Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Papular Mucinosis and Human Immunodeficiency Virus Infection

Papular Mucinosis and Human Immunodeficiency Virus Infection Abstract To the Editor.— Most cutaneous disorders associated with the human immunodeficiency virus (HIV) infection are of infectious or neoplastic origin. Dermal connective-tissue processes have received only passing mention.1,2 We describe two patients with symptomatic HIV-infection and papular mucinosis (lichen myxedematosus). Report of Cases.—Case 1.— A 35-year-old homosexual man with symptomatic HIV infection had been found to be HIV seropositive in February 1984. In October 1990, he gave an 8-month history of an asymptomatic generalized papular eruption on his trunk and thighs. The patient denied L-tryptophan ingestion.Findings from his physical examination revealed multiple 2- to 4-mm flesh-colored papules concentrated on his trunk and thighs. They were firm and smooth on their surface (Fig 1). There was no induration or thickening of the affected skin. Ten months later, the lesions were essentially unchanged. None of the papules had resolved, and there were no newly affected areas. The lesions showed no tendency to become confluent, and sclerodermoid changes were absent. References 1. Ghadially R, Sibbald RG, Walter JB, Haberman HF. Granuloma annulare in patients with human immunodeficiency virus infection . J Am Acad Dermatol. 1989;20:232-235.Crossref 2. Huerter CJ, Bass J, Bergfeld WF, Tubbs RR. Perforating granuloma annulare in a patient with acquired immunodeficiency syndrome: immunohistologic evaluation of the cellular infiltrate . Arch Dermatol . 1987;123:1217-1220.Crossref 3. Berger TG, Sawchuck WS, Leonardi C, Langenberg A, Tappero J, LeBoit PE. Epidermodysplasia verruciformis-associated papillomavirus infection complicating human immunodeficiency virus disease . Br J Dermatol. 1991;124;79-83.Crossref 4. Truhan AP, Roenigk HH. The cutaneous mucinosis . J Am Acad Dermatol. 1986;14:1-18.Crossref 5. Montgomery H, Underwood LJ. Lichen myxedematosus (differentiation from cutaneous mixedemas or mucoid states) . J Invest Dermatol. 1953:20;213-233. 6. Dubin DB, Kwan TH, Morse MO, Case DC. Cutaneous mucinosis in a patient with eosinophilia-myalgia syndrome associated with L-tryptophan ingestion . Arch Dermatol. 1990:126;1517-1518.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Papular Mucinosis and Human Immunodeficiency Virus Infection

Download PDF
2 pages

Loading next page...
 
/lp/american-medical-association/papular-mucinosis-and-human-immunodeficiency-virus-infection-MRhVd0DX1O

References (6)

Publisher
American Medical Association
Copyright
Copyright © 1992 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1992.01680170131028
Publisher site
See Article on Publisher Site

Abstract

Abstract To the Editor.— Most cutaneous disorders associated with the human immunodeficiency virus (HIV) infection are of infectious or neoplastic origin. Dermal connective-tissue processes have received only passing mention.1,2 We describe two patients with symptomatic HIV-infection and papular mucinosis (lichen myxedematosus). Report of Cases.—Case 1.— A 35-year-old homosexual man with symptomatic HIV infection had been found to be HIV seropositive in February 1984. In October 1990, he gave an 8-month history of an asymptomatic generalized papular eruption on his trunk and thighs. The patient denied L-tryptophan ingestion.Findings from his physical examination revealed multiple 2- to 4-mm flesh-colored papules concentrated on his trunk and thighs. They were firm and smooth on their surface (Fig 1). There was no induration or thickening of the affected skin. Ten months later, the lesions were essentially unchanged. None of the papules had resolved, and there were no newly affected areas. The lesions showed no tendency to become confluent, and sclerodermoid changes were absent. References 1. Ghadially R, Sibbald RG, Walter JB, Haberman HF. Granuloma annulare in patients with human immunodeficiency virus infection . J Am Acad Dermatol. 1989;20:232-235.Crossref 2. Huerter CJ, Bass J, Bergfeld WF, Tubbs RR. Perforating granuloma annulare in a patient with acquired immunodeficiency syndrome: immunohistologic evaluation of the cellular infiltrate . Arch Dermatol . 1987;123:1217-1220.Crossref 3. Berger TG, Sawchuck WS, Leonardi C, Langenberg A, Tappero J, LeBoit PE. Epidermodysplasia verruciformis-associated papillomavirus infection complicating human immunodeficiency virus disease . Br J Dermatol. 1991;124;79-83.Crossref 4. Truhan AP, Roenigk HH. The cutaneous mucinosis . J Am Acad Dermatol. 1986;14:1-18.Crossref 5. Montgomery H, Underwood LJ. Lichen myxedematosus (differentiation from cutaneous mixedemas or mucoid states) . J Invest Dermatol. 1953:20;213-233. 6. Dubin DB, Kwan TH, Morse MO, Case DC. Cutaneous mucinosis in a patient with eosinophilia-myalgia syndrome associated with L-tryptophan ingestion . Arch Dermatol. 1990:126;1517-1518.Crossref

Journal

Archives of Dermatology – American Medical Association

Published: Jul 1, 1992

There are no references for this article.