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CHRONIC CAPILLARY CYANOSIS

CHRONIC CAPILLARY CYANOSIS Abstract Although general clinical conceptions of the mechanism of cyanosis are vague, it has long been recognized that it may be due to four main causes: (1) deficient oxygenation of the blood; (2) obstruction to normal flow in the capillaries; (3) combinations of 1 and 2, and (4) chemical transformation of the hemoglobin. Demonstration of the mechanism of the form arising in the capillaries, has, so far as we have been able to determine, not been made and it is conceivable that it might prove important from the standpoint of diagnosis in obscure cases. The first question to decide in such a case would be whether the cyanosis could be due to insufficient oxygenation of the blood. In this connection it is well to emphasize, as Hoover1 has recently done, that cyanosis arising in the thorax is always due to the passage of venous blood to the left heart. In pneumonia References 1. Hoover, C. F.: Moisture in the Air Spaces of the Lungs and Oxygen Therapy , J. A. M. A. , 71:880, 1918.Crossref 2. Peabody, F. W., and Wentworth, J. A.: Clinical Studies of the Respiration. IV. The Vital Capacity of the Lungs and its Relation to Dyspnea , Archives Int. Med. , 20:443, 1917.Crossref 3. Cannon, W. B.; Fraser, J., and Hooper, A. N.: Some Alterations in Distribution and Character of Blood in Shock and Hemorrhage , J. A. M. A. , 70:526, 1918. 4. Bence, J.: Klinische Untersuchungen uber die Viskositát des Blutes , Ztschr. f. klin. Med. , 58:203, 1906. 5. Van Slyke, D. D.: Gasometric Determination of the Oxygen and Hemoglobin of Blood , J. Biol. Chem. , 33:127, 1916. 6. Lundsgaard, C.: Studies of Oxygen in the Venous Blood , J. Biol. Chem. , 33:133. 7. Peabody, F. W.; Meyer, A. L., and DuBois, E. F.: The Basal Metabolism of Patients with Cardiac and Renal Disease , Archives Int. Med. , 17:981, 1916. 8. Palmer, W. W.: Colorimetric Determination of Hemoglobin , J. Biol. Chem. , 33:119. 9. Fredericia, L. S.: Eine klinische Methode zur Bestimmung der Kohlensaurenspannung in der Lungenleft , Berl. klin. Wchnschr. , 51:1268, 1914. 10. Van Slyke, D. D., and Cullen, G. E.: The Bicarbonate Concentration of the Blood Plasma, Its Significance and Its Determination as a Measure of Acidosis , J. Biol. Chem. , 30:289. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

CHRONIC CAPILLARY CYANOSIS

Archives of Internal Medicine , Volume 23 (1) – Jan 1, 1919

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References (14)

Publisher
American Medical Association
Copyright
Copyright © 1919 American Medical Association. All Rights Reserved.
ISSN
0730-188X
DOI
10.1001/archinte.1919.00090180061004
Publisher site
See Article on Publisher Site

Abstract

Abstract Although general clinical conceptions of the mechanism of cyanosis are vague, it has long been recognized that it may be due to four main causes: (1) deficient oxygenation of the blood; (2) obstruction to normal flow in the capillaries; (3) combinations of 1 and 2, and (4) chemical transformation of the hemoglobin. Demonstration of the mechanism of the form arising in the capillaries, has, so far as we have been able to determine, not been made and it is conceivable that it might prove important from the standpoint of diagnosis in obscure cases. The first question to decide in such a case would be whether the cyanosis could be due to insufficient oxygenation of the blood. In this connection it is well to emphasize, as Hoover1 has recently done, that cyanosis arising in the thorax is always due to the passage of venous blood to the left heart. In pneumonia References 1. Hoover, C. F.: Moisture in the Air Spaces of the Lungs and Oxygen Therapy , J. A. M. A. , 71:880, 1918.Crossref 2. Peabody, F. W., and Wentworth, J. A.: Clinical Studies of the Respiration. IV. The Vital Capacity of the Lungs and its Relation to Dyspnea , Archives Int. Med. , 20:443, 1917.Crossref 3. Cannon, W. B.; Fraser, J., and Hooper, A. N.: Some Alterations in Distribution and Character of Blood in Shock and Hemorrhage , J. A. M. A. , 70:526, 1918. 4. Bence, J.: Klinische Untersuchungen uber die Viskositát des Blutes , Ztschr. f. klin. Med. , 58:203, 1906. 5. Van Slyke, D. D.: Gasometric Determination of the Oxygen and Hemoglobin of Blood , J. Biol. Chem. , 33:127, 1916. 6. Lundsgaard, C.: Studies of Oxygen in the Venous Blood , J. Biol. Chem. , 33:133. 7. Peabody, F. W.; Meyer, A. L., and DuBois, E. F.: The Basal Metabolism of Patients with Cardiac and Renal Disease , Archives Int. Med. , 17:981, 1916. 8. Palmer, W. W.: Colorimetric Determination of Hemoglobin , J. Biol. Chem. , 33:119. 9. Fredericia, L. S.: Eine klinische Methode zur Bestimmung der Kohlensaurenspannung in der Lungenleft , Berl. klin. Wchnschr. , 51:1268, 1914. 10. Van Slyke, D. D., and Cullen, G. E.: The Bicarbonate Concentration of the Blood Plasma, Its Significance and Its Determination as a Measure of Acidosis , J. Biol. Chem. , 30:289.

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Jan 1, 1919

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