesota Multiphasic Personality Inventory [MMPI]) measures at one and six months, and then were compared with a control group who had received traditional treatment (anticholinergic drugs and/or thalamotomies) over a similar time period. Generally, on the Wechsler intelligence quotients test patient performances on the control group declined, and performances on the levodopa group improved. Practical and statistically significant group differences were obtained on verbal (9.6 IQ points), performance (7.7), and full scale (9.0) IQ's at six months. No consistent group differences over the six-month period were obtained on the MMPI, but the typical elevation of scale 3 (depression) found on neurologically impaired patients occurred.

Journal

Archives of NeurologyAmerican Medical Association

Published: Aug 1, 1971

There are no references for this article.