Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

DEMONSTRATION OF LOCAL IMMUNITY OF THE PERITONEUM BY MEANS OF THE SHWARTZMAN PHENOMENON

DEMONSTRATION OF LOCAL IMMUNITY OF THE PERITONEUM BY MEANS OF THE SHWARTZMAN PHENOMENON Abstract The conception of local immunity, i.e., the locally increased resistance of a tissue or organ without the participation of the organism as a whole, is not a new one. It has long been recognized that the tissue cell, as the ultimate functional body unit, must be the source from which originate the various protective constituents of normal and immune serums, and that it must be in these cells that the primary changes of the processes known as immunization take place. In support of this view there are both clinical and experimental data; of the former, one notes, for example, the occurrence of crops of furuncles in widely different parts of a patient's skin, one crop healing only to have another crop arise; there the process of limitation and healing of the infected foci is surely not due to any generalized resistance, but rather to local causes. On the experimental side References 1. Romer, P.: Arch. f. Ophth. 52:72, 1901. 2. Kraus, T., and Volk, R.: Wien. klin. Wchnschr. 19:620, 1906. 3. Wassermann, A., and Citron, J.: Ztschr. f. Hyg. 50:331, 1905.Crossref 4. Besredka, A.: Local Immunization (translated by Harry Plotz), Baltimore, Williams & Wilkins Company, 1927. 5. Gay, F. P.: Local or Tissue Immunity, Arch. Path. 1:590 ( (April) ) 1926. 6. Steinberg, B., and Goldblatt, H.: Peritonitis: IV. Production of Active Immunity Against the Fatal Outcome of Experimental Fecal Peritonitis , Arch. Int. Med. 42:415 ( (Sept.) ) 1928.Crossref 7. Herrmann, S. F:. Experimental Peritonitis and Peritoneal Immunity , Arch. Surg. 18:2202 ( (May) ) 1929.Crossref 8. Shwartzman, G.: Proc. Soc. Exper. Biol. & Med. 25:560, 1928 9. J. Exper. Med. 48:245, 1928 10. Proc. Soc. Exper. Biol. & Med. 26:131, 1928 11. J. Exper. Med. 49:593, 1929 12. Proc. Soc. Exper. Biol. & Med. 26:207, 1928 13. Proc. Soc. Exper. Biol. & Med. 26:843, 1929 14. J. Infect. Dis. 45:283, 1929 15. J. Exper. Med. 50:513, 1929 16. J. Exper. Med. 192950513, to be published. 17. Hangar, F. M.: Proc. Soc. Exper. Biol. & Med. 25:775, 1928. 18. Ecker, E. E., and Welch, H.: J. Exper. Med. 51:409, 1930. 19. The factors which induced the local skin reactivity are termed "Skin Preparatory Factors" and those involved in production of local hemorrhagic reactions following the intravenous injections, "Reacting Factors." http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

DEMONSTRATION OF LOCAL IMMUNITY OF THE PERITONEUM BY MEANS OF THE SHWARTZMAN PHENOMENON

Archives of Internal Medicine , Volume 46 (3) – Sep 1, 1930

Loading next page...
 
/lp/american-medical-association/demonstration-of-local-immunity-of-the-peritoneum-by-means-of-the-OLlrhuzA9g

References (5)

Publisher
American Medical Association
Copyright
Copyright © 1930 American Medical Association. All Rights Reserved.
ISSN
0730-188X
DOI
10.1001/archinte.1930.00140150051005
Publisher site
See Article on Publisher Site

Abstract

Abstract The conception of local immunity, i.e., the locally increased resistance of a tissue or organ without the participation of the organism as a whole, is not a new one. It has long been recognized that the tissue cell, as the ultimate functional body unit, must be the source from which originate the various protective constituents of normal and immune serums, and that it must be in these cells that the primary changes of the processes known as immunization take place. In support of this view there are both clinical and experimental data; of the former, one notes, for example, the occurrence of crops of furuncles in widely different parts of a patient's skin, one crop healing only to have another crop arise; there the process of limitation and healing of the infected foci is surely not due to any generalized resistance, but rather to local causes. On the experimental side References 1. Romer, P.: Arch. f. Ophth. 52:72, 1901. 2. Kraus, T., and Volk, R.: Wien. klin. Wchnschr. 19:620, 1906. 3. Wassermann, A., and Citron, J.: Ztschr. f. Hyg. 50:331, 1905.Crossref 4. Besredka, A.: Local Immunization (translated by Harry Plotz), Baltimore, Williams & Wilkins Company, 1927. 5. Gay, F. P.: Local or Tissue Immunity, Arch. Path. 1:590 ( (April) ) 1926. 6. Steinberg, B., and Goldblatt, H.: Peritonitis: IV. Production of Active Immunity Against the Fatal Outcome of Experimental Fecal Peritonitis , Arch. Int. Med. 42:415 ( (Sept.) ) 1928.Crossref 7. Herrmann, S. F:. Experimental Peritonitis and Peritoneal Immunity , Arch. Surg. 18:2202 ( (May) ) 1929.Crossref 8. Shwartzman, G.: Proc. Soc. Exper. Biol. & Med. 25:560, 1928 9. J. Exper. Med. 48:245, 1928 10. Proc. Soc. Exper. Biol. & Med. 26:131, 1928 11. J. Exper. Med. 49:593, 1929 12. Proc. Soc. Exper. Biol. & Med. 26:207, 1928 13. Proc. Soc. Exper. Biol. & Med. 26:843, 1929 14. J. Infect. Dis. 45:283, 1929 15. J. Exper. Med. 50:513, 1929 16. J. Exper. Med. 192950513, to be published. 17. Hangar, F. M.: Proc. Soc. Exper. Biol. & Med. 25:775, 1928. 18. Ecker, E. E., and Welch, H.: J. Exper. Med. 51:409, 1930. 19. The factors which induced the local skin reactivity are termed "Skin Preparatory Factors" and those involved in production of local hemorrhagic reactions following the intravenous injections, "Reacting Factors."

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Sep 1, 1930

There are no references for this article.