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Incidental Findings in Imaging Research

Incidental Findings in Imaging Research ORIGINAL INVESTIGATION Evaluating Incidence, Benefit, and Burden Nicholas M. Orme, MD; Joel G. Fletcher, MD; Hassan A. Siddiki, MBBS; W. Scott Harmsen, MS; Megan M. O’Byrne, MA; John D. Port, MD, PhD; William J. Tremaine, MD; Henry C. Pitot, MD; Elizabeth G. McFarland, MD; Marguerite E. Robinson, MAR, MA; Barbara A. Koenig, PhD; Bernard F. King, MD; Susan M. Wolf, JD Background: Little information exists concerning the 9.2% with subsequent clinical action), with computed to- frequency and medical significance of incidental find- mography of the thorax and magnetic resonance imaging ings (IFs) in imaging research. of the head next (OR, 11.9 and 5.9; 2.8% and 2.2% with action, respectively). Of the 567 examinations with an Methods: Medical records of research participants un- IF, 35 (6.2%) generated clinical action, resulting in clear dergoing a research imaging examination interpreted by medical benefit in 1.1% (6 of 567) and clear medical bur- a radiologist during January through March 2004 were den in 0.5% (3 of 567). Medical benefit/burden was usu- reviewed, with 3-year clinical follow-up. An expert panel ally unclear (26 of 567 [4.6%]). reviewed all IFs generating clinical action to determine medical benefit/burden on the basis of predefined crite- Conclusions: Frequency http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Internal Medicine American Medical Association

Incidental Findings in Imaging Research

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References (26)

Publisher
American Medical Association
Copyright
Copyright 2010 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6106
eISSN
2168-6114
DOI
10.1001/archinternmed.2010.317
pmid
20876402
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL INVESTIGATION Evaluating Incidence, Benefit, and Burden Nicholas M. Orme, MD; Joel G. Fletcher, MD; Hassan A. Siddiki, MBBS; W. Scott Harmsen, MS; Megan M. O’Byrne, MA; John D. Port, MD, PhD; William J. Tremaine, MD; Henry C. Pitot, MD; Elizabeth G. McFarland, MD; Marguerite E. Robinson, MAR, MA; Barbara A. Koenig, PhD; Bernard F. King, MD; Susan M. Wolf, JD Background: Little information exists concerning the 9.2% with subsequent clinical action), with computed to- frequency and medical significance of incidental find- mography of the thorax and magnetic resonance imaging ings (IFs) in imaging research. of the head next (OR, 11.9 and 5.9; 2.8% and 2.2% with action, respectively). Of the 567 examinations with an Methods: Medical records of research participants un- IF, 35 (6.2%) generated clinical action, resulting in clear dergoing a research imaging examination interpreted by medical benefit in 1.1% (6 of 567) and clear medical bur- a radiologist during January through March 2004 were den in 0.5% (3 of 567). Medical benefit/burden was usu- reviewed, with 3-year clinical follow-up. An expert panel ally unclear (26 of 567 [4.6%]). reviewed all IFs generating clinical action to determine medical benefit/burden on the basis of predefined crite- Conclusions: Frequency

Journal

JAMA Internal Medicine – American Medical Association

Published: Sep 27, 2010

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