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DIABETIC COMA

DIABETIC COMA Abstract The conquest of diabetic coma is in sight. During 1929 and 1930 in Stettin, Germany, with a population of 270,000, there was not a single death from diabetic coma.1 Boston cannot make so good a showing, but the following letter from the health commissioner of the city speaks for itself: March 31, 1936. My dear Dr. Joslin: I am happy to report to you that in the City of Boston during 1935 there was not a death from any cause whatsoever in a diabetic under nineteen years of age. During this twelve month period there were in all 288 deaths classified as diabetes and I understand including those with diabetes as a secondary cause 301 deaths. Yours very truly, (Signed) William B. Keeler, M.D. Health Commissioner In this twelfth paper on diabetic coma we shall (1) present 42 new cases, bringing to 318 the total number of patients treated References 1. Gottschalk, A.: Das Stettiner System der Diabetikernachsorge , Klin. Wchnschr. 10:704 ( (April 11) ) 1931.Crossref 2. Hartmann, A. F.: Treatment of Severe Diabetic Acidosis , Arch. Int. Med. 56:413 ( (Sept.) ) 1935.Crossref 3. footnote 1a 4. Marble, A.; Root, H. F., and White, P.: Diabetic Coma , New England J. Med. 212:288 ( (Feb. 14) ) 1935.Crossref 5. One case was not included, although the carbon dioxide-combining power was 19 volumes per cent, because the urine was sugar-free, owing to treatment in another hospital before transfer to us. 6. White, P., in Joslin, Elliott P.: The Treatment of Diabetes Mellitus , ed. 5, Philadelphia, Lea & Febiger, 1935, p. 509. 7. Joslin, E. P.: Diabetes: The Results of Past Treatment and Future Problems , Bull. Johns Hopkins Hosp. 29:82 ( (April) ) 1918. 8. Dillon, E. S., and Dyer, W. W.: Diabetic Coma with Extreme Hyperglycemia , Am. J. M. Sc. 190:683 ( (Nov.) ) 1935.Crossref 9. Hartmann,2 p. 418, table 3 10. p. 414, footnote. 11. Thorning, W. B., Jr., and Root, H. F.: Diverticula of the Duodenum and Diabetes , Am. J. Digest. Dis. & Nutrition 2:17 ( (March) ) 1935. 12. Sharkey, T. P., and Root, H. F.: Infection of the Urinary Tract in Diabetes , J. A. M. A. 104:2231 ( (June 22) ) 1935. 13. Schohl and Janney, quoted by Clark, A.: Escherichia Coli Bacilluria Under Ketogenic Treatment , Proc. Staff Meet., Mayo Clin. 6:605 ( (Oct. 14) ) 1931. 14. Richardson, R.: Immunity in Diabetes: I. Influence of Diabetes on Development of Antibacterial Properties in Blood , J. Clin. Investigation 12:1143 ( (Nov.) ) 1933 15. II. Relative Importance of Nutritional State and of Blood Sugar Level in Influencing Development of the Agglutinin After Typhoid Vaccine , Richardson J. Clin. Investigation 14:389 ( (July) ) 1935. 16. Horster, H.: Beitrag zur Klärung der Ursache der verminderten Widerstandsfähigkeit des zuckerkranken Organismus gegen Infektion , Deutsches Arch. f. klin. Med. 176:502 ( (July 9) ) 1934. 17. Joslin, E. P.: Diabetic Metabolism with High and Low Diets , Washington, D. C., Carnegie Institution of Washington, 1923, pp. 158-160. 18. Another interpretation would be that there was sufficient alkali in the body and no necessity to utilize this mechanism. 19. Goodall, H. W., and Joslin, E. P.: The Clinical Value of the Estimation of Ammonia in Diabetes , Boston M. J. 158:646 ( (May) ) 1908. 20. Van Slyke and Cullen ( J. Biol. Chem. 30:289, 1917) 21. Hartmann,2 p. 429, footnote 8 22. Van Slyke and Cullen ( J. Biol. Chem. 30:344, 1917) 23. Peters and Van Slyke ( Quantitative Clinical Chemistry , Baltimore, Williams & Wilkins Company, 1932, vol. 2, p. 251). 24. Hartmann,2 p. 434. 25. Atkinson, H. V., and Lusk, G.: The Influence of Lactic Acid upon Metabolism , J. Biol. Chem. 40:79 ( (Nov.) ) 1919. 26. Lusk, G.: The Behavior of Various Intermediary Metabolites upon Heat Production , J. Biol. Chem. 49:453 ( (Dec.) ) 1921. 27. Hartmann,2 p. 431. 28. Hartmann,2 p. 430. 29. Hartmann,2 p. 422, chart 4. 30. Hartmann,2 p. 428. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

DIABETIC COMA

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Publisher
American Medical Association
Copyright
Copyright © 1937 American Medical Association. All Rights Reserved.
ISSN
0730-188X
DOI
10.1001/archinte.1937.00170180002001
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Abstract

Abstract The conquest of diabetic coma is in sight. During 1929 and 1930 in Stettin, Germany, with a population of 270,000, there was not a single death from diabetic coma.1 Boston cannot make so good a showing, but the following letter from the health commissioner of the city speaks for itself: March 31, 1936. My dear Dr. Joslin: I am happy to report to you that in the City of Boston during 1935 there was not a death from any cause whatsoever in a diabetic under nineteen years of age. During this twelve month period there were in all 288 deaths classified as diabetes and I understand including those with diabetes as a secondary cause 301 deaths. Yours very truly, (Signed) William B. Keeler, M.D. Health Commissioner In this twelfth paper on diabetic coma we shall (1) present 42 new cases, bringing to 318 the total number of patients treated References 1. Gottschalk, A.: Das Stettiner System der Diabetikernachsorge , Klin. Wchnschr. 10:704 ( (April 11) ) 1931.Crossref 2. Hartmann, A. F.: Treatment of Severe Diabetic Acidosis , Arch. Int. Med. 56:413 ( (Sept.) ) 1935.Crossref 3. footnote 1a 4. Marble, A.; Root, H. F., and White, P.: Diabetic Coma , New England J. Med. 212:288 ( (Feb. 14) ) 1935.Crossref 5. One case was not included, although the carbon dioxide-combining power was 19 volumes per cent, because the urine was sugar-free, owing to treatment in another hospital before transfer to us. 6. White, P., in Joslin, Elliott P.: The Treatment of Diabetes Mellitus , ed. 5, Philadelphia, Lea & Febiger, 1935, p. 509. 7. Joslin, E. P.: Diabetes: The Results of Past Treatment and Future Problems , Bull. Johns Hopkins Hosp. 29:82 ( (April) ) 1918. 8. Dillon, E. S., and Dyer, W. W.: Diabetic Coma with Extreme Hyperglycemia , Am. J. M. Sc. 190:683 ( (Nov.) ) 1935.Crossref 9. Hartmann,2 p. 418, table 3 10. p. 414, footnote. 11. Thorning, W. B., Jr., and Root, H. F.: Diverticula of the Duodenum and Diabetes , Am. J. Digest. Dis. & Nutrition 2:17 ( (March) ) 1935. 12. Sharkey, T. P., and Root, H. F.: Infection of the Urinary Tract in Diabetes , J. A. M. A. 104:2231 ( (June 22) ) 1935. 13. Schohl and Janney, quoted by Clark, A.: Escherichia Coli Bacilluria Under Ketogenic Treatment , Proc. Staff Meet., Mayo Clin. 6:605 ( (Oct. 14) ) 1931. 14. Richardson, R.: Immunity in Diabetes: I. Influence of Diabetes on Development of Antibacterial Properties in Blood , J. Clin. Investigation 12:1143 ( (Nov.) ) 1933 15. II. Relative Importance of Nutritional State and of Blood Sugar Level in Influencing Development of the Agglutinin After Typhoid Vaccine , Richardson J. Clin. Investigation 14:389 ( (July) ) 1935. 16. Horster, H.: Beitrag zur Klärung der Ursache der verminderten Widerstandsfähigkeit des zuckerkranken Organismus gegen Infektion , Deutsches Arch. f. klin. Med. 176:502 ( (July 9) ) 1934. 17. Joslin, E. P.: Diabetic Metabolism with High and Low Diets , Washington, D. C., Carnegie Institution of Washington, 1923, pp. 158-160. 18. Another interpretation would be that there was sufficient alkali in the body and no necessity to utilize this mechanism. 19. Goodall, H. W., and Joslin, E. P.: The Clinical Value of the Estimation of Ammonia in Diabetes , Boston M. J. 158:646 ( (May) ) 1908. 20. Van Slyke and Cullen ( J. Biol. Chem. 30:289, 1917) 21. Hartmann,2 p. 429, footnote 8 22. Van Slyke and Cullen ( J. Biol. Chem. 30:344, 1917) 23. Peters and Van Slyke ( Quantitative Clinical Chemistry , Baltimore, Williams & Wilkins Company, 1932, vol. 2, p. 251). 24. Hartmann,2 p. 434. 25. Atkinson, H. V., and Lusk, G.: The Influence of Lactic Acid upon Metabolism , J. Biol. Chem. 40:79 ( (Nov.) ) 1919. 26. Lusk, G.: The Behavior of Various Intermediary Metabolites upon Heat Production , J. Biol. Chem. 49:453 ( (Dec.) ) 1921. 27. Hartmann,2 p. 431. 28. Hartmann,2 p. 430. 29. Hartmann,2 p. 422, chart 4. 30. Hartmann,2 p. 428.

Journal

Archives of Internal Medicine – American Medical Association

Published: Feb 1, 1937

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