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THE RELATION OF CALCIUM TO THE DELAYED COAGULATION OF BLOOD IN OBSTRUCTIVE JAUNDICE

THE RELATION OF CALCIUM TO THE DELAYED COAGULATION OF BLOOD IN OBSTRUCTIVE JAUNDICE Abstract It has long been recognized that in certain cases of obstructive jaundice there is a tendency to hemorrhage due to the delayed coagulation of the blood. Morawitz and Bierich1 studied the causes of bleeding in cholemia and came to the conclusion that the altered coagulation time in these cases could be traced to delayed formation of fibrin ferment. They attributed this delay to a diminution or absence of thrombokinase. They believed that the altered coagulation time was not due to the presence of cholates or biliary acids in the blood and was independent of the duration or intensity of the jaundice. Kunika2 investigated the clinical value of the determination of the coagulation time in cases of icterus and concluded that the delay was due to a decrease in the liver function. King and Stewart,3 in the course of an investigation of the cause of References 1. Morawitz and Bierich: Arch f. exper. Path. u. Pharmakol. , 1907, lvi, 115. 2. Kunika, S.: Deutsch. Ztschr. f. Chir. , 1912, cxviii, 574.Crossref 3. King and Stewart: Jour. Exper. Med. , 1909, xi, 673.Crossref 4. King, Bigelow and Pearce: Jour. Exper. Med. , 1911, xiv, 159. 5. Lee, Roger I., and Vincent, Beth: The Coagulation of Normal Human Blood , The Archives Int. Med. , 1914, xiii, 398.Crossref 6. Lee and White: Am. Jour. Med. Sc. , 1913, cxlv, 495.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

THE RELATION OF CALCIUM TO THE DELAYED COAGULATION OF BLOOD IN OBSTRUCTIVE JAUNDICE

LEE, ROGER I.; VINCENT, BETH
Archives of Internal Medicine , Volume XVI (1) – Jul 1, 1915
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References (1)

Publisher
American Medical Association
Copyright
Copyright © 1915 American Medical Association. All Rights Reserved.
ISSN
0730-188X
DOI
10.1001/archinte.1915.00080010064005
Publisher site
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Abstract

Abstract It has long been recognized that in certain cases of obstructive jaundice there is a tendency to hemorrhage due to the delayed coagulation of the blood. Morawitz and Bierich1 studied the causes of bleeding in cholemia and came to the conclusion that the altered coagulation time in these cases could be traced to delayed formation of fibrin ferment. They attributed this delay to a diminution or absence of thrombokinase. They believed that the altered coagulation time was not due to the presence of cholates or biliary acids in the blood and was independent of the duration or intensity of the jaundice. Kunika2 investigated the clinical value of the determination of the coagulation time in cases of icterus and concluded that the delay was due to a decrease in the liver function. King and Stewart,3 in the course of an investigation of the cause of References 1. Morawitz and Bierich: Arch f. exper. Path. u. Pharmakol. , 1907, lvi, 115. 2. Kunika, S.: Deutsch. Ztschr. f. Chir. , 1912, cxviii, 574.Crossref 3. King and Stewart: Jour. Exper. Med. , 1909, xi, 673.Crossref 4. King, Bigelow and Pearce: Jour. Exper. Med. , 1911, xiv, 159. 5. Lee, Roger I., and Vincent, Beth: The Coagulation of Normal Human Blood , The Archives Int. Med. , 1914, xiii, 398.Crossref 6. Lee and White: Am. Jour. Med. Sc. , 1913, cxlv, 495.Crossref

Journal

Archives of Internal Medicine – American Medical Association

Published: Jul 1, 1915

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