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G. Shwartzman (1929)
STUDIES ON BACILLUS TYPHOSUS TOXIC SUBSTANCESThe Journal of Experimental Medicine, 49
E. Ecker, Ann Welch (1930)
CUTANEOUS REACTIONS WITH CULTURE FILTRATES OF THE COLON TYPHOID TYPEThe Journal of Experimental Medicine, 51
G. Shwartzman (1929)
Ammonium Sulphate Precipitation of Bacillus Typhosus Toxic Subtances in the Phenomenon of Local Skin ReactivityThe Journal of Infectious Diseases, 45
S. Herrmann (1929)
EXPERIMENTAL PERITONITIS AND PERITONEAL IMMUNITYArchives of Surgery, 18
B. Steinberg, H. Goldblatt (1928)
PERITONITIS: IV. PRODUCTION OF ACTIVE IMMUNITY AGAINST THE FATAL OUTCOME OF EXPERIMENTAL FECAL PERITONITISJAMA Internal Medicine, 42
Abstract The conception of local immunity, i.e., the locally increased resistance of a tissue or organ without the participation of the organism as a whole, is not a new one. It has long been recognized that the tissue cell, as the ultimate functional body unit, must be the source from which originate the various protective constituents of normal and immune serums, and that it must be in these cells that the primary changes of the processes known as immunization take place. In support of this view there are both clinical and experimental data; of the former, one notes, for example, the occurrence of crops of furuncles in widely different parts of a patient's skin, one crop healing only to have another crop arise; there the process of limitation and healing of the infected foci is surely not due to any generalized resistance, but rather to local causes. On the experimental side References 1. Romer, P.: Arch. f. Ophth. 52:72, 1901. 2. Kraus, T., and Volk, R.: Wien. klin. Wchnschr. 19:620, 1906. 3. Wassermann, A., and Citron, J.: Ztschr. f. Hyg. 50:331, 1905.Crossref 4. Besredka, A.: Local Immunization (translated by Harry Plotz), Baltimore, Williams & Wilkins Company, 1927. 5. Gay, F. P.: Local or Tissue Immunity, Arch. Path. 1:590 ( (April) ) 1926. 6. Steinberg, B., and Goldblatt, H.: Peritonitis: IV. Production of Active Immunity Against the Fatal Outcome of Experimental Fecal Peritonitis , Arch. Int. Med. 42:415 ( (Sept.) ) 1928.Crossref 7. Herrmann, S. F:. Experimental Peritonitis and Peritoneal Immunity , Arch. Surg. 18:2202 ( (May) ) 1929.Crossref 8. Shwartzman, G.: Proc. Soc. Exper. Biol. & Med. 25:560, 1928 9. J. Exper. Med. 48:245, 1928 10. Proc. Soc. Exper. Biol. & Med. 26:131, 1928 11. J. Exper. Med. 49:593, 1929 12. Proc. Soc. Exper. Biol. & Med. 26:207, 1928 13. Proc. Soc. Exper. Biol. & Med. 26:843, 1929 14. J. Infect. Dis. 45:283, 1929 15. J. Exper. Med. 50:513, 1929 16. J. Exper. Med. 192950513, to be published. 17. Hangar, F. M.: Proc. Soc. Exper. Biol. & Med. 25:775, 1928. 18. Ecker, E. E., and Welch, H.: J. Exper. Med. 51:409, 1930. 19. The factors which induced the local skin reactivity are termed "Skin Preparatory Factors" and those involved in production of local hemorrhagic reactions following the intravenous injections, "Reacting Factors."
Archives of Internal Medicine – American Medical Association
Published: Sep 1, 1930
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