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ORIGINAL INVESTIGATION LESS IS MORE Trends in Timing of Initiation of Chronic Dialysis in the United States Ann M. O’Hare, MD, MA; Andy I. Choi, MD, MS†; W. John Boscardin, PhD; Walter L. Clinton, PhD; Ilan Zawadzki, MD; Paul L. Hebert, PhD; Manjula Kurella Tamura, MD, MPH; Leslie Taylor, PhD; Eric B. Larson, MD, MPH Background: During the past decade, a trend has been istics of new US dialysis patients from 1997 to 2007, we observed in the United States toward initiation of chronic estimate that chronic dialysis was initiated a mean of 147 dialysis at higher levels of estimated glomerular filtration days earlier (95% confidence interval, 134-160) in the rate. This likely reflects secular trends in the composition later compared with the earlier year. Differences in tim- ing were consistent across a range of patient subgroups of the dialysis population and a tendency toward initia- but were most pronounced for those aged 75 years or tion of dialysis earlier in the course of kidney disease. older; the mean difference in timing in that subgroup was 233 days (95% confidence interval, 206-267). Methods: The goal of this study was to generate model- based estimates of the magnitude of changes
JAMA Internal Medicine – American Medical Association
Published: Oct 10, 2011
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