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Hypopigmented, Hyperkeratotic Papules in Two Siblings

Hypopigmented, Hyperkeratotic Papules in Two Siblings Abstract REPORT OF CASES An 18-year-old black woman presented with asymptomatic disseminated hypopigmented and hyperpigmented papules on her trunk and extremities. She had a history of asymptomatic keratoses since childhood as well as a history of cystic acne and hidradenitis suppurativa. Her family history was significant for a brother and mother with similar hypopigmented and hyperpigmented lesions in the same distribution. On physical examination, she had numerous 1- to 3-mm hypopigmented, hyperkeratotic, flat-topped, nonfollicular papules involving the extremities and trunk with extension to the neck and ears. The hypopigmented papules appeared to be unrelated to any previous lesions. She also had hyperpigmented papules on the distal extremities and the dorsa of her hands and feet (Fig 1). Skin markings were preserved in these lesions. Hyperpigmented macules with central pitting were also observed on her palms and soles. No oral lesions were present. A biopsy specimen was taken from one of the References 1. Morrow P. Keratosis follicularis . J Cutan Venereol Dis. 1886;4:257-264. 2. Darier J. De la porospermose folliculaire vegetante . Ann Dermatol Syphiligr. 1889;10:597. 3. White JC. A case of keratosis (ichthyosis) follicularis . J Cutan Genitourin Dis. 1889;7:201-209. 4. Getzler NA, Flint A. Keratosis follicularis . Arch Dermatol. 1966;93:545-549.Crossref 5. Goodall JWD, Richmond QMS. A case of Darier's disease . Br J Clin Pract. 1965;19:475-476. 6. Cattano AN. An unusual case of keratosis follicularis . Arch Dermatol. 1968;98:168-174.Crossref 7. Cornelison RL, Smith EB, Knox JM. Guttate leukoderma in Darier's disease . Arch Dermatol. 1970;102:447-450.Crossref 8. Berth-Jones J, Hutchinson PE. Darier's disease with peri-follicular depigmentation . Br J Dermatol. 1989;120:827-830.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Hypopigmented, Hyperkeratotic Papules in Two Siblings

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References (10)

Publisher
American Medical Association
Copyright
Copyright © 1992 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1992.01680130113017
Publisher site
See Article on Publisher Site

Abstract

Abstract REPORT OF CASES An 18-year-old black woman presented with asymptomatic disseminated hypopigmented and hyperpigmented papules on her trunk and extremities. She had a history of asymptomatic keratoses since childhood as well as a history of cystic acne and hidradenitis suppurativa. Her family history was significant for a brother and mother with similar hypopigmented and hyperpigmented lesions in the same distribution. On physical examination, she had numerous 1- to 3-mm hypopigmented, hyperkeratotic, flat-topped, nonfollicular papules involving the extremities and trunk with extension to the neck and ears. The hypopigmented papules appeared to be unrelated to any previous lesions. She also had hyperpigmented papules on the distal extremities and the dorsa of her hands and feet (Fig 1). Skin markings were preserved in these lesions. Hyperpigmented macules with central pitting were also observed on her palms and soles. No oral lesions were present. A biopsy specimen was taken from one of the References 1. Morrow P. Keratosis follicularis . J Cutan Venereol Dis. 1886;4:257-264. 2. Darier J. De la porospermose folliculaire vegetante . Ann Dermatol Syphiligr. 1889;10:597. 3. White JC. A case of keratosis (ichthyosis) follicularis . J Cutan Genitourin Dis. 1889;7:201-209. 4. Getzler NA, Flint A. Keratosis follicularis . Arch Dermatol. 1966;93:545-549.Crossref 5. Goodall JWD, Richmond QMS. A case of Darier's disease . Br J Clin Pract. 1965;19:475-476. 6. Cattano AN. An unusual case of keratosis follicularis . Arch Dermatol. 1968;98:168-174.Crossref 7. Cornelison RL, Smith EB, Knox JM. Guttate leukoderma in Darier's disease . Arch Dermatol. 1970;102:447-450.Crossref 8. Berth-Jones J, Hutchinson PE. Darier's disease with peri-follicular depigmentation . Br J Dermatol. 1989;120:827-830.Crossref

Journal

Archives of Dermatology – American Medical Association

Published: Mar 1, 1992

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