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Vesiculopustular Eruption of Ulcerative Colitis

Vesiculopustular Eruption of Ulcerative Colitis Abstract To the Editor.— We read the excellent case report by Fenske et al1 in the August Archives of a patient with ulcerative colitis who had an evanescent, vesiculopustular eruption with a clinical course paralleling that of his gastrointestinal tract disease. We2 recently described four patients with bowel-bypass syndrome without bowel bypass and on further evaluation have categorized these cases as pustular vasculitis of bowel disease.3 The combination of pustular cutaneous lesions on purpuric bases in a truncal distribution with serum sickness-like symptoms and cutaneous histopathologic findings of "Sweet's-like" dermal changes in patients with bowel disease define the syndrome.Fenske and his group have carefully considered a wide differential diagnosis in their patient. The clinical photographs were reminiscent of our patients (two of whom had inflammatory bowel disease). The published dermatopathology photographs of Fenske et al primarily show the epidermis, however, a "perivascular mixed infiltrate of neutrophils, histiocytes, References 1. Fenske NA, Gern JE, Pierce D, et al: Vesiculopustular eruption of ulcerative colitis . Arch Dermatol 1983;119:664-669.Crossref 2. Jorizzo JL, Apisarnthanarax P, Subrt P, et al: Bowel-bypass syndrome without bowel bypass: Bowel-associated dermatosis-arthritis syndrome . Arch Intern Med 1983;143:457-461.Crossref 3. Jorizzo JL, Pustular vasculitis: An emerging disease concept . J Am Acad Dermatol 1983;9:160-162.Crossref 4. Ely PH: The bowel bypass syndrome: A response to bacterial peptidoglycans . J Am Acad Dermatol 1980;2:473-487.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Vesiculopustular Eruption of Ulcerative Colitis

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Vesiculopustular Eruption of Ulcerative Colitis

Abstract

Abstract To the Editor.— We read the excellent case report by Fenske et al1 in the August Archives of a patient with ulcerative colitis who had an evanescent, vesiculopustular eruption with a clinical course paralleling that of his gastrointestinal tract disease. We2 recently described four patients with bowel-bypass syndrome without bowel bypass and on further evaluation have categorized these cases as pustular vasculitis of bowel disease.3 The combination of pustular cutaneous lesions...
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References (4)

Publisher
American Medical Association
Copyright
Copyright © 1984 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1984.01650450022009
Publisher site
See Article on Publisher Site

Abstract

Abstract To the Editor.— We read the excellent case report by Fenske et al1 in the August Archives of a patient with ulcerative colitis who had an evanescent, vesiculopustular eruption with a clinical course paralleling that of his gastrointestinal tract disease. We2 recently described four patients with bowel-bypass syndrome without bowel bypass and on further evaluation have categorized these cases as pustular vasculitis of bowel disease.3 The combination of pustular cutaneous lesions on purpuric bases in a truncal distribution with serum sickness-like symptoms and cutaneous histopathologic findings of "Sweet's-like" dermal changes in patients with bowel disease define the syndrome.Fenske and his group have carefully considered a wide differential diagnosis in their patient. The clinical photographs were reminiscent of our patients (two of whom had inflammatory bowel disease). The published dermatopathology photographs of Fenske et al primarily show the epidermis, however, a "perivascular mixed infiltrate of neutrophils, histiocytes, References 1. Fenske NA, Gern JE, Pierce D, et al: Vesiculopustular eruption of ulcerative colitis . Arch Dermatol 1983;119:664-669.Crossref 2. Jorizzo JL, Apisarnthanarax P, Subrt P, et al: Bowel-bypass syndrome without bowel bypass: Bowel-associated dermatosis-arthritis syndrome . Arch Intern Med 1983;143:457-461.Crossref 3. Jorizzo JL, Pustular vasculitis: An emerging disease concept . J Am Acad Dermatol 1983;9:160-162.Crossref 4. Ely PH: The bowel bypass syndrome: A response to bacterial peptidoglycans . J Am Acad Dermatol 1980;2:473-487.Crossref

Journal

Archives of Dermatology – American Medical Association

Published: Sep 1, 1984

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