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Retinitis: A Manifestation of Primary or Secondary Cytomegalovirus Infection?-Reply

Retinitis: A Manifestation of Primary or Secondary Cytomegalovirus Infection?-Reply This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract In Reply.— Dr Murray's comments regarding CMV retinitis are timely and interesting. I agree with him that only a prospective serological study can determine whether CMV retinitis represents a primary or secondary infection. CMV retinitis is not a very common affliction, although it probably has not been adequately sought for. I do not have any preconceived ideas as to its pathogenesis. Cytomegalovirus retinitis may result from widespread viral dissemination during primary or secondary infection, or the retinitis may represent reactivation of a CMV infection in situ. Possibly, the virus is deposited during an early or even congenital infection and is activated when the patient is immunosuppressed. The retina may be a relatively uncommon, although well-known, site of primary infection, and this may account for the infrequency of CMV retinitis.Finally, I do not want our article to leave the impression that the triad of fever, leukopenia, and atypical lymphocytosis is http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

Retinitis: A Manifestation of Primary or Secondary Cytomegalovirus Infection?-Reply

Archives of Internal Medicine , Volume 138 (1) – Jan 1, 1978

Retinitis: A Manifestation of Primary or Secondary Cytomegalovirus Infection?-Reply

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract In Reply.— Dr Murray's comments regarding CMV retinitis are timely and interesting. I agree with him that only a prospective serological study can determine whether CMV retinitis represents a primary or secondary infection. CMV retinitis is not a very common affliction, although it probably has not been adequately sought for. I do not have...
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References (1)

Publisher
American Medical Association
Copyright
Copyright © 1978 American Medical Association. All Rights Reserved.
ISSN
0003-9926
eISSN
1538-3679
DOI
10.1001/archinte.1978.03630250109033
Publisher site
See Article on Publisher Site

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract In Reply.— Dr Murray's comments regarding CMV retinitis are timely and interesting. I agree with him that only a prospective serological study can determine whether CMV retinitis represents a primary or secondary infection. CMV retinitis is not a very common affliction, although it probably has not been adequately sought for. I do not have any preconceived ideas as to its pathogenesis. Cytomegalovirus retinitis may result from widespread viral dissemination during primary or secondary infection, or the retinitis may represent reactivation of a CMV infection in situ. Possibly, the virus is deposited during an early or even congenital infection and is activated when the patient is immunosuppressed. The retina may be a relatively uncommon, although well-known, site of primary infection, and this may account for the infrequency of CMV retinitis.Finally, I do not want our article to leave the impression that the triad of fever, leukopenia, and atypical lymphocytosis is

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Jan 1, 1978

There are no references for this article.