Access the full text.
Sign up today, get DeepDyve free for 14 days.
Helwig EB Brownstein MH (1970)
The cutaneous amyloidoses: II. Systemic formsArch Dermatol, 102
Block WD Rukavina JG (1956)
Primary systemic amyloidosis: A review and an experimental, genetic, and clinical study of 29 cases with particular emphasis on the familial formMedicine, 35
Cohen AS Rubinow A (1978)
Skin involvement in generalized amyloidosis: A study of clinically involved and uninvolved skin in 50 patients with primary or secondary amyloidosisAnn Intern Med, 88
Black MM Breathnach SM (1979)
Systemic amyloidosis and the skin: A review with special emphasis on clinical features and therapyClin Exp Dermatol, 4
Goltz RW (1952)
Systematized amyloidosis: A review of skin and mucous membrane lesions and a report of two casesMedicine, 31
Abstract Cutaneous involvement is a frequent clinical and pathologic finding in amyloidosis associated with plasma cell dyscrasias.1,2 Common clinical features include purpura, papules, nodules, plaques, and scleroderma-like changes.2-5 We describe herein a patient in whom generalized hair loss and anonychia were early prominent manifestations of unsuspected amyloidosis and multiple myeloma. Report of a Case A 65-year-old woman was referred to us for examination and treatment of congestive heart failure in October 1980. Orthopnea, paroxysmal nocturnal dyspnea, and pedal edema had initially developed in 1977 and had responded to therapy with digoxin and hydrochlorothiazide until one month earlier. Coincidentally with the onset of heart disease, the patient had noticed brittleness of her fingernails and the gradual loss of all body hair. She had worn a wig for the past 18 months. Her only other symptoms included a 5.5-kg weight loss and dysarthria of three months' duration.Physical examination at the References 1. Rubinow A, Cohen AS: Skin involvement in generalized amyloidosis: A study of clinically involved and uninvolved skin in 50 patients with primary or secondary amyloidosis . Ann Intern Med 1978;88:781-785.Crossref 2. Brownstein MH, Helwig EB: The cutaneous amyloidoses: II. Systemic forms . Arch Dermatol 1970;102:20-28.Crossref 3. Goltz RW: Systematized amyloidosis: A review of skin and mucous membrane lesions and a report of two cases . Medicine 1952;31:381-409.Crossref 4. Rukavina JG, Block WD, Jackson CE, et al: Primary systemic amyloidosis: A review and an experimental, genetic, and clinical study of 29 cases with particular emphasis on the familial form . Medicine 1956;35:239-334.Crossref 5. Breathnach SM, Black MM: Systemic amyloidosis and the skin: A review with special emphasis on clinical features and therapy . Clin Exp Dermatol 1979;4:517-536.Crossref
Archives of Dermatology – American Medical Association
Published: Dec 1, 1981
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.