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F. Mettler (1964)
SUBSTANTIA NIGRA AND PARKINSONISM.Archives of neurology, 11
R. Carrea, F. Mettler (1954)
The anatomy of the primate brachium conjunctivum and associated structuresJournal of Comparative Neurology, 101
Mettler Fa (1965)
Evolution and subsidence of experimental tremor produced by mesencephalic lesion.Transactions of the American Neurological Association, 90
R. Carrea, F. Mettler (1955)
Function of the primate brachium conjunctivum and related structuresJournal of Comparative Neurology, 102
Mettler Fa (1946)
The experimental production of static tremor., 5
A. Ward, W. McCulloch, H. Magoun (1948)
Production of an alternating tremor at rest in monkeys.Journal of neurophysiology, 11 4
R. Carrea, F. Mettler (1947)
Physiologic consequences followiing extensive removals of the cerebellar cortex and deep cerebellar nuclei and effect of secondary cerebral ablations in the primateJournal of Comparative Neurology, 87
B. Boshes (1966)
DiscussionTrans Amer Neurol Assoc, 90
L. Poirier (1960)
Experimental and histological study of midbrain dyskinesias.Journal of neurophysiology, 23
R. Carrea (1954)
The Anatomy of the Primate Brachium ConjunctivumJ Comp Neurol, 101
A. Walker, H. Richter (1966)
Section of the cerebral peduncle in the monkey.Archives of neurology, 14 3
F.A. Mettler (1965)
Temporal Evolution of Experimentally Produced Static TremorFed Proc, 24
F.A. Mettler (1965)
Mesencephalic Focus Responsible for TremorAnat Rec, 151
Abstract TREMOR, resembling that seen in parkinsonism, can be produced by placing a lesion in the ventromedial mesencephalic quadrant. The structures which need to be involved in such an approach and their relative importance have been described in a number of earlier communications.1-4 The fact that such tremor takes some time to mature and tends to change its character with the passage of time limits its utility as a paradigm for research in parkinsonism. The principle of temporal change has, however, important implications for an understanding of the etiology of that common clinical disorder. The principle of significant dimension in time is not limited to tremor but can be found in other types of symptomatology, such as lid retraction, and occurs following a wide variety of types of initial "causes." A time lag after the onset of the supposed etiologic process in some patients with parkinsonism has long been known. References 1. Mettler, F.A.: Experimental Production of Static Tremor , Fed Proc 5:72, 1946. 2. Carrea, R.M.E., and Mettler, F.A.: Physiologic Consequences Following Extensive Removals of Cerebellar Cortex and Deep Cerebellar Nuclei and Effect of Secondary Cerebral Ablations in Primate , J Comp Neurol 87:169, 1947.Crossref 3. Ward, A.A.; McCulloch, W.S.; and Magoun, H.W.: Production of Alterating Tremor at Rest in Monkeys , J Neurophysiol 11:317, 1948. 4. Poirier, L.J.: Experimental and Histological Study of Midbrain Dyskinesias , J Neurophysiol 23:534, 1960. 5. Pasik, P.: Discussion , Trans Amer Neurol Assoc 90:174, 1965. 6. Carrea, R., and Mettler, F.A.: The Anatomy of the Primate Brachium Conjunctivum , J Comp Neurol 101:565, 1954.Crossref 7. Carrea, R., and Mettler, F.A.: Function of the Primate Brachium Conjunctivum and Related Structures , J Comp Neurol 102:151, 1955.Crossref 8. Mettler, F.A.: Substantia Nigra and Parkinsonism , Arch Neurol 11:529, 1964.Crossref 9. Denny-Brown, D.: Discussion , Trans Amer Neurol Assoc 90:172, 1965. 10. Trétiakoff, C.: Contribution á l'étude de l'anatomie pathologique du locus niger de Soemmering avec quelques déductions rélatives a la pathogénie des troubles du tonus musculaire de la maladie de Parkinson, thesis 293, Paris, 1919. 11. Boshes, B.: Discussion , Trans Amer Neurol Assoc 90:174, 1966. 12. Walker, A.E., and Richter, H.: Section of the Cerebral Peduncle in the Monkey , Arch Neurol 14:231, 1966.Crossref 13. Mettler, F.A.: Substantia Nigra and Parkinsonism , Arch Neurol 11:529, 1964.Crossref 14. Mettler, F.A.: Mesencephalic Focus Responsible for Tremor , Anat Rec 151:499, 1965. 15. Mettler, F.A.: Temporal Evolution of Experimentally Produced Static Tremor , Fed Proc 24:646, 1965. 16. Mettler, F.A.: Evolution and Subsidence of Experimental Tremor Produced by Mesencephalic Lesion , Trans Amer Neurol Assoc 90:171, 1965.
Archives of Neurology – American Medical Association
Published: Sep 1, 1966
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