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TPN Control Needed

TPN Control Needed Abstract Total parenteral nutrition (TPN) has been increasingly used since 1968. It is now an established method of maintaining normal nitrogen balance in patients who otherwise would be unable to do so. The use of all forms of intravenous infusion therapy has been largely responsible for the success in treating critically ill patients. In this issue of the Archives (p 1686), Plouffe et al discuss an outbreak of infection caused by contamination of the system used in preparing infusion fluid. Although Candida albicans is the most common cause of fungemia complicating intravenous therapy, other species such as C parapsilosis have been isolated, and the clinical picture appears to be the same, regardless of which Candida species is responsible.1 Patients receiving hyperalimentation who develop candidemia usually clear the fungus from the blood shortly after the infusion catheter has been removed. Phagocytosis and the clumping factor in normal human serum destroys small References 1. Young RC, Bennett JE, Geelhood GW, et al: Fungemia with compromised host resistance . Ann Intern Med 80:605-612, 1974.Crossref 2. Louria DB, Smith JK, Brayton RG, et al: Anti-Candida factors in serum and their inhibitors . J Infect Dis 125:102-114, 1972.Crossref 3. Goldmann DA, Maki DG: Infection control in total parenteral nutrition . JAMA 223:1360-1364, 1973.Crossref 4. Recommended methods for compounding intravenous admixtures in hospitals, National Coordinating Committee on Large Volume Parenterals . Am J Hosp Pharm 32:261-270, 1975. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

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References (6)

Publisher
American Medical Association
Copyright
Copyright © 1977 American Medical Association. All Rights Reserved.
ISSN
0003-9926
eISSN
1538-3679
DOI
10.1001/archinte.1977.03630240007005
Publisher site
See Article on Publisher Site

Abstract

Abstract Total parenteral nutrition (TPN) has been increasingly used since 1968. It is now an established method of maintaining normal nitrogen balance in patients who otherwise would be unable to do so. The use of all forms of intravenous infusion therapy has been largely responsible for the success in treating critically ill patients. In this issue of the Archives (p 1686), Plouffe et al discuss an outbreak of infection caused by contamination of the system used in preparing infusion fluid. Although Candida albicans is the most common cause of fungemia complicating intravenous therapy, other species such as C parapsilosis have been isolated, and the clinical picture appears to be the same, regardless of which Candida species is responsible.1 Patients receiving hyperalimentation who develop candidemia usually clear the fungus from the blood shortly after the infusion catheter has been removed. Phagocytosis and the clumping factor in normal human serum destroys small References 1. Young RC, Bennett JE, Geelhood GW, et al: Fungemia with compromised host resistance . Ann Intern Med 80:605-612, 1974.Crossref 2. Louria DB, Smith JK, Brayton RG, et al: Anti-Candida factors in serum and their inhibitors . J Infect Dis 125:102-114, 1972.Crossref 3. Goldmann DA, Maki DG: Infection control in total parenteral nutrition . JAMA 223:1360-1364, 1973.Crossref 4. Recommended methods for compounding intravenous admixtures in hospitals, National Coordinating Committee on Large Volume Parenterals . Am J Hosp Pharm 32:261-270, 1975.

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Dec 1, 1977

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