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Korbet SM Corwin HL (1985)
Clinical correlates of eosinophiluria.Arch Intern Med, 145
Weidig J Norby LH (1979)
Possible role for impaired renal prostaglandin production in the pathogenesis of hyporeninaemic hypoaldosteronism.Lancet, 2
Chou SY Anto HR (1981)
Infusion intravenous pyelography and renal function: Effects of hypertonic mannitol in patients with chronic renal failure.Arch Intern Med, 141
Cinotti GA Ciabattoni G (1984)
Effects on sulindac and ibuprofen in patients with chronic glomerular disease: Evidence for the dependence of renal function on prostacyclin.N Engl J Med, 310
Gleason RE D'Elia J (1982)
Nephrotoxicity from angiographic contrast material: A prospective study.Am J Med, 72
Bennett WM (1983)
Aminoglycoside nephrotoxicity.Nephron, 35
Kjellstrand CM Berkseth RO (1984)
Radiologic contrast-induced nephropathy.Med Clin North Am, 68
Knaus TC Sastrasinh M (1982)
Identification of the aminoglycoside binding site of renal brush border membranes.J Pharmacol Exp Ther, 222
Shinaberger JH Galpin JE (1978)
Acute interstitial nephritis due to methicillin.Am J Med, 65
Widener LL Mela-Riker LM (1986)
Renal mitochondrial integrity during continuous gentamicin treatment.Biochem Pharmacol, 35
Smith CR Wade JC (1978)
Cephalothin plus an aminoglycoside is more nephrotoxic than methicillin plus an aminoglycoside.Lancet, 2
Moore RD Sawyers CL (1986)
A model for predicting nephrotoxicity in patients treated with aminoglycosides.J Infect Dis, 153
Currie JP Atkinson RM (1966)
Acute toxicity of cephaloridine, an antibiotic derived from cephalosporin C.Toxicol Appl Pharmacol, 8
Davidson AJ Talner LB (1968)
Renal hemodynamic effects of contrast media.Invest Radiol, 3
Shapiro R Tan SY (1979)
Indomethacin-induced prostaglandin inhibition with hyperkalemia: A reversible cause of hyporeninemic hypoaldosteronism.Ann Intern Med, 90
Hunt DA Humes HD (1987)
Direct toxic effect of the radiocontrast agent diatrizoate on renal proximal tubular cells.Am J Physiol, 21
Davidman M Blackshear JL (1983)
Identification of risk for renal insufficiency from nonsteroidal anti-inflammatory drugs.Arch Intern Med, 143
Bushinsky DA Hou SH (1983)
Hospital-acquired renal insufficiency: A prospective study.Am J Med, 74
Baughman KL Smith CR (1977)
Controlled comparison of amikacin and gentamicin.N Engl J Med, 296
Stoff JS Clive DM (1984)
Renal syndromes associated with nonsteroidal antiinflammatory drugs.N Engl J Med, 310
Rowe JW Gelman LM (1979)
Effects of an angiographic contrast agent on renal function.Cardiovasc Med, 4
Vane JR Aiken JW (1973)
Intrarenal prostaglandin release attenuated the renal vasoconstrictor activity of angiotensin.J Pharmacol Exp Ther, 184
Lipsky JJ Smith CR (1980)
Double-blind comparison of the nephrotoxicity and auditory toxicity of gentamicin and tobramycin.N Engl J Med, 302
Guiliano RA DeBroe M (1986)
Choice of drug and dosage regimen: Two important risk factors for aminoglycoside nephrotoxicity.Am J Med, 80
Weinberg JM Humes HD (1986)
The Kidney
Vlietstra RE Taliercio CP (1986)
Risks for renal dysfunction with cardiac angiography.AJR, 104
Aisenbrey GA Lum GM (1977)
In vivo effect of indomethacin to potentiate the renal medullary cyclic AMP response to vasopressin.J Clin Invest, 59
Kjellstrand C Harkonen S (1981)
Contrast nephropathy.Am J Nephrol, 1
Katz SM Brezin JH (1979)
Reversible renal failure and nephrotic syndrome associated with nonsteroidal anti-inflammatory drugs.N Engl J Med, 301
Ward M Hart D (1987)
Suprofen-related nephrotoxicity: A distinct clinical syndrome.Ann Intern Med, 106
Anger MS Nolan CR (1986)
Eosinophiluria: A new method of detection and definition of the clinical spectrum.N Engl J Med, 315
L'Eorme M (1986)
Nonsteroidal anti-inflammatory drugs and the kidney.Br Med J, 2
Sirota RA Fang LS (1980)
Low fractional excretion of sodium with contrast media—induced acute renal failure.Arch Intern Med, 140
Kelley WN Postlewaite AE (1971)
Uricosuric effect of radiocontrast agents.Ann Intern Med, 74
Hoy WE Van Zee BE (1978)
Renal injury associated with intravenous pyelography in nondiabetic and diabetic patients.Ann Intern Med, 89
Clark WF Linton AL (1980)
Acute interstitial nephritis due to drugs.Ann Intern Med, 93
Duarte CM Old CW (1981)
A prospective evaluation of mannitol in the prevention of radiocontrast acute renal failure, abstracted.Clin Res, 29
Abstract • Drug-induced nephrotoxicity is an increasingly recognized complication of a wide variety of therapeutic agents. The nephrotoxicity of three of the most commonly used drug groups are reviewed in this article. They include antibiotics, radiocontrast agents, and nonsteroidal anti-inflammatory drugs. Since the clinical spectrum of drug-induced nephrotoxicity is broad, it is imperative that the clinician recognize these nephrotoxic syndromes while they are reversible with discontinuation of the offending drug. (Arch Intern Med 1987;147:1213-1218) References 1. Hou SH, Bushinsky DA, Wish JB, et al: Hospital-acquired renal insufficiency: A prospective study. Am J Med 1983;74:243-248.Crossref 2. Humes HD, Weinberg JM: Toxic nephropathies , in Brenner BM, Rector FC (eds): The Kidney . Philadelphia, WB Saunders Co, 1986. 3. Smith CR, Lipsky JJ, Laskin OL, et al: Double-blind comparison of the nephrotoxicity and auditory toxicity of gentamicin and tobramycin. N Engl J Med 1980;302:1106-1109.Crossref 4. Smith CR, Baughman KL, Edwards CQ, et al: Controlled comparison of amikacin and gentamicin. N Engl J Med 1977;296:349-354.Crossref 5. Bennett WM: Aminoglycoside nephrotoxicity. Nephron 1983;35:73-77.Crossref 6. Sastrasinh M, Knaus TC, Winberg JM, et al: Identification of the aminoglycoside binding site of renal brush border membranes. J Pharmacol Exp Ther 1982;222:350-358. 7. Mela-Riker LM, Widener LL, Houghton DC, et al: Renal mitochondrial integrity during continuous gentamicin treatment. Biochem Pharmacol 1986;35:979-984.Crossref 8. DeBroe M, Guiliano RA, Verpooten GA: Choice of drug and dosage regimen: Two important risk factors for aminoglycoside nephrotoxicity. Am J Med 1986;80:115-118.Crossref 9. Sawyers CL, Moore RD, Lerner SA, et al: A model for predicting nephrotoxicity in patients treated with aminoglycosides. J Infect Dis 1986;153:1062-1068.Crossref 10. Wade JC, Smith CR, Petty BG, et al: Cephalothin plus an aminoglycoside is more nephrotoxic than methicillin plus an aminoglycoside. Lancet 1978;2:604-606.Crossref 11. Atkinson RM, Currie JP, Davis B, et al: Acute toxicity of cephaloridine, an antibiotic derived from cephalosporin C. Toxicol Appl Pharmacol 1966;8:398-406.Crossref 12. Corwin HL, Korbet SM, Schwartz MM: Clinical correlates of eosinophiluria. Arch Intern Med 1985;145:1097-1099.Crossref 13. Nolan CR, Anger MS, Kelleher SP: Eosinophiluria: A new method of detection and definition of the clinical spectrum. N Engl J Med 1986;315: 1516-1519.Crossref 14. Linton AL, Clark WF, Driedger AA, et al: Acute interstitial nephritis due to drugs. Ann Intern Med 1980;93:735-741.Crossref 15. Galpin JE, Shinaberger JH, Stanley TM, et al: Acute interstitial nephritis due to methicillin. Am J Med 1978;65:756-765.Crossref 16. Berkseth RO, Kjellstrand CM: Radiologic contrast-induced nephropathy. Med Clin North Am 1984;68:351-370. 17. Talner LB, Davidson AJ: Renal hemodynamic effects of contrast media. Invest Radiol 1968;3:310-317.Crossref 18. Fang LS, Sirota RA, Ebert TH, et al: Low fractional excretion of sodium with contrast media—induced acute renal failure. Arch Intern Med 1980;140:531-533.Crossref 19. Humes HD, Hunt DA, White MD: Direct toxic effect of the radiocontrast agent diatrizoate on renal proximal tubular cells. Am J Physiol 1987;21:F246-F255. 20. Postlewaite AE, Kelley WN: Uricosuric effect of radiocontrast agents. Ann Intern Med 1971;74:845-852.Crossref 21. Gelman LM, Rowe JW, Coggins CH: Effects of an angiographic contrast agent on renal function. Cardiovasc Med 1979;4:313-320. 22. Harkonen S, Kjellstrand C: Contrast nephropathy. Am J Nephrol 1981;1:69.Crossref 23. Van Zee BE, Hoy WE, Talley TE, et al: Renal injury associated with intravenous pyelography in nondiabetic and diabetic patients. Ann Intern Med 1978;89:51-54.Crossref 24. D'Elia J, Gleason RE, Alday M, et al: Nephrotoxicity from angiographic contrast material: A prospective study. Am J Med 1982;72: 719-725.Crossref 25. Taliercio CP, Vlietstra RE, Fisher LD, et al: Risks for renal dysfunction with cardiac angiography. AJR 1986;104:501-504. 26. Anto HR, Chou SY, Porush JC, et al: Infusion intravenous pyelography and renal function: Effects of hypertonic mannitol in patients with chronic renal failure. Arch Intern Med 1981;141:1652-1656.Crossref 27. Old CW, Duarte CM, Lehrner LM, et al: A prospective evaluation of mannitol in the prevention of radiocontrast acute renal failure, abstracted. Clin Res 1981;29:472A. 28. L'Eorme M: Nonsteroidal anti-inflammatory drugs and the kidney. Br Med J 1986;2:1621-1622.Crossref 29. Blackshear JL, Davidman M, Stillman MT: Identification of risk for renal insufficiency from nonsteroidal anti-inflammatory drugs. Arch Intern Med 1983;143:1130-1134.Crossref 30. Clive DM, Stoff JS: Renal syndromes associated with nonsteroidal antiinflammatory drugs. N Engl J Med 1984;310:563-572.Crossref 31. Aiken JW, Vane JR: Intrarenal prostaglandin release attenuated the renal vasoconstrictor activity of angiotensin. J Pharmacol Exp Ther 1973;184:678-687. 32. Ciabattoni G, Cinotti GA, Pierucci A, et al: Effects on sulindac and ibuprofen in patients with chronic glomerular disease: Evidence for the dependence of renal function on prostacyclin. N Engl J Med 1984;310: 279-283.Crossref 33. Brezin JH, Katz SM, Schwartz AB, et al: Reversible renal failure and nephrotic syndrome associated with nonsteroidal anti-inflammatory drugs. N Engl J Med 1979;301:1271-1273.Crossref 34. Norby LH, Weidig J, Ranwell P, et al: Possible role for impaired renal prostaglandin production in the pathogenesis of hyporeninaemic hypoaldosteronism. Lancet 1979;2:1118. 35. Tan SY, Shapiro R, Franco R, et al: Indomethacin-induced prostaglandin inhibition with hyperkalemia: A reversible cause of hyporeninemic hypoaldosteronism. Ann Intern Med 1979;90:783-785.Crossref 36. Lum GM, Aisenbrey GA, Dunn MJ, et al: In vivo effect of indomethacin to potentiate the renal medullary cyclic AMP response to vasopressin. J Clin Invest 1977;59:8-13.Crossref 37. Hart D, Ward M, Lifschitz M: Suprofen-related nephrotoxicity: A distinct clinical syndrome. Ann Intern Med 1987;106:235-238.Crossref
Archives of Internal Medicine – American Medical Association
Published: Jul 1, 1987
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