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M. Mathews-Roth, M. Pathak, T. Fitzpatrick, L. Harber, E. Kass (1974)
Beta-carotene as an oral photoprotective agent in erythropoietic protoporphyria.JAMA, 228 8
M. Mathews-Roth, M. Pathak, T. Fitzpatrick, L. Harber, E. Kass (1970)
Beta-carotene as a photoprotective agent in erythropoietic protoporphyria.Transactions of the Association of American Physicians, 83
I. Magnus, I. Magnus, A. Jarrett, T. Prankerd, C. Rimington (1961)
Erythropoietic protoporphyria. A new porphyria syndrome with solar urticaria due to protoporphyrinaemia.Lancet, 2 7200
Poh-Fitzpatrick MB DeLeo VA (1976)
Erythropoietic protoporphyriaAm J Med, 60
Cripps Dj, Scheuer Pj (1965)
Hepatobiliary changes in erythropoietic protoporphyria.Archives of pathology, 80
V. Deleo, M. Poh-Fitzpatrick, M. Mathews-Roth, L. Harber (1976)
Erythropoietic protoporphyria. 10 years experience.The American journal of medicine, 60 1
Abstract REPORT OF A CASE A 6-year-old boy presented with a three-year history of burning sensation and pruritus. The areas of involvement included the face, neck, and arms; symptoms worsened after periods of sun exposure. There was no history of rash, urticaria, petechiae, or edema. The patient was taking no medications, and his medical history and family history were unremarkable.Cutaneous examination revealed multiple 1- to 2-mm depressed scars on both cheeks (Fig 1). No erythema, blisters, or other abnormalities were noted. QUESTIONS For each of the following multiple-choice questions, choose the best answer(s) (answers follow discussion). What is your diagnosis? Hydroa vacciniforme Lupus erythematosus Polymorphous light eruption Ulerythema ophryogenes Erythropoietic protoporphyria Hutchinson's summer prurigo A biopsy specimen was obtained from the patient's forearm (Fig 2). Based on the clinical and histologic findings, which would be the most appropriate laboratory test(s) to References 1. DeLeo VA, Poh-Fitzpatrick MB, Mathews-Roth MM, et al: Erythropoietic protoporphyria . Am J Med 1976;60:8-22.Crossref 2. Magnus IA, Jarrett A, Prankerd TAJ, et al: Erythropoietic protoporphyria: A new porphyria syndrome with solar urticaria due to protoporphyrinaemia . Lancet 1961;2:448-451.Crossref 3. Cripps DJ, Scheuer PJ: Hepatobiliary changes in erythropoietic protoporphyria . Arch Pathol Lab Med 1965;80:500-508. 4. Mathews-Roth MM, Pathak MA, Fitzpatrick TB, et al: Betacarotene as a photoprotective agent in erythropoietic protoporphyria . N Engl J Med 1970;282:1231-1234.Crossref 5. Mathews-Roth MM, Pathak MA, Fitzpatrick TB, et al: Betacarotene as an oral photoprotective agent in erythropoietic protoporphyria . JAMA 1974;228:1004-1008.Crossref
Archives of Dermatology – American Medical Association
Published: Jul 1, 1985
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