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D. Slyke
GASOMETRIC DETERMINATION OF THE OXYGEN AND HEMOGLOBIN OF BLOODJournal of Biological Chemistry, 33
J. Bence (1906)
Klinische Untersuchungen uber die Viskosit�t des BlutesZtschr. f. klin. Med., 58
F. W. Peabody , A. L. Meyer (1916)
The Basal Metabolism of Patients with Cardiac and Renal DiseaseArchives Int. Med., 17
C. Hoover (1918)
MOISTURE IN THE AIR SPACES OF THE LUNGS AND OXYGEN THERAPYJAMA, 71
D. Slyke, G. Cullen (1917)
STUDIES OF ACIDOSIS I. THE BICARBONATE CONCENTRATION OF THE BLOOD PLASMA; ITS SIGNIFICANCE, AND ITS DETERMINATION AS A MEASURE OF ACIDOSISJournal of Biological Chemistry, 30
F. Peabody, J. Wentworth (1917)
CLINICAL STUDIES OF THE RESPIRATION: IV. THE VITAL CAPACITY OF THE LUNGS AND ITS RELATION TO DYSPNEAJAMA Internal Medicine
W. Palmer
THE COLORIMETRIC DETERMINATION OF HEMOGLOBINJournal of Biological Chemistry, 33
W. B. Cannon , J. Fraser (1918)
Some Alterations in Distribution and Character of Blood in Shock and HemorrhageJ. A. M. A., 70
C. Lundsgaard
STUDIES OF OXYGEN IN THE VENOUS BLOOD I. TECHNIQUE AND RESULTS ON NORMAL INDIVIDUALSJournal of Biological Chemistry, 33
D. D. Van Slyke
The Bicarbonate Concentration of the Blood Plasma, Its Significance and Its Determination as a Measure of AcidosisJ. Biol. Chem., 30
C. Lundsgaard
Studies of Oxygen in the Venous BloodJ. Biol. Chem., 33
F. W. Peabody (1917)
Clinical Studies of the Respiration. IV. The Vital Capacity of the Lungs and its Relation to DyspneaArchives Int. Med., 20
C. Lundsgaard (1919)
STUDIES OF OXYGEN IN THE VENOUS BLOODThe Journal of Experimental Medicine, 30
L. S. Fredericia (1914)
Eine klinische Methode zur Bestimmung der Kohlensaurenspannung in der LungenleftBerl. klin. Wchnschr., 51
Abstract Although general clinical conceptions of the mechanism of cyanosis are vague, it has long been recognized that it may be due to four main causes: (1) deficient oxygenation of the blood; (2) obstruction to normal flow in the capillaries; (3) combinations of 1 and 2, and (4) chemical transformation of the hemoglobin. Demonstration of the mechanism of the form arising in the capillaries, has, so far as we have been able to determine, not been made and it is conceivable that it might prove important from the standpoint of diagnosis in obscure cases. The first question to decide in such a case would be whether the cyanosis could be due to insufficient oxygenation of the blood. In this connection it is well to emphasize, as Hoover1 has recently done, that cyanosis arising in the thorax is always due to the passage of venous blood to the left heart. In pneumonia References 1. Hoover, C. F.: Moisture in the Air Spaces of the Lungs and Oxygen Therapy , J. A. M. A. , 71:880, 1918.Crossref 2. Peabody, F. W., and Wentworth, J. A.: Clinical Studies of the Respiration. IV. The Vital Capacity of the Lungs and its Relation to Dyspnea , Archives Int. Med. , 20:443, 1917.Crossref 3. Cannon, W. B.; Fraser, J., and Hooper, A. N.: Some Alterations in Distribution and Character of Blood in Shock and Hemorrhage , J. A. M. A. , 70:526, 1918. 4. Bence, J.: Klinische Untersuchungen uber die Viskositát des Blutes , Ztschr. f. klin. Med. , 58:203, 1906. 5. Van Slyke, D. D.: Gasometric Determination of the Oxygen and Hemoglobin of Blood , J. Biol. Chem. , 33:127, 1916. 6. Lundsgaard, C.: Studies of Oxygen in the Venous Blood , J. Biol. Chem. , 33:133. 7. Peabody, F. W.; Meyer, A. L., and DuBois, E. F.: The Basal Metabolism of Patients with Cardiac and Renal Disease , Archives Int. Med. , 17:981, 1916. 8. Palmer, W. W.: Colorimetric Determination of Hemoglobin , J. Biol. Chem. , 33:119. 9. Fredericia, L. S.: Eine klinische Methode zur Bestimmung der Kohlensaurenspannung in der Lungenleft , Berl. klin. Wchnschr. , 51:1268, 1914. 10. Van Slyke, D. D., and Cullen, G. E.: The Bicarbonate Concentration of the Blood Plasma, Its Significance and Its Determination as a Measure of Acidosis , J. Biol. Chem. , 30:289.
Archives of Internal Medicine – American Medical Association
Published: Jan 1, 1919
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