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Milton Cohen (1938)
Vitamin C deficiency: Sensitivity to neoarsphenamine and anaphylactic shockJournal of Allergy, 10
F. Cormia (1937)
Experimental Arsphenamine Dermatitis: the Influence of Vitamin C in the Production of Arsphenamine Sensitiveness.Canadian Medical Association journal, 36 4
G. Walther (1938)
Failures with vitamin C therapy.Medizinische Klinik, 34
D. K. Miller (1938)
Ascorbic Acid in the Treatment of Thrombocytopenic PurpuraJ. Clin. Investigation, 15
F. E. Cormia (1937)
Experimental Arsphenamine Dermatitis: The Influence of Vitamin C in the Production of Arsphenamine SensitivenessCanad. M. A. J., 36
G. Dalldorf (1933)
A Sensitive Test for Subclinical Scurvy in ManAm. J. Dis. Child., 46
A. Böger (1934)
Ueber die Stillung schwerster Blutungen bei allen Foramen der h�morrhogischen Diathese und der Hemophilie durch parenterale Zufuhr von C-vitamin (Cebion Merck)München. med. Wchnschr., 81
G. Dalldorf (1933)
A SENSITIVE TEST FOR SUBCLINICAL SCURVY IN MANJAMA Pediatrics, 46
B. Streitmann (1937)
Biologische Pruefungen von Arsenobenzolderivaten: II. Vergleichende Untersuchungen ueber die Sensibilisierungsfaehigkeit einzelner ArsenobenzolderivateArch. f. Dermat. u. Syph., 175
G. Walther (1938)
Misserfolge bei Vitamin C TherapieMed. Klin., 34
M. Sulzberger, B. Oser (1935)
Influence of Ascorbic Acid of Diet on Sensitization of Guinea Pigs to NeoarsphenamineProceedings of the Society for Experimental Biology and Medicine, 32
E. Osgood, H. Haskins (1923)
A New Permanent Standard for Estimation of Hemoglobin by the Acid Hematin MethodJournal of Biological Chemistry, 57
C. Chapman, C. Morrell (1935)
Influence of Vitamin C on Development of Skin Sensitivity to Neoarsphenamine in the Guinea PigProceedings of the Society for Experimental Biology and Medicine, 32
A. Böger (1935)
Vitamin C und BlutMünchen. med. Wchnschr., 82
I. Dainow (1937)
Intol�rance aux ars�nob�nzenes et vitamin CPresse méd., 45
P. Giroud (1936)
Influence du r�gime alimentaire sur la sensibilit� du lapin � la s�ro-anaphylaxieCompt. rend. Soc. de biol., 122
F. Cormia (1938)
Experimental Arsphenamine Sensitization: Further Observations on the Reactions to Arsphenamine in Guinea Pigs Given Staphylococcus Toxin, and in Guinea Pigs with Induced Streptococcal Infection1Journal of Investigative Dermatology, 1
I. S. Wright (1936)
Pharmacologic and Therapeutic Properties of Crystalline Vitamin C (Cevitamic Acid) with Especial Reference to Its Effect on Capillary FragilityArch. Int. Med., 57
I. Wright, A. Lilienfeld (1936)
Pharmacologic and therapeutic properties of crystalline vitamin C (cevitamic acid) with especial reference to its effects on the capillary fragility.JAMA Internal Medicine, 57
H. Rees, E. Ecker (1923)
AN IMPROVED METHOD FOR COUNTING BLOOD PLATELETSJAMA, 80
E. H. Falconer , N. N. Epstein (1936)
Purpura Haemorrhagica Following the Administration of Neoarsphenamine: Reaction to Neoarsphenamine Compared with Reaction to MapharsenArch. Int. Med., 58
E. Vogt (1935)
Ueber die Behandlung gyn�kologischer Blutungen mit Vitamin CMünchen. med. Wchnschr., 82
L. S. P. Davidson , C. Davenport (1937)
Discussion on Purpuric Conditions in Man and AnimalsProc. Roy. Soc. Med., 30
D. G. Friend (1938)
Arsphenamine Sensitivity and Vitamin CAm. J. Syph., Gonor. & Ven. Dis., 22
J. Vaughan (1937)
Treatment of Thrombocytopenic Purpura*British Medical Journal, 2
E. Falconer, N. Epstein, G. Wever (1936)
PURPURA HAEMORRHAGICA FOLLOWING THE ADMINISTRATION OF NEOARSPHENAMINE: THE REACTION TO NEOARSPHENAMINE COMPARED WITH THE REACTION TO MAPHARSENJAMA Internal Medicine, 58
H. Winckelmann (1938)
Zur Vitamin C Behandlung von h�morrhagischen DiathesenMed. Klin., 34
Abstract Since 1933 we have had an opportunity to study 7 patients showing reactions accompanied by thrombopenic purpura following arsphenamine therapy. These patients have submitted to further injections of arsphenamine preparations; thereby we have been allowed to reproduce experimentally their attacks of purpura. An opportunity has thus been afforded for study of the effects of oral and parenteral administration of vitamin C on this type of sensitivity. Our interest in the effect of vitamin C on purpura due to administration of neoarsphenamine was stimulated by reports in the literature that tended to show a relationship between vitamin C deficiency and arsphenamine sensitivity and also by reports of the clinical use of vitamin C as an agent to ameliorate the toxic effects of the arsphenamines. We have been interested also in several reports concerning the therapeutic value of ascorbic acid in the treatment of patients having idiopathic thrombopenic purpura. In 1935 Sulzberger References 1. Sulzberger, M. B., and Oser, B. L.: Influence of Ascorbic Acid of Diet on Sensitization of Guinea Pigs to Neoarsphenamine , Proc. Soc. Exper. Biol. & Med. 32:716, 1935. 2. Streitmann, B., and Wiedmann, A.: Biologische Pruefungen von Arsenobenzolderivaten: II. Vergleichende Untersuchungen ueber die Sensibilisierungsfaehigkeit einzelner Arsenobenzolderivate , Arch. f. Dermat. u. Syph. 175:696, 1937. 3. Cormia, F. E.: Experimental Arsphenamine Dermatitis: The Influence of Vitamin C in the Production of Arsphenamine Sensitiveness , Canad. M. A. J. 36:392, 1937. 4. Cormia, F. E.: Experimental Arsphenamine Sensitization: Further Observations on the Reactions to Arsphenamine in Guinea Pigs Given Staphylococcus Toxin, and in Guinea Pigs with Induced Streptococcal Infection , J. Invest. Dermat. 1:199, 1938. 5. Chapman, C. W., and Morrell, C. A.: Influence of Vitamin C on Development of Skin Sensitivity to Neoarsphenamine in the Guinea Pig , Proc. Soc. Exper. Biol. & Med. 32:813, 1935. 6. Cohen, M. B.: Vitamin C Deficiency: Sensitivity to Neoarsphenamine and Anaphylactic Shock , J. Allergy 10:15, 1938. 7. Friend, D. G., and Marquis, H. H.: Arsphenamine Sensitivity and Vitamin C , Am. J. Syph., Gonor. & Ven. Dis. 22:239, 1938. 8. Dainow, I.: Intolérance aux arsénobènzenes et vitamin C , Presse méd. 45: 1670, 1937. 9. Böger, A., and Schröder, H.: Ueber die Stillung schwerster Blutungen bei allen Foramen der hämorrhogischen Diathese und der Hemophilie durch parenterale Zufuhr von C-vitamin (Cebion Merck) , München. med. Wchnschr. 81: 1335, 1934. 10. Winckelmann, H.: Zur Vitamin C Behandlung von hämorrhagischen Diathesen , Med. Klin. 34:906, 1938. 11. Vogt, E.: Ueber die Behandlung gynäkologischer Blutungen mit Vitamin C , München. med. Wchnschr. 82:263, 1935. 12. Miller, D. K., and Rhoads, C. P.: Ascorbic Acid in the Treatment of Thrombocytopenic Purpura , J. Clin. Investigation 15:462, 1938. 13. Böger, A., and Morton, W.: Vitamin C und Blut , München. med. Wchnschr. 82:899, 1935. 14. Walther, G.: Misserfolge bei Vitamin C Therapie , Med. Klin. 34:260, 1938. 15. Vaughan, J. M.: Treatment of Thrombocytopenic Purpura , Brit. M. J. 2: 842, 1937. 16. Davidson, L. S. P.; Davenport, C., and Rabagliati, D. S.: Discussion on Purpuric Conditions in Man and Animals , Proc. Roy. Soc. Med. 30:715, 1937. 17. Wright, I. S., and Lilienfeld, A.: Pharmacologic and Therapeutic Properties of Crystalline Vitamin C (Cevitamic Acid) with Especial Reference to Its Effect on Capillary Fragility , Arch. Int. Med. 57:241 ( (Feb.) ) 1936. 18. Osgood, E. E., and Haskins, H. D.: A New Permanent Standard for Estimation of Hemoglobin by the Acid Hematin Method , J. Biol. Chem. 57:107, 1923. 19. Rees, H. M., and Ecker, E. E.: An Improved Method for Counting Blood Platelets , J. A. M. A. 80:621 ( (March 3) ) 1923. 20. Dalldorf, G.: A Sensitive Test for Subclinical Scurvy in Man , Am. J. Dis. Child. 46:794 ( (Oct.) ) 1933. 21. Falconer, E. H.; Epstein, N. N., and Wever, G. K.: Purpura Haemorrhagica Following the Administration of Neoarsphenamine: Reaction to Neoarsphenamine Compared with Reaction to Mapharsen , Arch. Int. Med. 58:495 ( (Sept.) ) 1936.Crossref 22. Giroud, P., and Giroud, A.: Influence du régime alimentaire sur la sensibilité du lapin à la séro-anaphylaxie , Compt. rend. Soc. de biol. 122:537, 1936.
Archives of Internal Medicine – American Medical Association
Published: Aug 1, 1940
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