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R. Rieselbach, S. Shankel, E. Slatopolsky, H. Lubowitz, N. Bricker (1967)
Glucose titration studies in patients with chronic progressive renal disease.The Journal of clinical investigation, 46 2
A. Walker, C. Hudson (1936)
THE REABSORPTION OF GLUCOSE FROM THE RENAL TUBULE IN AMPHIBIA AND THE ACTION OF PHLORHIZIN UPON ITAmerican Journal of Physiology, 118
Royer P Debre R (1956)
Les insuffisances congenitales du tubule renal chez l'enfant.Sem Hop Paris, 32
Wadi Sue, Manuel Martinez-Maldonado, Diane Rouse, Arthur Termy (1969)
Effect of expansion of extracellular fluid volume on renal phosphate handling.The Journal of clinical investigation, 48 10
Boylan JW Deetjen P (1966)
Factors influencing glucose reabsorption in single perfused rat nephron, abstracted.Fed Proc, 25
S. Massry, J. Coburn, C. Kleeman (1969)
The influence of extracellular volume expansion on renal phosphate reabsorption in the dog.The Journal of clinical investigation, 48 7
D. Thompson, M. Barrett (1953)
Urine flow and solute excretion during osmotic diuresis.The American journal of physiology, 176 1
M. Purkerson, H. Lubowitz, R. White, N. Bricker (1969)
On the influence of extracellular fluid volume expansion on bicarbonate reabsorption in the rat.The Journal of clinical investigation, 48 9
F. Chinard, W. Taylor, M. Nolan, T. Enns (1957)
Transport of glucose by the renal tubule cells of anesthetized dogs.Science, 125 3251
N. Kurtzman, M. White, P. Rogers, J. Flynn (1972)
Relationship of sodium reabsorption and glomerular filtration rate to renal glucose reabsorption.The Journal of clinical investigation, 51 1
N. Kurtzman (1970)
Regulation of renal bicarbonate reabsorption by extracellular volume.The Journal of clinical investigation, 49 3
A. Robson, P. Srivastava, N. Bricker (1968)
The influence of saline loading on renal glucose reabsorption in the rat.The Journal of clinical investigation, 47 2
J. Fine (1965)
Glucose Content of Normal UrineBritish Medical Journal, 1
D. Thompson, M. Barrett, R. Pitts (1951)
Significance of glomerular perfusion in relation to variability of filtration rate.The American journal of physiology, 167 2
J. Shannon (1939)
RENAL TUBULAR EXCRETIONPhysical Review, 19
Maack T Bowman RH (1971)
The effect of sodium load on glucose transport in the isolated perfused rat kidney, abstracted.Fed Proc, 30
J. Mcphaul, J. Simonaitis (1968)
Observations on the mechanisms of glucosuria during glucose loads in normal and nondiabetic subjects.The Journal of clinical investigation, 47 4
G. Monasterio, J. Oliver, G. Muiesan, G. Pardelli, V. Marinozzi, M. Macdowell (1964)
RENAL DIABETES AS A CONGENITAL TUBULAR DYSPLASIA.The American journal of medicine, 37
M. Levy, J. Ankeney (1952)
Influence of Glomerular Filtration Rate upon the Renal Tubular Reabsorption of Sodium.∗ †Proceedings of the Society for Experimental Biology and Medicine, 79
S. Shankel, A. Robson, N. Bricker (1967)
On the mechanism of the splay in the glucose titration curve in advanced experimental renal disease in the rat.The Journal of clinical investigation, 46 2
P. Christensen (1958)
Tubular reabsorption of glucose during pregnancy.Scandinavian journal of clinical and laboratory investigation, 10 4
T. Csáky, K. Prachuabmoh, B. Eiseman, P. Ho (1965)
The effect of digitalis on the renal tubular transport of glucose in normal and in heartless dogs.The Journal of pharmacology and experimental therapeutics, 150 2
A. Walker, P. Bott, J. Oliver, M. Macdowell (1941)
THE COLLECTION AND ANALYSIS OF FLUID FROM SINGLE NEPHRONS OF THE MAMMALIAN KIDNEYAmerican Journal of Physiology, 134
E. Slatopolsky, P. Hoffsten, M. Purkerson, N. Bricker (1970)
On the influence of extracellular fluid volume expansion and of uremia on bicarbonate reabsorption in man.The Journal of clinical investigation, 49 5
R. Bowman, T. Maack (1972)
Glucose transport by the isolated perfused rat kidney.The American journal of physiology, 222 6
F. Chinard, W. Taylor, M. Nolan, T. Enns (1959)
Renal handling of glucose in dogs.The American journal of physiology, 196 3
Epstein JM Robson AM (1972)
The influence of an osmotic diuresis on renal glucose transport, abstracted.Proc Int Congress Nephrol, 5
Abstract Glucose reabsorption has been recently shown to be linked to that of sodium. When sodium reabsorption is enhanced, so is glucose reabsorption; when sodium reabsorption is depressed, so is that of glucose. Glucose reabsorption, like that of sodium, is also tied to the glomerular filtration rate (GFR), increasing when the GFR increases and falling when the GFR falls (glomerular tubular balance). Thus, no maximal rate of tubular reabsorption exists for glucose, at least in the classical sense. Those altered states of homeostasis accompanied by hyperglycemia and volume contraction (the major stimulus to increased renal reabsorption of sodium) will also be accompanied by increased glucose reabsorption that will both accentuate and perpetuate the hyperglycemia. References 1. Fine J: Glucose content of normal urine. Br Med J 1:1209-1214, 1965.Crossref 2. Chinard FP, et al: Renal handling of glucose in dogs. Am J Physiol 196:535-544, 1959. 3. Walker AM, et al: The collection and analysis of fluid from single nephrons of the mammalian kidney. Am J Physiol 118:130-143, 1937. 4. Walker AM, Hudson CL: The reabsorption of glucose from the renal tubule of amphibia and the action of phlorizin upon it. Am J Physiol 118:130-143, 1937. 5. Chinard FP, et al: Transport of glucose by the renal tubule cells of anesthetized dogs. Science 125:736-737, 1957.Crossref 6. Shannon JA: Renal tubular excretion. Physiol Rev 19:63-93, 1939. 7. Deetjen P, Boylan JW: Factors influencing glucose reabsorption in single perfused rat nephron, abstracted. Fed Proc 25:392, 1966. 8. Thompson DD, Barrett MJ, Pitts RF: Significance of glomerular perfusion in relation to variability of filtration rate. Am J Physiol 167:546-552, 1951. 9. Kurtzman NA: Regulation of renal bicarbonate reabsorption by extracellular volume. J Clin Invest 49:586-595, 1970.Crossref 10. Slatopolsky E, et al: On the influence of extracellular fluid volume expansion and of uremia on bicarbonate reabsorption in man. J Clin Invest 49:988-998, 1970.Crossref 11. Purkerson ML, et al: On the influence of extracellular fluid volume expansion on bicarbonate reabsorption in the rat. J Clin Invest 48:1754-1760, 1969.Crossref 12. Suki WN, et al: Effect of expansion of extracellular fluid volume on renal phosphate handling. J Clin Invest 48:1888-1894, 1969.Crossref 13. Massry SG, Coburn JW, Kleeman CR: The influence of extracellular volume expansion on renal phosphate reabsorption in the dog. J Clin Invest 48:1237-1245,1969.Crossref 14. Robson AM, Shrivastava PL, Bricker NS: The influence of saline loading on renal glucose reabsorption in the rats. J Clin Invest 47:329-335, 1968.Crossref 15. Kurtzman NA, et al: Relationship of sodium reabsorption and glomerular filtration rate to renal glucose reabsorption. J Clin Invest 51:127-133, 1972.Crossref 16. Shankel SW, Robson AM, Bricker NS: On the mechanism of the splay in the glucose titration curve in advanced experimental renal disease in the rat. J Clin Invest 46:164-172, 1967.Crossref 17. Rieselbach RE, et al: Glucose titration studies in patients with chronic progressive renal disease. J Clin Invest 46:157-163, 1967.Crossref 18. Csaky TZ, et al: The effect of digitalis on the renal tubular transport of glucose in normal and heartless dogs. J Pharmacol Exp Ther 150:275-278, 1965. 19. Bowman RH, Maack T: The effect of sodium load on glucose transport in the isolated perfused rat kidney, abstracted. Fed Proc 30:608, 1971. 20. Bowman RH, Maack T: Glucose transport by the isolated perfused rat kidney. Am J Physiol 222:1499-1504, 1972. 21. Levy MH, Ankerey JL: Influence of glomerular filtration rate upon the renal tubular reabsorption of sodium. Proc Soc Exp Biol Med 79:491-494, 1952.Crossref 22. Thompson DD, Barrett MJ: Urine flow and solute excretion during osomotic diuresis. Am J Physiol 176:33-38, 1954. 23. Robson AM, Epstein JM, Bricker NS: The influence of an osmotic diuresis on renal glucose transport, abstracted. Proc Int Congress Nephrol 5:132, 1972. 24. McPhaul JJ Jr, Simonaitis JJ: Observations on the mechanisms of glycosuria during glucose loads in normal and non-diabetic subjects. J Clin Invest 47:702-711, 1968.Crossref 25. Debre R, Royer P, Lestradet H: Les insuffisances congenitales du tubule renal chez l'enfant. Sem Hop Paris 32:235-254, 1956. 26. Monasterio G, et al: Renal diabetes as a congenital tubular dysplasia. Am J Med 37:44-61, 1964.Crossref 27. Christensen PJ: Tubular reabsorption of glucose during pregnancy. Scand J Clin Lab Invest 10:364-371, 1958.Crossref
Archives of Internal Medicine – American Medical Association
Published: Jun 1, 1973
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