Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Keratoacanthomas Arising in Hypertrophic Lichen Planus: A Case Report

Keratoacanthomas Arising in Hypertrophic Lichen Planus: A Case Report Abstract Keratoacanthoma is a keratinizing, squamous neoplasm characterized by rapid growth and spontaneous involution occurring most commonly on the sun-exposed skin of elderly white persons.1-4 Postulated causes of this tumor include ultraviolet energy, ionizing radiation, chemical carcinogens, trauma, viral infection, and genetic and immunologic factors.1,2 Lichen planus is an inflammatory papulosquamous disorder of unknown cause in which immunologic abnormalities, drugs, or viral infection have been thought to play a role.4 We recently treated a patient who had keratoacanthomas arising in lesions of hypertrophic lichen planus. To our knowledge, the concordant occurrence of these two disorders has not been previously reported. Report of a Case A 69-year-old woman was referred to our dermatology service for evaluation of three nodular growths of four weeks' duration on her right pretibial area. She also had had a pruritic eruption on the lower part of her legs for one year, with minimal response References 1. Schwartz RA: The keratoacanthoma: A review . J Surg Oncol 1979; 12:305-317.Crossref 2. Botero F: Keratoacanthoma: Clinical and therapeutic considerations . Primary Care 1978;5:313-323. 3. Rapaport J: Giant keratoacanthoma of the nose . Arch Dermatol 1975;111:73-75.Crossref 4. Arndt KA: Disorders of the dermis and dermoepidermal interface , in Fitzpatrick TB, Eisen AZ, Wolff K, et al (eds): Dermatology in General Medicine , ed 2. New York, McGraw-Hill Book Co, 1979, pp 655-661. 5. Lyell A, Whittle CH: Lichen planus with squamous carcinoma . Br J Dermatol 1951;63:69. 6. Wilson H: Hypertrophic lichen planus with epitheliomata . Br J Dermatol 1953;65:379-380. 7. Andreason JO, Pinborg JJ: Cancer Udvikling: Oral lichen planus . Nord Med 1963;70:861-866. 8. Kronenberg K, Fretzin D, Potter B: Malignant degeneration of lichen planus . Arch Dermatol 1971;104:304-307.Crossref 9. Fulling H-J: Cancer development in oral lichen planus: A follow-up study of 327 patients . Arch Dermatol 1973;108:667-669.Crossref 10. Warin RP: Epithelioma following lichen planus of the mouth . Br J Dermatol 1960;72:288-291.Crossref 11. Wasik F, Woyton A, Birecka I: Oral florid papillomatosis in the course of lichen planus . Br J Dermatol 1974;90:381-386.Crossref 12. Reisman RJ, Schwartz AE, Friedman EW, et al: The malignant potential of oral lichen planus: Diagnostic pitfalls . Oral Surg 1974;38:227-232.Crossref 13. Thomson S: Molluscum sebaceum and its surgical significance . Ann R Coll Surg Engl 1958;22:382-400. 14. Baer RL, Kopf AW: Year Book of Dermatology . Chicago, Year Book Medical Publishers, 1963, pp 7-41. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Keratoacanthomas Arising in Hypertrophic Lichen Planus: A Case Report

Archives of Dermatology , Volume 117 (8) – Aug 1, 1981

Loading next page...
 
/lp/american-medical-association/keratoacanthomas-arising-in-hypertrophic-lichen-planus-a-case-report-tRYQ6jTiH0

References (15)

Publisher
American Medical Association
Copyright
Copyright © 1981 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1981.01650080073035
Publisher site
See Article on Publisher Site

Abstract

Abstract Keratoacanthoma is a keratinizing, squamous neoplasm characterized by rapid growth and spontaneous involution occurring most commonly on the sun-exposed skin of elderly white persons.1-4 Postulated causes of this tumor include ultraviolet energy, ionizing radiation, chemical carcinogens, trauma, viral infection, and genetic and immunologic factors.1,2 Lichen planus is an inflammatory papulosquamous disorder of unknown cause in which immunologic abnormalities, drugs, or viral infection have been thought to play a role.4 We recently treated a patient who had keratoacanthomas arising in lesions of hypertrophic lichen planus. To our knowledge, the concordant occurrence of these two disorders has not been previously reported. Report of a Case A 69-year-old woman was referred to our dermatology service for evaluation of three nodular growths of four weeks' duration on her right pretibial area. She also had had a pruritic eruption on the lower part of her legs for one year, with minimal response References 1. Schwartz RA: The keratoacanthoma: A review . J Surg Oncol 1979; 12:305-317.Crossref 2. Botero F: Keratoacanthoma: Clinical and therapeutic considerations . Primary Care 1978;5:313-323. 3. Rapaport J: Giant keratoacanthoma of the nose . Arch Dermatol 1975;111:73-75.Crossref 4. Arndt KA: Disorders of the dermis and dermoepidermal interface , in Fitzpatrick TB, Eisen AZ, Wolff K, et al (eds): Dermatology in General Medicine , ed 2. New York, McGraw-Hill Book Co, 1979, pp 655-661. 5. Lyell A, Whittle CH: Lichen planus with squamous carcinoma . Br J Dermatol 1951;63:69. 6. Wilson H: Hypertrophic lichen planus with epitheliomata . Br J Dermatol 1953;65:379-380. 7. Andreason JO, Pinborg JJ: Cancer Udvikling: Oral lichen planus . Nord Med 1963;70:861-866. 8. Kronenberg K, Fretzin D, Potter B: Malignant degeneration of lichen planus . Arch Dermatol 1971;104:304-307.Crossref 9. Fulling H-J: Cancer development in oral lichen planus: A follow-up study of 327 patients . Arch Dermatol 1973;108:667-669.Crossref 10. Warin RP: Epithelioma following lichen planus of the mouth . Br J Dermatol 1960;72:288-291.Crossref 11. Wasik F, Woyton A, Birecka I: Oral florid papillomatosis in the course of lichen planus . Br J Dermatol 1974;90:381-386.Crossref 12. Reisman RJ, Schwartz AE, Friedman EW, et al: The malignant potential of oral lichen planus: Diagnostic pitfalls . Oral Surg 1974;38:227-232.Crossref 13. Thomson S: Molluscum sebaceum and its surgical significance . Ann R Coll Surg Engl 1958;22:382-400. 14. Baer RL, Kopf AW: Year Book of Dermatology . Chicago, Year Book Medical Publishers, 1963, pp 7-41.

Journal

Archives of DermatologyAmerican Medical Association

Published: Aug 1, 1981

There are no references for this article.