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Regional Cerebral Blood Flow in Man: II. Data Acquisition and Analysis

Regional Cerebral Blood Flow in Man: II. Data Acquisition and Analysis Abstract THE COMPLEXITY of data retrieval and burdensome calculations have limited the wide-spread application of the multiprobe inert gas method to the clinical assessment of regional cerebral blood flow (rCBF). Lassen1 has attempted to overcome this obstacle by observing the analogue readout of the early curve slope as an index of rCBF. Their approach is far simpler than previously described hand or computer calculations.2 However, the analogue method is limited by providing only a flow index rather than calculated rCBF in cc/100 gm/min and by its emphasis of fast flow (cortical) components to the exclusion of white matter flow. This simplified (analogue) modification has been most useful in studying regional autoregulation by observing the early slope before and after the induction of systemic hypertension. In developing a clinical method to obtain rCBF as an adjunct to carotid arteriography, we considered that it might not be desirable to References 1. Lassen, N.A.: Preliminary Experience With Oscilloscope and Polaroid Camera as Recorder Unit in a Multichannel Scintillation Detector Instrument , Scand J Lab Clin Invest , (suppl 102) , 1968. 2. Sveinsdottir, E.: " Clearance Curves of 85Kr or 133Xe Considered as a Sum of Mono-exponential Outwash Functions " in Ingvar, D., and Lassen, N.A. (eds.): Regional Cerebral Blood Flow , Copenhagen: Munksgaard, 1965, pp 69-71 3. Clifton, J.; Potchen, E.J.; and Hill, R.: A Digital Data Acquisition System for Nuclear Medicine , Intern J Appl Radiat 19:505-509 ( (June) ) 1968.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Neurology American Medical Association

Regional Cerebral Blood Flow in Man: II. Data Acquisition and Analysis

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References (4)

Publisher
American Medical Association
Copyright
Copyright © 1969 American Medical Association. All Rights Reserved.
ISSN
0003-9942
eISSN
1538-3687
DOI
10.1001/archneur.1969.00480100060009
Publisher site
See Article on Publisher Site

Abstract

Abstract THE COMPLEXITY of data retrieval and burdensome calculations have limited the wide-spread application of the multiprobe inert gas method to the clinical assessment of regional cerebral blood flow (rCBF). Lassen1 has attempted to overcome this obstacle by observing the analogue readout of the early curve slope as an index of rCBF. Their approach is far simpler than previously described hand or computer calculations.2 However, the analogue method is limited by providing only a flow index rather than calculated rCBF in cc/100 gm/min and by its emphasis of fast flow (cortical) components to the exclusion of white matter flow. This simplified (analogue) modification has been most useful in studying regional autoregulation by observing the early slope before and after the induction of systemic hypertension. In developing a clinical method to obtain rCBF as an adjunct to carotid arteriography, we considered that it might not be desirable to References 1. Lassen, N.A.: Preliminary Experience With Oscilloscope and Polaroid Camera as Recorder Unit in a Multichannel Scintillation Detector Instrument , Scand J Lab Clin Invest , (suppl 102) , 1968. 2. Sveinsdottir, E.: " Clearance Curves of 85Kr or 133Xe Considered as a Sum of Mono-exponential Outwash Functions " in Ingvar, D., and Lassen, N.A. (eds.): Regional Cerebral Blood Flow , Copenhagen: Munksgaard, 1965, pp 69-71 3. Clifton, J.; Potchen, E.J.; and Hill, R.: A Digital Data Acquisition System for Nuclear Medicine , Intern J Appl Radiat 19:505-509 ( (June) ) 1968.Crossref

Journal

Archives of Neurology – American Medical Association

Published: Apr 1, 1969

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