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THE PATHOLOGY OF PNEUMONIA CAUSED BY BACILLUS INFLUENZAE DURING AN INTEREPIDEMIC PERIOD

THE PATHOLOGY OF PNEUMONIA CAUSED BY BACILLUS INFLUENZAE DURING AN INTEREPIDEMIC PERIOD Abstract The frequent association of Bacillus influenzae with the respiratory discharges and with the pneumonias which accompanied the pandemic of influenza, in 1918, gave an apparently reasonable foundation to the hypothesis that this bacillus was the etiologic agent of the initial disease. This assumption seemed at first the more acceptable in view of Pfeiffer's1 discovery of the influenza bacillus in association with influenza during recurrences of the previous epidemic of 1889-1890, and his pronouncement that it was the cause of the disease. Bacteriologic and pathologic studies made during and after the last outbreak, however, make it very doubtful that the influenza bacillus was more than a secondary invader associated with an as yet unknown virus of influenza. It was soon found that while Bacillus influenzae was frequently a contributing cause of the pneumonia present in fatal cases, this bacillus was by no means universally in evidence, and there seemed to be References 1. Pfeiffer, R.: Ztschr. f. Hyg. u. Infectionskrankh. 13:3, 1893. 2. MacCallum, W. G.: Monograph of the Rockefeller Institute for Medical Research, No. 10, 1919 3. Reports Johns Hopkins Hosp. 20:149 (Part (II) ) 1921. 4. Wolbach, S. B.: Bull. Johns Hopkins Hosp. 30:104 ( (April) ) 1919. 5. Goodpasture, E. W., and Burnett, F. L.: U. S. Nav. M. Bull. 13:177 ( (April) ) 1919. 6. Wolbach, S. B., and Frothingham, C.: Influenza Epidemic at Camp Devans in 1918 7. Study of Pathology of Fatal Cases , Arch. Int. Med. 32:571 ( (Oct.) ) 1923.Crossref 8. Goodpasture, E. W.: Am. J. Med. Sc. 158:863 ( (Dec.) ) 1919.Crossref 9. Davis, D. J.: Influenza and Influenzal Pneumonia , Arch. Int. Med. 2:124 ( (Sept.) ) 1908Crossref 10. J. Inf. Dis. 10:259, 1912.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

THE PATHOLOGY OF PNEUMONIA CAUSED BY BACILLUS INFLUENZAE DURING AN INTEREPIDEMIC PERIOD

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References (4)

Publisher
American Medical Association
Copyright
Copyright © 1924 American Medical Association. All Rights Reserved.
ISSN
0730-188X
DOI
10.1001/archinte.1924.00120060002001
Publisher site
See Article on Publisher Site

Abstract

Abstract The frequent association of Bacillus influenzae with the respiratory discharges and with the pneumonias which accompanied the pandemic of influenza, in 1918, gave an apparently reasonable foundation to the hypothesis that this bacillus was the etiologic agent of the initial disease. This assumption seemed at first the more acceptable in view of Pfeiffer's1 discovery of the influenza bacillus in association with influenza during recurrences of the previous epidemic of 1889-1890, and his pronouncement that it was the cause of the disease. Bacteriologic and pathologic studies made during and after the last outbreak, however, make it very doubtful that the influenza bacillus was more than a secondary invader associated with an as yet unknown virus of influenza. It was soon found that while Bacillus influenzae was frequently a contributing cause of the pneumonia present in fatal cases, this bacillus was by no means universally in evidence, and there seemed to be References 1. Pfeiffer, R.: Ztschr. f. Hyg. u. Infectionskrankh. 13:3, 1893. 2. MacCallum, W. G.: Monograph of the Rockefeller Institute for Medical Research, No. 10, 1919 3. Reports Johns Hopkins Hosp. 20:149 (Part (II) ) 1921. 4. Wolbach, S. B.: Bull. Johns Hopkins Hosp. 30:104 ( (April) ) 1919. 5. Goodpasture, E. W., and Burnett, F. L.: U. S. Nav. M. Bull. 13:177 ( (April) ) 1919. 6. Wolbach, S. B., and Frothingham, C.: Influenza Epidemic at Camp Devans in 1918 7. Study of Pathology of Fatal Cases , Arch. Int. Med. 32:571 ( (Oct.) ) 1923.Crossref 8. Goodpasture, E. W.: Am. J. Med. Sc. 158:863 ( (Dec.) ) 1919.Crossref 9. Davis, D. J.: Influenza and Influenzal Pneumonia , Arch. Int. Med. 2:124 ( (Sept.) ) 1908Crossref 10. J. Inf. Dis. 10:259, 1912.Crossref

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Dec 1, 1924

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