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E. Brunemeier, A. Carlson
CONTRIBUTIONS TO THE PHYSIOLOGY OF THE STOMACH: XIX. Reflexes from the Intestinal Mucosa to the StomachAmerican Journal of Physiology, 36
L. Hardt (1916)
CONTRIBUTIONS TO THE PHYSIOLOGY OF THE STOMACHAmerican Journal of Physiology, 40
E. Rosenow (1916)
The Causation of Gastric and Duodenal Ulcer by Streptococci Plates 5 TO 14The Journal of Infectious Diseases, 19
A. Carlson (1913)
CONTRIBUTIONS TO THE PHYSIOLOGY OF THE STOMACH: VI. A Study of the Mechanisms of the Hunger Contractions of the Empty Stomach by Experiments on DogsAmerican Journal of Physiology, 32
W. Osler (1892)
The Principles and Practice of MedicineThe Southern Medical Record, 22
A. Carlson (1916)
The Control of Hunger in Health and DiseaseThe Psychological Clinic, 10
Abstract The studies on gastric ulcer as presented here are the first of a series of studies on the pathologic physiology of the stomach and duodenum in the condition of ulcer of these parts of the gastrointestinal tract. I. THE OCCURENCE OF ULCER AND OTHER PATHOLOGIC LESIONS IN THE STOMACH AND THE DUODENUM OF THE DOG AS JUDGED FROM ONE THOUSAND NECROPSIES In a series of studies to be made on a pathologic physiologic condition it is obviously essential to make a study of the frequency of the occurrence of that condition in the animal used. A large amount of work has been done on gastric ulcer in which the dog has been the chief experimental animal. There are only two reports in the literature concerning the frequency of the occurrence of ulcer in the dog. Turck1 reports a series of necropsies on 189 healthy and 82 diseased dogs in which References 1. Turck, F. B.: J. A. M. A. 67:1784 ( (Dec. 9) ) 1916. 2. Mann, F. C.: J. Exper. M. 23:203 ( (Feb.) ) 1916.Crossref 3. Bolton: Quart. J. Med. 5:434, 1911. 4. Food was present in the stomachs of about one half of the animals. The lesions had no relation to the presence of food, however. 5. Carlson, A. J.: Am. J. Physiol. 30: 1912. 6. Jona, J. L.: M. J. Australia 1:316 ( (April 19) ) 1919. 7. Durante, L.: Surg., Gyn., Obst. 22:399 ( (April) ) 1916. 8. In an emaciated dog with gastrostomy and both splanchnics cut, Dr. A. B. Luckhardt found a chronic ulcer about one inch from the gastrostomy. The ulcer was about to perforate. 9. Adami, J.: Principles of Pathology , Philadelphia, Lea & Febiger, 1911, 2: 414. 10. Birch-Hirschfeld: loc. cit., Adami. 11. Osler, W.: The Principles and Practice of Medicine , New York, D. Appleton & Co., 1916, pp. 490, 447, 480. 12. Robson, A. W. M.: Lancet 2:1547, 1904. 13. Wilson, L., and McCarthy, W. C.: Am. J. M. Sc. , 846 ( (Dec.) ) 1909. 14. Bolton: Proc. Roy. Soc., Lond. 82:236, 1909. 15. Friedman, J. C., and Hamburger, W. W.: J. A. M. A. 62:380 ( (Aug. 1) ) 1914.Crossref 16. Rosenow, E. C.: J. Infect. Dis. 19:333 ( (Sept.) ) 1916.Crossref 17. Bolton: Ulcer of the Stomach , London, 1913. 18. Griffini and Vassale: Ziegler's Beitr. 3:425. 19. Cohnheim: Lect. on Gen. Path. (New Sydenham Soc.) 3:878, 1890. 20. Klebs and Welti: Handb. d. path. Anat. , 1869. 21. Littauer: Virch. Arch. 195: No. (2) , 328. 22. Wilkensky, A. O., and Geist, S. H.: J. A. M. A. 66:1382 ( (April 29) ), 1916.Crossref 23. Rosenow, Jour. Infect. Dis. 17:219, 1915.Crossref 24. Hardt, L. L. J.: Am. J. Physiol. 40:314 ( (April) ) 1916. 25. Dragstedt, L. R.: J. A. M. A. 68:330 ( (Feb. 3) ) 1917.Crossref 26. Dundon, J. R.: Am. J. Physiol. 44:234 ( (Sept.) ) 1917. 27. The amount of air required is practically constant from day to day, never varying more than 5 c.c. There is quite a variation between different dogs, varying from 15 to 40 c.c. After section of the vagi the amount required is from 10 to 20 c.c. more than normal. This is only temporary; after from ten to twelve days the amount required becomes normal again. It is a question whether this is a true measure of the postural or tonic activity of the stomach. It points in that direction, however. The normal amount required is not influenced by ulcer of the stomach or duodenum. For a day or two after making the ulcer the amount required may be from 5 to 10 c.c. below normal, however. 28. Luckhardt: loc. cit. 29. Carlson, The Control of Hunger in Health and Disease , Chicago, 1916. 30. Carlson, A. J.: Am. J. Physiol. 32:369, 1913. 31. Cannon, W. B.: Am. J. Physiol. 36:191, 1915. 32. Brunemeier and Carlson: Am. J. Physiol. 36:191, 1915. 33. Hicks and Vischer: Am. J. Physiol. 39:1, 1915. 34. Carman, R. D.: J. A. M. A. 66:1283 ( (April 22) ) 1916.Crossref
Archives of Internal Medicine – American Medical Association
Published: Jan 1, 1920
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