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CHOLESTEROL OF THE BLOOD PLASMA IN HEPATIC AND BILIARY DISEASES

CHOLESTEROL OF THE BLOOD PLASMA IN HEPATIC AND BILIARY DISEASES Abstract As the liver is involved in a great many activities, it is not at all improbable that dissociated functional disturbances may arise when the organ is injured and that some functions are likely to suffer damage, whereas others remain intact or are only slightly affected. This may account for the invention of so many diverse liver function tests and the failure of any single one to satisfy the need for a uniformly accurate method of determining the functional capacity of the diseased liver. The studies have been directed toward the variations in the normal excretory and metabolic processes with which the liver is concerned. In addition, attempts have been made to evaluate the condition of the organ by increasing the burdens in tolerance tests with sugars, fats and proteins, as well as injection of pigments, exogenous substances such as dyes, cinchophen, etc. A discussion of the value of all these References 1. Rich, A. R.: Bull. Johns Hopkins Hosp. 47:338, 1930. 2. Greene, C. H.; Snell, A. M., and Walters, Waltman: Diseases of the Liver: I. A Survey of Tests for Hepatic Function , Arch. Int. Med. 36:248 ( (Aug.) ) 1925.Crossref 3. Schöndube, W.: Deutsche med. Wchnschr. 56:878 ( (May 23) )Crossref 4. 922 (May 30) 5. 965 (June 6) 1930. 6. Schrumpf, A.: Ztschr. f. klin. Med. 116:449, 1931. 7. Shay, H.; Schloss, E. M., and Rodis, I.: II. The Galactose Tolerance Test in the Differential Diagnosis of Jaundice , Arch. Int. Med. 47:650 ( (April) ) 1931.Crossref 8. Lichtman, S. S., and Sobotka, H.: J. Biol. Chem. 85:261, 1929. 9. Lichtman, S. S.: Cinchophen Oxidation Test of Function of Hepatic Cells , Arch. Int. Med. 48:98 ( (July) ) 1931.Crossref 10. Bernheim, A. R.: Proc. Soc. Exper. Biol. & Med. 25:675, 1928. 11. von Bergmann, G.: Klin. Wchnschr. 6:776, 1927. 12. Eilbott, W.: Ztschr. f. klin. Med. 106:529, 1927. 13. Harrop, G. A., Jr., and Barron, E. S. G.: J. Clin. Investigation 9:577, 1931. 14. Hueck, W.: Zentralbl. f. Path. u. path. Anat. 36:211, 1925. 15. Thannhauser, S. J.: Lehrbuch des Stoffwechsels und der Stoffwechselkrankheiten , Munich, J. F. Bergmann, 1929. 16. Gardner, J. A., and Gainsborough, H.: Quart. J. Med. 23:465, 1930. 17. Schönheimer, R.: Ztschr. f. physiol. Chem. 185:119, 1929. 18. Schönheimer, R.; von Behring, H.; Hummel, R., and Schindel, L.: Ztschr. f. physiol. Chem. 192:73, 1930. 19. Bürger, M.: Ergeb. d. inn. Med. u. Kinderh. 34:583, 1928. 20. Flint, A., Jr.: Am. J. M. Sc. 44:305, 1862. 21. Chauffard, A.; Laroche, G., and Grigaut, A.: Compt. rend. Soc. de biol. 73:23, 1912. 22. Beumer, H., and Bürger, M.: Ztschr. f. exper. Path. u. Therap. 13:343, 1913. 23. Feigl, J.: Biochem. Ztschr. 90:1, 1918. 24. Bang, I.: Biochem. Ztschr. 91:122, 1918. 25. Stepp, W.: Beitr. z. path. Anat. 69:233, 1921. 26. Rothschild, M. A., and Felsen, J.: The Cholesterol Content of the Blood in Various Hepatic Conditions , Arch. Int. Med. 24:520 ( (Nov.) ) 1919.Crossref 27. Chauffard, A.: La lithiase biliare , ed. 2, Paris, Masson et Cie, 1922. 28. Feigl, J.: Biochem. Ztschr. 86:1, 1918. 29. Thannhauser, S. J., and Schaber, H.: Klin. Wchnschr. 5:252, 1926.Crossref 30. Bürger, M., and Habs, H.: Klin. Wchnschr. 6:2221, 1927.Crossref 31. Stern, R., and Suchantke, G.: Arch. f. exper. Path. u. Pharmakol. 115:221, 1926.Crossref 32. Adler, A., and Lemmel, H.: Deutsches Arch. f. klin. Med. 158:173, 1928. 33. Epstein, E. Z.: The Cholesterol Partition of the Blood Plasma in Parenchymatous Diseases of the Liver , Arch. Int. Med. 47:82 ( (Jan.) ) 1931.Crossref 34. Gardner, J. A., and Gainsborough, H.: Biochem. J. 22:1048, 1928. 35. Bloor, W. R.: J. Biol. Chem. 24:227, 1916. 36. Bloor, W. R., and Knudson, A.: J. Biol. Chem. 27:107, 1916. 37. Eppinger, H.: Beitr. z. path. Anat. u. z. allg. Path. 31:230, 1902. 38. Barron, E. S. G., and Bumstead, J. H.: J. Exper. Med. 47:999, 1928.Crossref 39. Schönheimer, R., and von Behring, H.: Ztschr. f. physiol. Chem. 192:102, 1930. 40. Rothschild, M. A., and Wilensky, A. O.: M. Clin. North America 3:417, 1919. 41. Rothschild, M. A., and Rosenthal, N.: Am. J. M. Sc. 152:394, 1916.Crossref 42. Campbell, J. M. H.: Quart. J. Med. 18:123, 1924Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

CHOLESTEROL OF THE BLOOD PLASMA IN HEPATIC AND BILIARY DISEASES

EPSTEIN, EMANUEL Z.
Archives of Internal Medicine , Volume 50 (2) – Aug 1, 1932
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References (17)

Publisher
American Medical Association
Copyright
Copyright © 1932 American Medical Association. All Rights Reserved.
ISSN
0730-188X
DOI
10.1001/archinte.1932.00150150035004
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Abstract

Abstract As the liver is involved in a great many activities, it is not at all improbable that dissociated functional disturbances may arise when the organ is injured and that some functions are likely to suffer damage, whereas others remain intact or are only slightly affected. This may account for the invention of so many diverse liver function tests and the failure of any single one to satisfy the need for a uniformly accurate method of determining the functional capacity of the diseased liver. The studies have been directed toward the variations in the normal excretory and metabolic processes with which the liver is concerned. In addition, attempts have been made to evaluate the condition of the organ by increasing the burdens in tolerance tests with sugars, fats and proteins, as well as injection of pigments, exogenous substances such as dyes, cinchophen, etc. A discussion of the value of all these References 1. Rich, A. R.: Bull. Johns Hopkins Hosp. 47:338, 1930. 2. Greene, C. H.; Snell, A. M., and Walters, Waltman: Diseases of the Liver: I. A Survey of Tests for Hepatic Function , Arch. Int. Med. 36:248 ( (Aug.) ) 1925.Crossref 3. Schöndube, W.: Deutsche med. Wchnschr. 56:878 ( (May 23) )Crossref 4. 922 (May 30) 5. 965 (June 6) 1930. 6. Schrumpf, A.: Ztschr. f. klin. Med. 116:449, 1931. 7. Shay, H.; Schloss, E. M., and Rodis, I.: II. The Galactose Tolerance Test in the Differential Diagnosis of Jaundice , Arch. Int. Med. 47:650 ( (April) ) 1931.Crossref 8. Lichtman, S. S., and Sobotka, H.: J. Biol. Chem. 85:261, 1929. 9. Lichtman, S. S.: Cinchophen Oxidation Test of Function of Hepatic Cells , Arch. Int. Med. 48:98 ( (July) ) 1931.Crossref 10. Bernheim, A. R.: Proc. Soc. Exper. Biol. & Med. 25:675, 1928. 11. von Bergmann, G.: Klin. Wchnschr. 6:776, 1927. 12. Eilbott, W.: Ztschr. f. klin. Med. 106:529, 1927. 13. Harrop, G. A., Jr., and Barron, E. S. G.: J. Clin. Investigation 9:577, 1931. 14. Hueck, W.: Zentralbl. f. Path. u. path. Anat. 36:211, 1925. 15. Thannhauser, S. J.: Lehrbuch des Stoffwechsels und der Stoffwechselkrankheiten , Munich, J. F. Bergmann, 1929. 16. Gardner, J. A., and Gainsborough, H.: Quart. J. Med. 23:465, 1930. 17. Schönheimer, R.: Ztschr. f. physiol. Chem. 185:119, 1929. 18. Schönheimer, R.; von Behring, H.; Hummel, R., and Schindel, L.: Ztschr. f. physiol. Chem. 192:73, 1930. 19. Bürger, M.: Ergeb. d. inn. Med. u. Kinderh. 34:583, 1928. 20. Flint, A., Jr.: Am. J. M. Sc. 44:305, 1862. 21. Chauffard, A.; Laroche, G., and Grigaut, A.: Compt. rend. Soc. de biol. 73:23, 1912. 22. Beumer, H., and Bürger, M.: Ztschr. f. exper. Path. u. Therap. 13:343, 1913. 23. Feigl, J.: Biochem. Ztschr. 90:1, 1918. 24. Bang, I.: Biochem. Ztschr. 91:122, 1918. 25. Stepp, W.: Beitr. z. path. Anat. 69:233, 1921. 26. Rothschild, M. A., and Felsen, J.: The Cholesterol Content of the Blood in Various Hepatic Conditions , Arch. Int. Med. 24:520 ( (Nov.) ) 1919.Crossref 27. Chauffard, A.: La lithiase biliare , ed. 2, Paris, Masson et Cie, 1922. 28. Feigl, J.: Biochem. Ztschr. 86:1, 1918. 29. Thannhauser, S. J., and Schaber, H.: Klin. Wchnschr. 5:252, 1926.Crossref 30. Bürger, M., and Habs, H.: Klin. Wchnschr. 6:2221, 1927.Crossref 31. Stern, R., and Suchantke, G.: Arch. f. exper. Path. u. Pharmakol. 115:221, 1926.Crossref 32. Adler, A., and Lemmel, H.: Deutsches Arch. f. klin. Med. 158:173, 1928. 33. Epstein, E. Z.: The Cholesterol Partition of the Blood Plasma in Parenchymatous Diseases of the Liver , Arch. Int. Med. 47:82 ( (Jan.) ) 1931.Crossref 34. Gardner, J. A., and Gainsborough, H.: Biochem. J. 22:1048, 1928. 35. Bloor, W. R.: J. Biol. Chem. 24:227, 1916. 36. Bloor, W. R., and Knudson, A.: J. Biol. Chem. 27:107, 1916. 37. Eppinger, H.: Beitr. z. path. Anat. u. z. allg. Path. 31:230, 1902. 38. Barron, E. S. G., and Bumstead, J. H.: J. Exper. Med. 47:999, 1928.Crossref 39. Schönheimer, R., and von Behring, H.: Ztschr. f. physiol. Chem. 192:102, 1930. 40. Rothschild, M. A., and Wilensky, A. O.: M. Clin. North America 3:417, 1919. 41. Rothschild, M. A., and Rosenthal, N.: Am. J. M. Sc. 152:394, 1916.Crossref 42. Campbell, J. M. H.: Quart. J. Med. 18:123, 1924Crossref

Journal

Archives of Internal Medicine – American Medical Association

Published: Aug 1, 1932

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