Access the full text.
Sign up today, get DeepDyve free for 14 days.
J. Means (1915)
Studies of the Basal Metabolism in Obesity and Pituitary Disease.The Journal of medical research, 32 1
Benedict and Emmes (1915)
Comparison of the Metabolism of Normal Men and WomenJour. Biol. Chem., xx
E. Bois (1916)
THE RESPIRATION CALORIMETER IN CLINICAL MEDICNINEThe American Journal of the Medical Sciences, 151
D. DuBois (1915)
Measurement of the Surface Area of ManThe Archives Int. Med., xv
J. H. Means (1915)
Basal Metabolism and Body SurfaceJour. Biol. Chem., xxi
Abstract A year ago I reported some observations of the gaseous metabolism in four cases of obesity and one of acromegaly.1 At present I wish to discuss the findings in these cases somewhat further, and at the same time to report observations on eight new cases.2 The object in view has been to determine whether any gross disturbances in the metabolism as shown by the basal gas exchange occur in obesity. The method has been described in the previous paper and consists, briefly, in the determination of the gas exchange in the nüchtern subject, lying prone, in a moderately warm room, and the calculation of the heat production by indirect calorimetry from the oxygen absorption and the calorific value of oxygen for the respiratory quotient obtained.3 In judging of the normality of any given metabolism the body surface is unquestionably a better criterion than the References 1. Means, J. H.: Studies of the Basal Metabolism in Obesity and Pituitary Disease , Jour. Med. Research , 1915, xxvii, 121. 2. I shall take this opportunity to correct three errors in the previous paper. In the first place Mrs. McK.'s height was incorrectly given. It should have been 144.5 cm. In Table 5, page 133, a cipher should be added to the figures for alveolar ventilation. Lastly, an error was made in measuring N. K. This was called to my attention by Dr. DuBois. The subject was not available so I could not remeasure him, but I have calculated his probable area as shown in Table 2 of the present paper. This correction lowers the figure for his metabolism from 43.1 to 36.4 calories per square meter and hour. 3. When the respiratory quotient was below 0.70 the calorific value for 0.70 was used. 4. Means, J. H.: Basal Metabolism and Body Surface , Jour. Biol. Chem. , 1915, xxi, 263. 5. DuBois, D., and E. F.: Measurement of the Surface Area of Man , The Archives Int. Med. , 1915, xv, 868.Crossref 6. In measuring obese subjects the results obtained by the linear formula are undoubtedly less accurate than in persons of normal build. On Feb. 9, 1916, Dr. F. G. Benedict and I both measured Mrs. McK. Dr. Benedict's measurements gave an area of 2.37 square meters ; mine, 2.12 square meters. She weighed at that time 99 kg. The difficulty lies in making the same amount of traction in taking the circumferences, and in locating some of the bony landmarks. Nevertheless the linear formula is more accurate than any other method available, except the actual measurement of casts or molds of the body. 7. DuBois, E. F.: The Respiration Calorimeter in Clinical Medicine , Harvey Lecture, (Nov. 27) , 1915. 8. Benedict and Emmes : Comparison of the Metabolism of Normal Men and Women , Jour. Biol. Chem. , 1915, xx, 253.
Archives of Internal Medicine – American Medical Association
Published: May 1, 1916
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.