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ORIGINAL INVESTIGATION Effect of a Pharmacist on Adverse Drug Events and Medication Errors in Outpatients With Cardiovascular Disease Michael D. Murray, PharmD, MPH; Mary E. Ritchey, RN, MSPH; Jingwei Wu, MS; Wanzhu Tu, PhD Background: Adverse drug events and medication er- spectively, at 12 months. Compared with the control rors are threats to quality care. Inpatient studies suggest group, the risk of any event was 34% lower in the inter- that a pharmacist may reduce these events, but outpa- vention group (risk ratio, 0.66; 95% confidence interval tient studies have not been forthcoming. [CI], 0.50-0.88), including a lower risk of adverse drug events (risk ratio, 0.65; 95% CI, 0.47-0.90), preventable Methods: We conducted a pooled analysis of 2 random- adverse drug events (risk ratio, 0.52; 95% CI, 0.25- ized controlled trials to determine the effect of pharma- 1.09), potential adverse drug events (risk ratio, 0.70; 95% cist intervention on adverse drug events and medication CI, 0.40-1.22), and medication errors (risk ratio, 0.63; errors. We studied 800 outpatient cases of hypertension 95% CI, 0.40-0.98). stratified into complicated (n = 535) and uncomplicated (n = 265). Patients in the complicated stratum had heart Conclusions: This post hoc analysis suggests that phar-
JAMA Internal Medicine – American Medical Association
Published: Apr 27, 2009
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