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Exposure to Particulate Air Pollution and Cognitive Decline in Older Women

Exposure to Particulate Air Pollution and Cognitive Decline in Older Women ORIGINAL INVESTIGATION Exposure to Particulate Air Pollution and Cognitive Decline in Older Women Jennifer Weuve, MPH, ScD; Robin C. Puett, MPH, PhD; Joel Schwartz, PhD; Jeff D. Yanosky, MS, ScD; Francine Laden, MS, ScD; Francine Grodstein, ScD Background: Chronic exposure to particulate air pol- ing tests of general cognition, verbal memory, category fluency, working memory, and attention. lution may accelerate cognitive decline in older adults, although data on this association are limited. Our objec- Results: Higher levels of long-term exposure to both tive was to examine long-term exposure to particulate PM and PM were associated with significantly faster matter (PM) air pollution, both coarse ([PM 2.5-10 µm 2.5-10 2.5 cognitive decline. Two-year decline on a global score was in diameter [PM ]) and fine (PM 2.5 µm in diam- 2.5-10 0.020 (95% CI, −0.032 to −0.008) standard units worse eter [PM ]), in relation to cognitive decline. 2.5 per 10 µg/m increment in PM exposure and 0.018 2.5-10 (95% CI, −0.035 to −0.002) units worse per 10 µg/m in- Methods: The study population comprised the Nurses’ crement in PM exposure. These differences in cogni- 2.5 Health Study Cognitive Cohort, which included 19 409 tive trajectory were similar to those http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Internal Medicine American Medical Association

Exposure to Particulate Air Pollution and Cognitive Decline in Older Women

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References (59)

Publisher
American Medical Association
Copyright
Copyright 2012 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6106
eISSN
2168-6114
DOI
10.1001/archinternmed.2011.683
pmid
22332151
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL INVESTIGATION Exposure to Particulate Air Pollution and Cognitive Decline in Older Women Jennifer Weuve, MPH, ScD; Robin C. Puett, MPH, PhD; Joel Schwartz, PhD; Jeff D. Yanosky, MS, ScD; Francine Laden, MS, ScD; Francine Grodstein, ScD Background: Chronic exposure to particulate air pol- ing tests of general cognition, verbal memory, category fluency, working memory, and attention. lution may accelerate cognitive decline in older adults, although data on this association are limited. Our objec- Results: Higher levels of long-term exposure to both tive was to examine long-term exposure to particulate PM and PM were associated with significantly faster matter (PM) air pollution, both coarse ([PM 2.5-10 µm 2.5-10 2.5 cognitive decline. Two-year decline on a global score was in diameter [PM ]) and fine (PM 2.5 µm in diam- 2.5-10 0.020 (95% CI, −0.032 to −0.008) standard units worse eter [PM ]), in relation to cognitive decline. 2.5 per 10 µg/m increment in PM exposure and 0.018 2.5-10 (95% CI, −0.035 to −0.002) units worse per 10 µg/m in- Methods: The study population comprised the Nurses’ crement in PM exposure. These differences in cogni- 2.5 Health Study Cognitive Cohort, which included 19 409 tive trajectory were similar to those

Journal

JAMA Internal Medicine – American Medical Association

Published: Feb 13, 2012

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