Results of a Randomized Study of Clodronate in Treating Cancer-Related Hypercalcemia
Abstract
Abstract To the Editor. —The article by Witte and coworkers1 describing the results of a randomized study of clodronate in treating cancer-related hypercalcemia conveys erroneous information regarding the appearance of acute leukemia among subjects of a recent multicenter study. The authors state "the finding of three cases of acute leukemia in 664 patients, most of whom had received alkylating agents, caused the study sponsor (Proctor & Gamble Co, Cincinnati) to stop this...