Drug Interaction With Quinolone Antibiotics in Intensive Care Unit Patients
Abstract
Abstract To the Editor. — It is not uncommon for the patients in an intensive care unit (ICU) to become colonized with resistant organisms after a course of antibiotics. These organisms are frequently resistant to most antibiotics, and ciprofloxacin often becomes one of the few options for oral treatment. The majority of the patients in the ICU, however, also receive prophylactic antacid therapy to prevent stress ulcers. Despite the profound negative effect of antacids or sucralfate on...