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Thallium 201 Myocardial Scintigraphy: Advantages and Limitations

Thallium 201 Myocardial Scintigraphy: Advantages and Limitations Abstract • Myocardial scintigraphy with thallium 201 is a simple, safe, and valuable noninvasive technique in evaluating the condition of patients with cardiac disorders. Images obtained at rest appear to have limited usefulness at the present time. However, rest imaging may prove to have advantages in the future for early diagnosis of myocardial infarction, thus aiding in the selection of patients to be admitted to the coronary care unit. Exercise imaging, on the other hand, has a high degree of sensitivity and specificity in detecting ischemic heart disease; when combined with treadmill exercise testing, imaging improves the diagnostic accuracy even further. (Arch Intern Med 140:320-327, 1980) References 1. Strauss HW, Harrison K, Langan JK, et al: Thallium-201 for myocardial imaging: Relation of thallium-201 to regional myocardial perfusion. Circulation 51:641-645, 1975.Crossref 2. Hamilton GW, Narahara KA, Yee H, et al: Myocardial imaging with thallium-201: Effect of cardiac drugs on myocardial images and absolute tissue distribution. J Nucl Med 19:10-16, 1978. 3. Gewirtz H, O'Keefe DD, Pohost GM, et al: The effect of ischemia on thallium-201 clearance from the myocardium. Circulation 58:215-219, 1978.Crossref 4. Mueller TM, Marcus ML, Ehrhardt JC, et al: Limitations of thallium201 myocardial perfusion scintigrams. Circulation 54:640-646, 1976.Crossref 5. Wackers FJTh, Sokole EB, Samson G, et al: Value and limitations of thallium-201 scintigraphy in the acute phase of myocardial infarction. N Engl J Med 295:1-5, 1976.Crossref 6. Smitherman TC, Osborn RC, Narahara KA: Serial myocardial scintigraphy after a single dose of thallium-201 in men after acute myocardial infarction. Am J Cardiol 42:177-182, 1978.Crossref 7. Hamilton GW, Trobaugh GB, Ritchie JL, et al: Myocardial imaging with intravenously injected thallium-201 in patients with suspected coronary artery disease: Analysis of the technique and correlation with electrocardiographic, coronary anatomic and ventriculographic findings. Am J Cardiol 39:347-354, 1977.Crossref 8. Wackers FJTh, Becker AE, Samson G, et al: Location and size of acute transmural infarction estimated from thallium-201 scintiscans: A clinicopathological study. Circulation 56:72-78, 1977.Crossref 9. Niess GS, Logic JR, Russell RO Jr, et al: Usefulness and limitations of thallium-201 myocardial scintigraphy in delineating location and size of prior myocardial infarction. Circulation 59:1010-1019, 1979.Crossref 10. Berger HJ, Gottschalk A, Zaret BL: Dual radionuclide study of acute myocardial infarction: Comparison of thallium-201 and technetium-99m stannous pyrophosphate imaging in man. Ann Intern Med 88:145-154, 1978.Crossref 11. Gewirtz H, Beller GA, Strauss HW, et al: Transient defects on resting thallium scans in patients with coronary artery disease. Circulation 59:707-713, 1979.Crossref 12. Kondo M, Kubo A, Yamazaki H, et al: Thallium-201 myocardial imaging for evaluation of right ventricular overloading. J Nucl Med 19:1197-1203, 1978. 13. Bulkley BH, Rouleau J, Whitaker JQ, et al: The use of 201-thallium for mvocardial perfusion imaging in sarcoid heart disease. Chest 72:27-32, 1977.Crossref 14. Finley JP, Howman-Giles R, Gilday DL, et al: Thallium-201 myocardial imaging in anomalous left coronary artery arising from the pulmonary artery. Am J Cardiol 42:675-680, 1978.Crossref 15. Pohost GM, Zir LM, Moore RH, et al: Differentiation of transiently ischemie from infarcted myocardium by serial imaging after a single dose of thallium-201. Circulation 55:294-302, 1977.Crossref 16. Blood DK, McCarthy DM, Sciacca RR, et al: Comparison of single-dose and double-dose thallium-201 myocardial perfusion scintigraphy for the detection of coronary artery disease and prior myocardial infarction. Circulation 58:777-788, 1978.Crossref 17. Botvinick EH, Taradash MR, Shames DM, et al: Thallium-201 myocardial perfusion scintigraphy for the clinical clarification of normal, abnormal, and equivocal electrocardiographic stress tests. Am J Cardiol 41:43-51, 1978.Crossref 18. McCarthy DM, Blood DR, Sciacca RR, et al: Single-dose myocardial perfusion imaging with thallium-201: Application in patients with nondiagnostic electrocardiographic stress tests. Am J Cardiol 43:899-906, 1979.Crossref 19. Ritchie JL, Trobaugh GB, Hamilton GW, et al: Myocardial imaging with thallium-201 at rest and during exercise: Comparison with coronary arteriography and resting and stress electrocardiography. Circulation 56:66-71, 1977.Crossref 20. Carrillo AP, Marks DS, Pickard SD, et al: Correlation of exercise 201thallium myocardial scan with coronary arteriograms and the maximal exercise test. Chest 73:321-326, 1978.Crossref 21. Verani MS, Marcus ML, Razzak MA, et al: Sensitivity and specificity of thallium-201 perfusion scintigrams under exercise in diagnosis of coronary artery disease. J Nucl Med 19:773-782, 1978. 22. Bailey IK, Griffith LSC, Rouleau J, et al: Thallium-201 myocardial perfusion imaging at rest and during exercise: Comparative sensitivity to electrocardiography in coronary artery disease. Circulation 55:79-87, 1977.Crossref 23. Iskandrian AS, Mintz GS, Croll MN, et al: Exercise thallium-201 myocardial scintigraphy: Advantages and limitations. Cardiology , to be published. 24. Gaffney FA, Wohl AJ, Blomquist CG, et al: Thallium-201 myocardial perfusion studies in patients with the mitral valve prolapse syndrome. Am J Med 64:21-26, 1978.Crossref 25. Bailey IK, Come PC, Kelley DT, et al: Thallium-201 myocardial perfusion imaging in aortic valve stenosis. Am J Cardiol 40:889-898, 1977.Crossref 26. Massie BM, Botvinick EH, Brundage BH, et al: Relationship of regional myocardial perfusion to segmental wall motion: A physiologic basis for understanding the presence and reversibility of asynergy. Circulation 58:1154-1162, 1978.Crossref 27. Greenberg BH, Hart R, Botvinick EH, et al: Thallium-201 myocardial perfusion scintigraphy to evaluate patients after coronary bypass surgery. Am J Cardiol 42:167-176, 1978.Crossref 28. Albro PC, Gould KL, Westcott RJ, et al: Noninvasive assessment of coronary stenosis by myocardial imaging during pharmacologic coronary vasodilatation: III. Clinical trials. Am J Cardiol 42:751-760, 1978.Crossref 29. Vogel RA, Kirch DL, Lee Free MT, et al: Thallium-201 myocardial perfusion scintigraphy: Results of standard and multi-pinhole tomographic technique. Am J Cardiol 43:787-791, 1979.Crossref 30. Iskandrian AS, Scherer H, Croll MN, et al: Exercise thallium-201 myocardial scans in patients with disease limited to the secondary branches of the left coronary system. Clin Cardiol 2:121-125, 1979.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

Thallium 201 Myocardial Scintigraphy: Advantages and Limitations

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References (34)

Publisher
American Medical Association
Copyright
Copyright © 1980 American Medical Association. All Rights Reserved.
ISSN
0003-9926
eISSN
1538-3679
DOI
10.1001/archinte.1980.00330150034013
Publisher site
See Article on Publisher Site

Abstract

Abstract • Myocardial scintigraphy with thallium 201 is a simple, safe, and valuable noninvasive technique in evaluating the condition of patients with cardiac disorders. Images obtained at rest appear to have limited usefulness at the present time. However, rest imaging may prove to have advantages in the future for early diagnosis of myocardial infarction, thus aiding in the selection of patients to be admitted to the coronary care unit. Exercise imaging, on the other hand, has a high degree of sensitivity and specificity in detecting ischemic heart disease; when combined with treadmill exercise testing, imaging improves the diagnostic accuracy even further. (Arch Intern Med 140:320-327, 1980) References 1. Strauss HW, Harrison K, Langan JK, et al: Thallium-201 for myocardial imaging: Relation of thallium-201 to regional myocardial perfusion. Circulation 51:641-645, 1975.Crossref 2. Hamilton GW, Narahara KA, Yee H, et al: Myocardial imaging with thallium-201: Effect of cardiac drugs on myocardial images and absolute tissue distribution. J Nucl Med 19:10-16, 1978. 3. Gewirtz H, O'Keefe DD, Pohost GM, et al: The effect of ischemia on thallium-201 clearance from the myocardium. Circulation 58:215-219, 1978.Crossref 4. Mueller TM, Marcus ML, Ehrhardt JC, et al: Limitations of thallium201 myocardial perfusion scintigrams. Circulation 54:640-646, 1976.Crossref 5. Wackers FJTh, Sokole EB, Samson G, et al: Value and limitations of thallium-201 scintigraphy in the acute phase of myocardial infarction. N Engl J Med 295:1-5, 1976.Crossref 6. Smitherman TC, Osborn RC, Narahara KA: Serial myocardial scintigraphy after a single dose of thallium-201 in men after acute myocardial infarction. Am J Cardiol 42:177-182, 1978.Crossref 7. Hamilton GW, Trobaugh GB, Ritchie JL, et al: Myocardial imaging with intravenously injected thallium-201 in patients with suspected coronary artery disease: Analysis of the technique and correlation with electrocardiographic, coronary anatomic and ventriculographic findings. Am J Cardiol 39:347-354, 1977.Crossref 8. Wackers FJTh, Becker AE, Samson G, et al: Location and size of acute transmural infarction estimated from thallium-201 scintiscans: A clinicopathological study. Circulation 56:72-78, 1977.Crossref 9. Niess GS, Logic JR, Russell RO Jr, et al: Usefulness and limitations of thallium-201 myocardial scintigraphy in delineating location and size of prior myocardial infarction. Circulation 59:1010-1019, 1979.Crossref 10. Berger HJ, Gottschalk A, Zaret BL: Dual radionuclide study of acute myocardial infarction: Comparison of thallium-201 and technetium-99m stannous pyrophosphate imaging in man. Ann Intern Med 88:145-154, 1978.Crossref 11. Gewirtz H, Beller GA, Strauss HW, et al: Transient defects on resting thallium scans in patients with coronary artery disease. Circulation 59:707-713, 1979.Crossref 12. Kondo M, Kubo A, Yamazaki H, et al: Thallium-201 myocardial imaging for evaluation of right ventricular overloading. J Nucl Med 19:1197-1203, 1978. 13. Bulkley BH, Rouleau J, Whitaker JQ, et al: The use of 201-thallium for mvocardial perfusion imaging in sarcoid heart disease. Chest 72:27-32, 1977.Crossref 14. Finley JP, Howman-Giles R, Gilday DL, et al: Thallium-201 myocardial imaging in anomalous left coronary artery arising from the pulmonary artery. Am J Cardiol 42:675-680, 1978.Crossref 15. Pohost GM, Zir LM, Moore RH, et al: Differentiation of transiently ischemie from infarcted myocardium by serial imaging after a single dose of thallium-201. Circulation 55:294-302, 1977.Crossref 16. Blood DK, McCarthy DM, Sciacca RR, et al: Comparison of single-dose and double-dose thallium-201 myocardial perfusion scintigraphy for the detection of coronary artery disease and prior myocardial infarction. Circulation 58:777-788, 1978.Crossref 17. Botvinick EH, Taradash MR, Shames DM, et al: Thallium-201 myocardial perfusion scintigraphy for the clinical clarification of normal, abnormal, and equivocal electrocardiographic stress tests. Am J Cardiol 41:43-51, 1978.Crossref 18. McCarthy DM, Blood DR, Sciacca RR, et al: Single-dose myocardial perfusion imaging with thallium-201: Application in patients with nondiagnostic electrocardiographic stress tests. Am J Cardiol 43:899-906, 1979.Crossref 19. Ritchie JL, Trobaugh GB, Hamilton GW, et al: Myocardial imaging with thallium-201 at rest and during exercise: Comparison with coronary arteriography and resting and stress electrocardiography. Circulation 56:66-71, 1977.Crossref 20. Carrillo AP, Marks DS, Pickard SD, et al: Correlation of exercise 201thallium myocardial scan with coronary arteriograms and the maximal exercise test. Chest 73:321-326, 1978.Crossref 21. Verani MS, Marcus ML, Razzak MA, et al: Sensitivity and specificity of thallium-201 perfusion scintigrams under exercise in diagnosis of coronary artery disease. J Nucl Med 19:773-782, 1978. 22. Bailey IK, Griffith LSC, Rouleau J, et al: Thallium-201 myocardial perfusion imaging at rest and during exercise: Comparative sensitivity to electrocardiography in coronary artery disease. Circulation 55:79-87, 1977.Crossref 23. Iskandrian AS, Mintz GS, Croll MN, et al: Exercise thallium-201 myocardial scintigraphy: Advantages and limitations. Cardiology , to be published. 24. Gaffney FA, Wohl AJ, Blomquist CG, et al: Thallium-201 myocardial perfusion studies in patients with the mitral valve prolapse syndrome. Am J Med 64:21-26, 1978.Crossref 25. Bailey IK, Come PC, Kelley DT, et al: Thallium-201 myocardial perfusion imaging in aortic valve stenosis. Am J Cardiol 40:889-898, 1977.Crossref 26. Massie BM, Botvinick EH, Brundage BH, et al: Relationship of regional myocardial perfusion to segmental wall motion: A physiologic basis for understanding the presence and reversibility of asynergy. Circulation 58:1154-1162, 1978.Crossref 27. Greenberg BH, Hart R, Botvinick EH, et al: Thallium-201 myocardial perfusion scintigraphy to evaluate patients after coronary bypass surgery. Am J Cardiol 42:167-176, 1978.Crossref 28. Albro PC, Gould KL, Westcott RJ, et al: Noninvasive assessment of coronary stenosis by myocardial imaging during pharmacologic coronary vasodilatation: III. Clinical trials. Am J Cardiol 42:751-760, 1978.Crossref 29. Vogel RA, Kirch DL, Lee Free MT, et al: Thallium-201 myocardial perfusion scintigraphy: Results of standard and multi-pinhole tomographic technique. Am J Cardiol 43:787-791, 1979.Crossref 30. Iskandrian AS, Scherer H, Croll MN, et al: Exercise thallium-201 myocardial scans in patients with disease limited to the secondary branches of the left coronary system. Clin Cardiol 2:121-125, 1979.Crossref

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Mar 1, 1980

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