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CHEMISTRY AND METABOLISM IN EXPERIMENTAL YELLOW FEVER IN MACACUS RHESUS MONKEYS: V. ACID-BASE AND ELECTROLYTE EQUILIBRIUM

CHEMISTRY AND METABOLISM IN EXPERIMENTAL YELLOW FEVER IN MACACUS RHESUS MONKEYS: V. ACID-BASE AND... Abstract It has already been pointed out that in the last stages of fatal yellow fever in Macacus rhesus the urinary excretion of organic acid and phosphates is considerably increased.1 In the present paper are reported the results of more extensive studies of the acid-base and electrolyte equilibrium in this disease. METHODS The general experimental procedures outlined in the first paper of this series2 have been carefully followed.The electrolytes of the serum were determined by procedures essentially the same as those described by Peters, Wakeman, Eisenman and Lee.3 Blood was withdrawn and serum separated, with anaerobic precautions, by the technic of Austin and his co-workers.4Blood was collected without stasis from the heart, the femoral artery or the veins of the upper extremities. In certain of the normal animals attempts were made to withdraw venous blood without anesthesia. However, it soon became evident from the low References 1. Wakeman, A. M., and Morrell, C. A.: Chemistry and Metabolism in Experimental Yellow Fever in Macacus Rhesus Monkeys: II. Nitrogen Metabolism , Arch. Int. Med. 46:382 ( (Sept.) ) 1930.Crossref 2. Wakeman, A. M., and Morrell, C. A.: Chemistry and Metabolism in Experimental Yellow Fever in Macacus Rhesus Monkeys: I. Concentration of Nonprotein Nitrogenous Constituents in Blood , Arch. Int. Med. 46:290 ( (Aug.) ) 1930.Crossref 3. Peters, J. P.; Wakeman, A. M.; Eisenman, A. J., and Lee, C.: J. Clin. Investigation 6:517, 1929.Crossref 4. Austin, J. H.; Cullen, G. E.; Hastings, A. B.; McLean, F. C.; Peters, J. P., and Van Slyke, D. D.: J. Biol. Chem. 54: 121, 1922. 5. Bolliger, A., and Maddox, K.: M. J. Australia 1:510, 1930. 6. Chamber, W. H.; Deuel, H. J., Jr., and Milhorat, A. T.: J. Biol. Chem. 75:422, 1927. 7. Van Slyke, D. D., and Neill, J. M.: J. Biol. Chem. 59:523, 1924. 8. Van Slyke, D. D.: J. Biol. Chem. 58:523, 1923. 9. Kramer, B., and Tisdall, F. F.: J. Biol. Chem. 47:475, 1921. 10. Fiske, C. H., and Subbarow, Y.: J. Biol. Chem. 66:375, 1925. 11. Stadie, W. C., and Ross, E. C.: J. Biol. Chem. 65:735, 1925. 12. Howe, J. P.: J. Biol. Chem. 49:93, 1921. 13. Peters, J. P.; Bulger, H. A.; Eisenman, A. J., and Lee, C.: J. Clin. Investigation 2:167, 1925.Crossref 14. Bruckman, F. S.; D'Esopo, L. M., and Peters, J. P.: J. Clin. Investigation 8:577, 1930.Crossref 15. Rowe, A. H.: The Albumin and Globulin Content of Human Blood Serum in Health, Syphilis, Pneumonia and Certain Other Infections , Arch. Int. Med. 18:455 ( (Oct.) ) 1916.Crossref 16. Sunderman, F. W.; Austin, J. H., and Camac, J. G.: J. Clin. Investigation 3:37, 1926.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

CHEMISTRY AND METABOLISM IN EXPERIMENTAL YELLOW FEVER IN MACACUS RHESUS MONKEYS: V. ACID-BASE AND ELECTROLYTE EQUILIBRIUM

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References (10)

Publisher
American Medical Association
Copyright
Copyright © 1932 American Medical Association. All Rights Reserved.
ISSN
0730-188X
DOI
10.1001/archinte.1932.00150120116011
Publisher site
See Article on Publisher Site

Abstract

Abstract It has already been pointed out that in the last stages of fatal yellow fever in Macacus rhesus the urinary excretion of organic acid and phosphates is considerably increased.1 In the present paper are reported the results of more extensive studies of the acid-base and electrolyte equilibrium in this disease. METHODS The general experimental procedures outlined in the first paper of this series2 have been carefully followed.The electrolytes of the serum were determined by procedures essentially the same as those described by Peters, Wakeman, Eisenman and Lee.3 Blood was withdrawn and serum separated, with anaerobic precautions, by the technic of Austin and his co-workers.4Blood was collected without stasis from the heart, the femoral artery or the veins of the upper extremities. In certain of the normal animals attempts were made to withdraw venous blood without anesthesia. However, it soon became evident from the low References 1. Wakeman, A. M., and Morrell, C. A.: Chemistry and Metabolism in Experimental Yellow Fever in Macacus Rhesus Monkeys: II. Nitrogen Metabolism , Arch. Int. Med. 46:382 ( (Sept.) ) 1930.Crossref 2. Wakeman, A. M., and Morrell, C. A.: Chemistry and Metabolism in Experimental Yellow Fever in Macacus Rhesus Monkeys: I. Concentration of Nonprotein Nitrogenous Constituents in Blood , Arch. Int. Med. 46:290 ( (Aug.) ) 1930.Crossref 3. Peters, J. P.; Wakeman, A. M.; Eisenman, A. J., and Lee, C.: J. Clin. Investigation 6:517, 1929.Crossref 4. Austin, J. H.; Cullen, G. E.; Hastings, A. B.; McLean, F. C.; Peters, J. P., and Van Slyke, D. D.: J. Biol. Chem. 54: 121, 1922. 5. Bolliger, A., and Maddox, K.: M. J. Australia 1:510, 1930. 6. Chamber, W. H.; Deuel, H. J., Jr., and Milhorat, A. T.: J. Biol. Chem. 75:422, 1927. 7. Van Slyke, D. D., and Neill, J. M.: J. Biol. Chem. 59:523, 1924. 8. Van Slyke, D. D.: J. Biol. Chem. 58:523, 1923. 9. Kramer, B., and Tisdall, F. F.: J. Biol. Chem. 47:475, 1921. 10. Fiske, C. H., and Subbarow, Y.: J. Biol. Chem. 66:375, 1925. 11. Stadie, W. C., and Ross, E. C.: J. Biol. Chem. 65:735, 1925. 12. Howe, J. P.: J. Biol. Chem. 49:93, 1921. 13. Peters, J. P.; Bulger, H. A.; Eisenman, A. J., and Lee, C.: J. Clin. Investigation 2:167, 1925.Crossref 14. Bruckman, F. S.; D'Esopo, L. M., and Peters, J. P.: J. Clin. Investigation 8:577, 1930.Crossref 15. Rowe, A. H.: The Albumin and Globulin Content of Human Blood Serum in Health, Syphilis, Pneumonia and Certain Other Infections , Arch. Int. Med. 18:455 ( (Oct.) ) 1916.Crossref 16. Sunderman, F. W.; Austin, J. H., and Camac, J. G.: J. Clin. Investigation 3:37, 1926.Crossref

Journal

Archives of Internal MedicineAmerican Medical Association

Published: May 1, 1932

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