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R. Olsson, J. Kirby, M. Romansky (1961)
Pneumococcal meningitis in the adult. Clinical, therapeutic, and prognostic aspects in forty-three patients.Annals of internal medicine, 55
M. Finland, John Brown, Albert Rauh (1938)
Treatment of Pneumococcic MeningitisThe New England Journal of Medicine, 218
J. Alexander, H. Flippin, G. Eisenberg (1953)
Pneumococcic meningitis; study of one hundred two cases.A.M.A. archives of internal medicine, 91 4
J.D. Alexander , H.F. Flippin, G.M. and Eisenberg (1953)
Pneumococcic MeningitisArch Intern Med, 91
(1962)
"Significance Limits for the Four-Fold Table Test," Documenta Geigy Scientific Tables
M.N. Swartz (1965)
Bacterial Meningitis: A Review of Selected AspectsN Eng J Med, 272
R.J. Haggerty (1964)
Acute Bacterial MeningitisAdvances Pediat, 13
M.H. Lepper (1959)
Treatment of Pneumococcic MeningitisArch Intern Med, 104
R. Austrian (1964)
THE ROLE OF TOXEMIA AND OF NEURAL INJURY IN THE OUTCOME OF PNEUMOCOCCAL MENINGITISThe American Journal of the Medical Sciences, 247
Abstract DESPITE the availability of an effective therapy, the prognosis of pneumococcal meningitis has been quite variable from one institution to another, even in recent years. Lepper and Spies 1 reported a 10% case fatality rate for 68 patients. Olsson et al2 recorded 65% deaths in 43 cases. Swartz and Dodge 3 had 29% mortality for 56 cases. Since the therapeutic regimens in these hospitals were similar, the differences in outcome must have been due to differences in case material. For example, age is an important characteristic in relation to results. The series with the lowest fatality rate 1 had a large proportion of young patients while the series with the highest mortality rate 2 had many old patients. Barring changes in admission policy, trends in prognosis for a given disease at a single institution over a period of time are likely to reflect the influence of changes in therapy References 1. Lepper, M.H., and Spies, H.W.: Treatment of Pneumococcic Meningitis , Arch Intern Med 104: 253-259 ( (Aug) ) 1959.Crossref 2. Olsson, R.A.; Kirby, J.C.; and Romansky, M.J.: Pneumococcal Meningitis in the Adult: Clinical, Therapeutic and Prognostic Aspects in Forty-three Patients , Ann Intern Med 55:545-549 ( (Oct) ) 1961.Crossref 3. Swartz, M.N., and Dodge, P.R.: Bacterial Meningitis: A Review of Selected Aspects , N Eng J Med 272:725-731, 779-787, 842-848, 898-902, 954-960, 1003-1010 and ( (April 8) , 15, 22, 29; May 6, 13) 1965.Crossref 4. Alexander, J.D., Jr.; Flippin, H.F.; and Eisenberg, G.M.: Pneumococcic Meningitis; Study of One Hundred Two Cases , Arch Intern Med 91:440-447 ( (April) ) 1953.Crossref 5. "Significance Limits for the Four-Fold Table Test," Documenta Geigy Scientific Tables , ed 6, Ardsley, NY: Geigy Pharmaceuticals, 1962, pp 109-123. 6. Haggerty, R.J., and Ziai, M.: Acute Bacterial Meningitis , Advances Pediat 13:129-181, 1964. 7. Austrian, R.: The Role of Toxemia and of Neural Injury in the Outcome of Pneumococcal Meningitis , Amer J Med Sci 247:257-262 ( (March) ) 964.Crossref
Archives of Internal Medicine – American Medical Association
Published: Nov 1, 1967
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