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Yau EHS Hayes LA (1992)
Symmetrical peripheral gangrene: association with noradrenaline administrationIntensive Care Med., 18
Kaj Johansen, Terence Murphy, E. Pavlin, Daniel Ledbetter (1991)
Digital ischemia complicating pneumococcal sepsis: reversal with sympathetic blockade.Critical care medicine, 19 1
J. Holzer, J. Karliner, R. O'rourke, W. Pitt, J. Ross (1973)
Effectiveness of dopamine in patients with cardiogenic shock.The American journal of cardiology, 32 1
V. Falanga, L. Schachner, V. Rae, P. Ceballos, A. González, G. Liang, Ray Banks (1994)
Dermatologic consultations in the hospital setting.Archives of dermatology, 130 8
M. Winkler, D. Trunkey (1981)
Dopamine gangrene. Association with disseminated intravascular coagulation.American journal of surgery, 142 5
Abstract Symmetric peripheral gangrene (SPG) presents acutely as symmetric acral necrosis without large vessel obstruction or vasculitis.1 While relatively rare, this syndrome has been well described in the critical care literature, mainly in the context of septic shock, disseminated intravascular coagulation (DIC), and as an uncommon presentation of purpura fulminans. Vasopressors have been implicated directly or as a contributory cause in many cases.1 Dermatologists often receive referrals from the intensive care unit, frequently for the evaluation of purpura or necrosis in the setting of septic shock and DIC.2 We present 2 cases of dopamine hydrochloride— associated SPG seen over the course of 9 months. Report of Cases. Case 1. A 65-year-old white man with recurrent metastatic transitional cell carcinoma of the bladder presented with vomiting, diarrhea, and a 7.6-kg weight loss. He had received chemotherapy consisting of cisplatin, sodium methotrexate, and vincristine sulfate prior to admission. References 1. Johansen K, Murphy T, Pavlin E, et al. Digital ischemia complicating pneumococcal sepsis: reversal with sympathetic blockade . Crit Care Med. 1991; 19:114-116.Crossref 2. Falanga V, Schachner LA, Rae V, et al. Dermatologic consultations in the hospital setting . Arch Dermatol. 1994;130:1022-1025.Crossref 3. Holzer J, Karliner JS, O'Rourke RA, Pitt W, Ross J Jr. Effectiveness of dopamine in patients with cardiogenic shock . Am J Cardiol. 1973;32:79-84.Crossref 4. Winkler MJ, Trunkey DD. Dopamine gangrene association with disseminated intravascular coagulation . Am J Surg. 1981;142:588-591.Crossref 5. Hayes LA, Yau EHS, Hinds CJ, Watson JD. Symmetrical peripheral gangrene: association with noradrenaline administration . Intensive Care Med. 1992;18: 433-436.Crossref
Archives of Dermatology – American Medical Association
Published: Feb 1, 1997
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