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C. Best, N. Taylor (1955)
The physiological basis of medical practice : a text in applied physiology
R. Scott (1920)
OBSERVATIONS ON THE PATHOLOGIC PHYSIOLOGY OF CHRONIC PULMONARY EMPHYSEMAJAMA Internal Medicine, 26
J. S. Haldane (1905)
Regulation of the Lung-VentilationJ. Physiol., 32
R. W. Scott (1920)
Observations on the Pathologic Physiology of Chronic Pulmonary EmphysemaArch. Int. Med., 26
Prime Fj, Westlake Ek (1954)
The respiratory response to CO2 in emphysema.Clinical Science, 13
J. Holman, G. Shires (1949)
Quantitative studies on ventilation during inhalation of carbon dioxide in normal and emphysematous patients.American heart journal, 37 7
S. Tenney (1954)
Ventilatory response to carbon dioxide in pulmonary emphysema.Journal of applied physiology, 6 8
J. H. Comroe (1950)
Methods in Medical Research, 2
Donald Kw, Christie Rv (1949)
The respiratory response to carbon dioxide and anoxia in emphysema.Clinical Science, 8
Abstract Chronic pulmonary disease, particularly emphysema, presents a problem in a hospital treating males of the older age group. Pulmonary emphysema may be encountered as a complication of any disease, but in spite of its high incidence, little is known concerning its basic abnormal physiology. The importance of carbon dioxide in the control of respiration was first considered by Miescher-Rush, cited by Best and Taylor,1 in 1885, and amplified by Haldane and Priestley,2 who pointed out the importance of the blood pCO2 as one of the controlling factors. Scott3 related the ventilatory response of his subjects to the inhalation of CO2 in varying concentrations in view of the emphysematous patient's increased tolerance to a high alveolar CO2 concentration. He concluded that the diminished response in the emphysematous persons as compared with the normal was due to the increased buffering capacity of the body fluids. Donald and Christie4 expanded Scott's work References 1. Best, C. H., and Taylor, N. B.: Physiological Basis of Medical Practice: A Text in Applied Physiology , Ed. 6, Baltimore, Williams & Wilkins Company, 1955, p. 408. 2. Haldane, J. S., and Priestly, J. G.: Regulation of the Lung-Ventilation , J. Physiol. 32: 224, 1905. 3. Scott, R. W.: Observations on the Pathologic Physiology of Chronic Pulmonary Emphysema , Arch. Int. Med. 26:544, 1920.Crossref 4. Donald, K. W., and Christie, R. V.: The Respiratory Response to Carbon Dioxide and Anoxia in Emphysema , Clin. Sc. 8:33, 1949. 5. Comroe, J. H., Jr., Editor: Methods in Medical Research , Chicago, The Year Book Publishers, Inc., 1950, Vol. 2, p. 212. 6. Prime, F. J., and Westlake, E. K.: The Respiratory Response to CO2 in Emphysema , Clin. Sc. 13:321, 1954. 7. Best, C. H., and Taylor, N. B.,1 p. 431. 8. Tenney, S. M.: Ventilatory Response to Carbon Dioxide in Pulmonary Emphysema , J. Appl. Physiol. 6:477, 1954. 9. Holman, J., and Shires, G. T.: Quantitative Studies of Ventilation During Inhalation of Carbon Dioxide in Normal and Emphysematous Patients , Am. Heart J. 37:1101, 1949.Crossref
A.M.A. Archives of Internal Medicine – American Medical Association
Published: Mar 1, 1957
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